68 products were found matching "K08957"!

Description: CK1 alpha/CSNK1A1 Protein, Human, Recombinant (His) is expressed in E. coli. The accession number is P48729.

TMX-4116 is a casein kinase 1alpha (CK1alpha) degrader. It selectively induces E3 ubiquitin ligase-mediated degradation of CK1alpha over phosphodiesterase 6D (PDE6D), Ikaros family zinc finger protein 1 (IKZF1), and IKZF3 in MM.1S cells when used at concentrations ranging from 0.04 to 1 µM. SMILES...

Rabbit Polyclonal CSNK1A1 Antibody against Human casein kinase 1 alpha 1. Validated for Western Blot. Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Interspecies information: Highest antigen sequence indentity to the following orthologs: ENSMUSG00000024576: 100%,...

Protein function: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in...

CKI-7 is an inhibitor of casein kinase 1 (CK1, Ki = 8.5 µM). It is selective for CK1 over CK2, PKC, CaM kinase II (CaMKII), and cyclic AMP-dependent protein kinase (IC50s = 90, >1,000, 195, and 550 µM, respectively). CKI-7 inhibits phosphorylation of a peptide substrate by Leishmania CK1.2 by 50% when used at a...

Description: Casein kinase I isoform alpha, also known as CKI-alpha, CK1 and CSNK1A1, is a cytoplasm protein which belongs to theprotein kinase superfamily, CK1 Ser/Thr protein kinase family and casein kinase I subfamily. Casein kinases are operationally defined by their preferential utilization of acidic proteins...

Protein function: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in...

Protein function: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in...

Full length recombinant human CK1 alpha 1 also known as CSNK1A1, CK1, HLCDGP1, PRO2975, CK1A1. Genbank Accession NM_001892 with an N-terminal GST-tag, expressed in Sf9 cells via a baculovirus expression system. MW = 62kDa.

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Casein kinase I isoform alpha is an enzyme that in humans is encoded by the CSNK1A1 gene. The CSNK1A1 gene is mapped to chromosome 5q32 based on an alignment of the CSNK1A1 sequence with the genomic sequence (GRCh37). It is reported that both screens identified...

Epiblastin A is an ATP-competitive inhibitor of the casein kinase 1 (CK1) isoforms alpha, delta, and epsilon (IC50s = 8.9, 0.5, and 4.7 µM, respectively). It is selective for CK1alpha, CK1delta, and CK1epsilon at concentrations below 10 µM, however, it also inhibits BRSK1, EEF2K, EGFR, MNK-2, and RIPK2 (IC50s =...

Human Casein Kinase 1alpha1, also known as CSNK1A1 (GenBank Accession NM_001892, (no tag). a.a 2-337 (end). Expressed in an insect Sf9 cell expression system. MW=65 kDa.