33 products were found matching "K08959"!

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human CSNK1d. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human CSNK1d....

Longdaysin is an inhibitor of casein kinase 1delta (CK1delta) and CK1alpha (IC50 = 12 µM for both). It also inhibits cyclin-dependent kinase 2 (Cdk2), Cdk7, MAPK, and MAP3K (IC50s = 13, 32, 59, and 92 µM, respectively). Longdaysin increases the circadian period of U2OS cells by one and five hours when used at...

CK1-IN-1 is an inhibitor of casein kinase 1delta (CK1delta) and CK1epsilon (IC50s = 15 and 16 nM, respectively). It is selective for CK1delta and CK1epsilon over TGF-beta receptor type 1 (ALK5, IC50 = 151.8 nM) and TGF-beta receptor type 2 (TGFBR2) at 1 µM.Formal Name:...

Protein function: Essential serine/threonine-protein kinase that regulates diverse cellular growth and survival processes including Wnt signaling, DNA repair and circadian rhythms. It can phosphorylate a large number of proteins. Casein kinases are operationally defined by their preferential utilization of acidic...

SR 3029 is an inhibitor of casein kinase 1delta (CK1delta) and CK1epsilon (IC50s = 44 and 260 nM, respectively). It is selective for CK1delta and CK1epsilon over 438 kinases in a panel but also inhibits MYLK4, FLT3, Cdk4/cyclin D1, and MARK2 by greater than 90% at 10 µM. SR 3029 inhibits Cdk4/cyclin D1, Cdk4/cyclin...

The casein kinase 1 (CK1) family of kinases regulate diverse processes, particularly related to circadian rhythms and sensitivity to amphetamines. PF-670462 is a potent inhibitor of the CK1 isoforms CK1epsilon and CK1delta (IC50 = 7.7 and 14 nM, respectively). It less effectively inhibits a wide variety of related...

Epiblastin A is an ATP-competitive inhibitor of the casein kinase 1 (CK1) isoforms alpha, delta, and epsilon (IC50s = 8.9, 0.5, and 4.7 µM, respectively). It is selective for CK1alpha, CK1delta, and CK1epsilon at concentrations below 10 µM, however, it also inhibits BRSK1, EEF2K, EGFR, MNK-2, and RIPK2 (IC50s =...

TA-01 is a derivative of the p38 MAPK inhibitor SB 203580 (Cay-13067, Cay-13344) and an inducer of cardiomyocyte differentiation. It is cardiomyogenic at concentrations less than 5 µM, increasing expression of the cardiomyocyte marker NKX2-5 by 2.2-fold and decreasing expression of mesoderm markers and the...

Protein function: Essential serine/threonine-protein kinase that regulates diverse cellular growth and survival processes including Wnt signaling, DNA repair and circadian rhythms. It can phosphorylate a large number of proteins. Casein kinases are operationally defined by their preferential utilization of acidic...

Full length Recombinant CK1δ also known as CSNK1D, HCKID, and CK1D. Genbank Accession NM_001893 with N-terminal GST-tag, expressed in Sf9 cells via a baculovirus expression system. MW = 72kDa.

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Casein kinase 1, delta Protein function: Essential serine/threonine-protein kinase that regulates diverse cellular growth and survival processes including Wnt signaling, DNA repair and circadian...

LH 846 is a benzothiazole analog that selectively inhibits casein kinase (CK) 1delta (IC50 = 290 nM). It inhibits CK1epsilon and CK1alpha at much higher concentrations (IC50s = 1.3 and 2.5 µM, respectively) but does not inhibit CK2. LH 846 has been shown to inhibit CK1delta-dependent phosphorylation and degradation...