- Search results for K08807
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21 products were found matching "K08807"!
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Item number: ELK-ELK6491.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PIM3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PIM3. Next,...
Keywords: | PIM3, EC=2.7.11.1, Serine/threonine-protein kinase pim-3 |
Application: | ELISA |
Species reactivity: | human |
From 365.00€
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Item number: Cay16245-5
The family of Pim (Provirus Integration site for Moloney murine leukemia virus) proteins are serine/threonine kinases involved in cell survival and cell proliferation. CX-6258 is a potent, reversible inhibitor of Pim-1, -2, and -3 (IC50s = 5, 25, and 16 nM, respectively). It demonstrates excellent selectivity,...
Keywords: | Pim-Kinase Inhibitor X,... |
Application: | Pim kinase inhibitor |
CAS | 1202916-90-2 |
MW: | 461.9 D |
From 66.00€
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Item number: BPS-41108
Recombinant human serine/threonine-protein kinase PIM3 (PIM3), GenBank Accession No. NM_145478, full-length with an N-terminal GST tag and expressed in a baculovirusinfected Sf9 insect cell expression system. MW = 63 kDa.
Keywords: | PIM3, EC=2.7.11.1, Serine/threonine-protein kinase pim-3, |
Application: | Studying enzyme kinetics, inhibitor screening, selectivity profiling |
Expressed in: | insect cells |
Origin: | human |
MW: | 63 kD |
862.00€
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Item number: G-HUFI01951.96
Application: | ELISA |
Species reactivity: | human |
641.00€
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Item number: SYN-1182-M010
Soluble in DMSO. CX6258 is a potent inhibitor of Pim-1, Pim-2 and Pim-3 with IC(50) values of 5, 25 and 16nM, respectively. Target: PKC - PKC alpha, , Kinase Group: STE , Substrate: Serine-Threonine
Keywords: | CX6258 |
Application: | Pim-1 / Pim-2 / Pim-3 inhibitor |
CAS | 1202916-90-2 |
MW: | 461,9 D |
From 250.00€
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Item number: Cay16423-5
The Pim family proteins are serine/threonine kinases involved in cancer progression. SGI-1776 is a potent inhibitor of all three human Pim kinases (IC50s = 7, 363, and 69 nM for Pim-1, Pim-2, and Pim-3, respectively). While it also inhibits FLT3 and haspin (IC50s = 44 and 34 nM, respectively), SGI-1776 has little...
Keywords: | Pim-Kinase Inhibitor IX, N-[(1-methyl-4-piperidinyl)methyl]-3-[3-(trifluoromethoxy)phenyl]-imidazo[1,2-b]pyridazin-6-amine |
Application: | Pim1 / Pim2 / Pim3 inhibitor |
CAS | 1025065-69-3 |
MW: | 405.4 D |
From 43.00€
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Item number: Cay20235-25
AZD 1208 is a potent, selective, and orally available inhibitor of all three forms of the proto-oncogene Pim kinase (IC50s = 0.4, 5.0, and 1.9 nM for Pim-1, Pim-2, and Pim-3, respectively). It causes cell cycle arrest and apoptosis in MOLM-16 megakaryoblastic leukemia cells and inhibits the growth of MOLM-16...
Keywords: | (5Z)-[[2-[(3R)-3-amino-1-piperidinyl][1,1'-biphenyl]-3-yl]methylene]-2,4-thiazolidinedione |
Application: | Pim-1 / Pim-2 / Pim-3 inhibitor |
CAS | 1204144-28-4 |
MW: | 379.5 D |
From 43.00€
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Item number: SYN-1214-M050
Potent, highly selective and orally available Pim kinase inhibitor that effectively inhibits all three isoforms Pim-1, Pim-2 and Pim-3 at < 5nM or < 150 nM in enzyme and cell assays, respectively. Potently inhibits colony growth and Pim signalling substrates in primary AML cells from bone marrow that are Flt3...
Keywords: | AZD-1208 |
Application: | Pim kinase inhibitor |
CAS | 1204144-28-4 |
MW: | 379,5 D |
From 79.00€
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Item number: SYN-1193-M010
Soluble in DMSO or ethanol. SGI-1776 is a novel ATP competitive inhibitor of Pim1 with an IC(50) of 7nM, 50- and 10-fold selectivity versus Pim2 and Pim3. Target: Pim1 - Pim2 - Pim3 , Kinase Group: CAMK , Substrate: Serine-Threonine
Keywords: | SGI1776 |
Application: | Pim1 / Pim2 / Pim3 inhibitor |
CAS | 1025065-69-3 |
MW: | 405,4 D |
From 106.00€
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Item number: ARG54877.100
Protein function: Proto-oncogene with serine/threonine kinase activity that can prevent apoptosis, promote cell survival and protein translation. May contribute to tumorigenesis through: the delivery of survival signaling through phosphorylation of BAD which induces release of the anti-apoptotic protein Bcl-X(L),...
Keywords: | Anti-PIM3, EC=2.7.11.1, Anti-Serine/threonine-protein kinase pim-3 |
Application: | IHC (paraffin), WB |
Host: | Rabbit |
Species reactivity: | human, mouse |
624.00€
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Item number: Cay29571-25
TP-3654 is an inhibitor of Pim kinases (Kis = 5, 239, and 42 nM for Pim-1, Pim-2, and Pim-3, respectively). It inhibits 19 additional kinases, including PI3Kalpha, PI3Kgamma, and PI3Kdelta, with IC50 values of less than 300 nM. TP-3654 inhibits phosphorylation of Bad in HEK293 cells overexpressing Bad and Pim-1...
Keywords: | trans-alpha,alpha-dimethyl-4-[[3-[3-(trifluoromethyl)phenyl]imidazo[1,2-b]pyridazin-6-yl]amino]-cyclohexanemethanol |
Application: | Pim kinase inhibitor |
CAS | 1361951-15-6 |
MW: | 418.5 D |
From 77.00€
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Item number: BPS-79886
The PIM3 Assay Kit is designed to measure PIM3 activity for screening and profiling applications using Kinase-Glo(R) MAX as a detection reagent.
Keywords: | Pim-3 proto-oncogene assay kit, serine/threonine kinase assay kit, |
Application: | Enzyme kinetics, drug discovery, HTS |
Species reactivity: | human |
789.00€
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