25 products were found matching "K08655"!

1G244 is an inhibitor of dipeptidyl peptidase 8 (DPP-8) and DPP-9 (IC50s = 14 and 53 nM, respectively). It is selective for DPP-8 and DPP-9 over DPP-4, DPP-2, and fibroblast activation protein (FAP, IC50s = >100 µM for all). 1G244 (20 µM) inhibits the differentiation of 3T3-L1 cells into adipocytes. It induces...

The DPP8 Fluorescent Activity Assay kit is designed to measure DPP8 activity using purified DPP8 or DPP8 extracts. It comes in a convenient 96-well format, with purified DPP8 enzyme, DPP8 substrate, and DPP8 assay buffer for 100 enzyme reactions. The Key to DPP8 Fluorescent Activity Assay is the fluorogenic...

Active human DPP8 (Dipeptidylpeptidase 8) (GenBank Accession No. NM_197960), (full length) with N-terminal GST tag, MW=129.3 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

Talabostat is a non-selective inhibitor of dipeptidyl peptidases (DPPs), including DPP-4, DPP-7, DPP-8, DPP-9, fibroblast activation protein (FAP), and prolyl endopeptidase (PREP, IC50s = >4, 310, 4, 11, 560, and 390 nM, respectively). It inhibits proliferation of superantigen-stimulated human peripheral blood...

Protein function: Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2. [The UniProt Consortium]

Protein function: Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 96% and to rat: 95%

Talabostat is an orally bioavailable non-selective inhibitor of dipeptidyl-peptidases (DPPs), including DPP-4, DPP-7/QPP, DPP-8, DPP-9, fibroblast activation protein (FAP) and prolyl endopeptidase (PREP, PEP) (IC50s = >4, 310, 4, 11, 560 and 390 nM, respectively). Talabostat induces powerful anti-tumor immune...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human DPP8. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human DPP8. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse DPP8. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse DPP8. Next,...

Description: Talabostat (PT100, Val-boroPro) is a potent, nonselective and orally available dipeptidyl peptidase IV (DPP-IV) inhibitor with a Ki of 0.18 nM. Target: Others. Smiles: CC(C)[C@H](N)C(=O)N1CCC[C@H]1B(O)O. References: Connolly BA, et al. Dipeptide boronic acid inhibitors of dipeptidyl peptidase IV:...

Description: Talabostat mesylate (PT100) is an orally active, selective inhibitor of dipeptidyl peptidases IV (DPP4, IC50: 0.18 nM), including tumor-associated fibroblast activation protein. This agent may also stimulate the production of colony stimulating factors, such as granulocyte colony-stimulating factor...

Protein function: Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2. [The UniProt Consortium]