86 products were found matching "K08857"!

Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. The NEK5 antibody targets Serine/threonine-protein kinase Nek5, an enzyme encoded by the NEK5 gene and belonging to the NIMA-related kinase (NEK) family. These kinases regulate cell cycle progression, centrosome dynamics, and DNA damage...

Protein function: Phosphorylates serines and threonines, but also appears to possess tyrosine kinase activity. Involved in DNA damage checkpoint control and for proper DNA damage repair. In response to injury that includes DNA damage, NEK1 phosphorylates VDAC1 to limit mitochondrial cell death (PubMed:20230784). May...

Protein function: Phosphorylates serines and threonines, but also appears to possess tyrosine kinase activity. Involved in DNA damage checkpoint control and for proper DNA damage repair. In response to injury that includes DNA damage, NEK1 phosphorylates VDAC1 to limit mitochondrial cell death (PubMed:20230784). May...

NEK4 (NIMA-related kinase 4) is a serine-threonine protein kinase related to the asperigillus NIMA (never-in-mitosis gene a) kinase. NEK4 is proposed to play a role in cell division. Alternative names for NEK4 include never in mitosis A-related kinase 4, NimA-related protein kinase 4, serine/threonine -protein...

NEK4 (NIMA-related kinase 4) is a serine-threonine protein kinase related to the asperigillus NIMA (never-in-mitosis gene a) kinase. NEK4 is proposed to play a role in cell division. Alternative names for NEK4 include never in mitosis A-related kinase 4, NimA-related protein kinase 4, serine/threonine -protein...

Nek5 (NimA-related protein kinase 5) is a 708 amino acid protein that is related to NIMA, a protein that was originally discovered in Aspergillus nidulans and is necessary for entry into mitosis. One of several members of the Set/Thr protein kinase super family, Nek5 contains one protein kinase domain through which...

Protein function: Protein kinase that seems to act exclusively upon threonine residues. Required for normal entry into proliferative arrest after a limited number of cell divisions, also called replicative senescence. Required for normal cell cycle arrest in response to double-stranded DNA damage. [The UniProt...

Protein function: Phosphorylates serines and threonines, but also appears to possess tyrosine kinase activity (PubMed:20230784). Involved in DNA damage checkpoint control and for proper DNA damage repair (PubMed:20230784). In response to injury that includes DNA damage, NEK1 phosphorylates VDAC1 to limit...

Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 57% and to rat: 59%

Protein function: Phosphorylates serines and threonines, but also appears to possess tyrosine kinase activity (PubMed:20230784). Involved in DNA damage checkpoint control and for proper DNA damage repair (PubMed:20230784). In response to injury that includes DNA damage, NEK1 phosphorylates VDAC1 to limit...

Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 49% and to rat: 49%

Protein function: Protein kinase that seems to act exclusively upon threonine residues. Required for normal entry into proliferative arrest after a limited number of cell divisions, also called replicative senescence. Required for normal cell cycle arrest in response to double-stranded DNA damage. [The UniProt...