112 products were found matching "K08674"!

OncoFAP is a fibroblast activation protein (FAP) ligand. It binds to human FAP (Kd = 0. nM) and contains a carboxylic acid moiety that can be functionalized with various payloads for FAP-targeted delivery. OncoFAP has been conjugated to a variety of fluorophores and radioligands, which selectively accumulate in...

Protein function: Cell surface glycoprotein serine protease that participates in extracellular matrix degradation and involved in many cellular processes including tissue remodeling, fibrosis, wound healing, inflammation and tumor growth. Both plasma membrane and soluble forms exhibit post-proline cleaving...

The FAP Fluorescent Activity Assay kit is designed to measure FAP activity using purified FAP or FAP extracts. It comes in a convenient 96-well format, with purified FAP enzyme, FAP substrate, and FAP assay buffer for 100 enzyme reactions. The Key to FAP Fluorescent Activity Assay is the fluorogenic substrate. Using...

A fluorogenic substrate for FAP, AFC is released upon enzymatic cleavage by FAP and its fluorescence can be used to quantify FAP activity, ex/em = 400/505 nm, respectively

Active human FAP (GenBank Accession No. NM_004460), (amino acids 29-end) with C-terminal HIS tag, MW=85.5 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

Protein function: In association with DPP4 is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May have a role in tissue remodeling during development and wound healing, and contribute to invasiveness in malignant cancers. [The...

Z-Gly-Pro-pNA is a colorimetric substrate for prolyl endopeptidase. Enzymatic cleavage of Z-Gly-Pro-pNA releases p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nM as a measure of prolyl endopeptidase activity.Formal Name:...

Recombinant human FAP(30-760) protein with N-terminal 6×His tag. 6×His tag FAP(Arg30-Asp760), Protein function: Cell surface glycoprotein serine protease that participates in extracellular matrix degradation and involved in many cellular processes including tissue remodeling, fibrosis, wound healing, inflammation...

Natural and recombinant human Seprase. There is no detectable cross-reactivity with other relevant proteins. Protein function: Cell surface glycoprotein serine protease that participates in extracellular matrix degradation and involved in many cellular processes including tissue remodeling, fibrosis, wound healing,...

The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is...

The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is...

In 1X PBS, pH 7.4, with 0.09% sodium azide. Fibroblast activation protein is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and...