31 products were found matching "K08653"!
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PF-429242 (hydrochloride)
Item number: Cay15140-1
PF-429242 is an inhibitor of site-1 protease with an IC50 value of 170 nM for human recombinant site-1 protease. It is selective for site-1 protease over trypsin, elastase, proteinase K, plasmin, kallikren, factor XIa, thrombin, and furin at concentrations up to 100 µM. PF-429242 completely inhibits proteolytic...
| Keywords: | 4-[(diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinyl-benzamide, dihydrochloride |
| Application: | MBTPS1 inhibitor, antiviral |
| CAS | 2248666-66-0 |
| MW: | 482.5 D |
From 78.00€
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Anti-MBTPS1
Item number: ARG56137.100
Protein function: Serine protease that catalyzes the first step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs). Other known substrates are BDNF, GNPTAB and ATF6. Cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4. Cleaves known substrates...
| Keywords: | Anti-SKI-1, Anti-MBTPS1, Anti-KIAA0091, EC=3.4.21.112, Anti-Endopeptidase S1P, Anti-Subtilisin/kexin-isozyme 1,... |
| Application: | WB, IHC (paraffin), ICC, IF |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
723.00€
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Anti-MBTPS1
Item number: ATA-HPA056109.100
Protein function: Serine protease that cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4: known substrates are SREBF1/SREBP1, SREBF2/SREBP2, BDNF, GNPTAB, ATF6 and ATF6B (PubMed:10644685, PubMed:12782636, PubMed:21719679). Cleaves substrates after Arg-Ser-Val-Leu (SREBP2),...
| Keywords: | Anti-SKI-1, Anti-Endopeptidase S1P, Anti-Subtilisin/kexin-isozyme 1, Anti-Membrane-bound transcription factor site-1 protease |
| Application: | IHC |
| Host: | Rabbit |
| Species reactivity: | human |
From 369.00€
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Membrane-bound transcription factor site-1 protease...
Item number: CSB-EP617930HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 218-414aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: DTGLSEKHPH FKNVKERTNW TNERTLDDGL GHGTFVAGVI ASMRECQGFA PDAELHIFRV FTNNQVSYTS WFLDAFNYAI LKKIDVLNLS IGGPDFMDHP FVDKVWELTA NNVIMVSAIG NDGPLYGTLN...
| Keywords: | SKI-1, Endopeptidase S1P, Subtilisin/kexin-isozyme 1, Membrane-bound transcription factor site-1 protease, Recombinant... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 37.5 kD |
From 292.00€
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Membrane-bound transcription factor site-1 protease...
Item number: CSB-EP617930HU1.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 187-400aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: RAIPRQVAQT LQADVLWQMG YTGANVRVAV FDTGLSEKHP HFKNVKERTN WTNERTLDDG LGHGTFVAGV IASMRECQGF APDAELHIFR VFTNNQVSYT SWFLDAFNYA ILKKIDVLNL SIGGPDFMDH PFVDKVWELT...
| Keywords: | SKI-1, Endopeptidase S1P, Subtilisin/kexin-isozyme 1, Membrane-bound transcription factor site-1 protease, Recombinant... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 27.8 kD |
From 292.00€
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Anti-MBTPS1 Monoclonal, clone 2F10E12
Item number: CSB-MA617930A0m.100
Host Species: Mouse. Isotype: IgG1. Buffer: Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: >95%, Protein G purified. Target Name: MBTPS1. Antigen Species: Human
| Keywords: | Anti-SKI-1, Anti-Endopeptidase S1P, Anti-Subtilisin/kexin-isozyme 1, Anti-Membrane-bound transcription factor site-1... |
| Application: | ELISA, WB, FC |
| Host: | Mouse |
| Species reactivity: | human |
From 206.00€
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Anti-MBTPS1
Item number: CSB-PA237035.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Keywords: | Anti-SKI-1, Anti-Endopeptidase S1P, Anti-Subtilisin/kexin-isozyme 1, Anti-Membrane-bound transcription factor site-1... |
| Application: | ELISA, WB |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
284.00€
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PF429242 dihydrochloride
Item number: TGM-T12437-100mg
Description: PF429242 dihydrochloride is a reversible and competitive inhibitor of S1P, with an IC50 of 175 nM. Target: S1P Receptor. Smiles: Cl.Cl.CCN(CC)Cc1ccc(cc1)C(=O)N(CCc1ccccc1OC)[C@@H]1CCNC1. References: Hawkins JL, et al. Pharmacologic inhibition of site 1 protease activity inhibits sterol regulatory...
| Application: | MBTPS1 inhibitor, antiviral |
| CAS | 2248666-66-0 |
| MW: | 482.49 D |
From 35.00€
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MBTPS1 Protein, Human, Recombinant (His & SUMO)
Item number: TGM-TMPH-01661-100ug
Description: MBTPS1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 37.5 kDa and the accession number is Q14703.
| Keywords: | MBTPS1, Endopeptidase S1P, Membrane-bound transcription factor site-1 protease, Subtilisin/kexin-isozyme 1 |
| MW: | 37.5 kD |
From 266.00€
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Anti-SBT6.1
Item number: CSB-PA877556XA01DOA.100
Protein function: Serine protease that catalyzes the first step (site-1 cleavage) in the proteolytic activation of various factors, prior to site-2 cleavage. Part of a regulated intramembrane proteolysis (RIP) cascade. Cleaves BZIP17 and BZIP28 after the Arg-Arg-Ile-Leu (RRIL) motif. May cleave BZIP49 after the RRIL...
| Keywords: | Anti-AtS1P, Anti-AtSBT6.1, Anti-Site-1 protease, Anti-Subtilase subfamily 6 member 1, Anti-Subtilisin-like protease... |
| Application: | ELISA, WB |
| Species reactivity: | Arabidopsis thaliana |
From 167.00€
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MBTPS1 Protein, Human, Recombinant (His & SUMO)
Item number: TGM-TMPH-01661-10ug
Description: MBTPS1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 37.5 kDa and the accession number is Q14703.
| Keywords: | KIAA0091 , SKI1 , Endopeptidase S1P , S1P , Membrane-bound transcription factor site-1 protease , Subtilisin/kexin-isozyme... |
| MW: | 37.5 kD |
From 99.00€
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Human S1P (Sphingosine 1 Phosphate) ELISA Kit (HUFI04787)
Item number: G-HUFI04787.96
Human S1P (Sphingosine 1 Phosphate) ELISA Kit from Assay Genie is a pre-coated immunoassay with a high sensitivity and broad range and has been designed to measure Human S1P (Sphingosine 1 Phosphate) in serum, plasma & cell culture supernatant samples. The Human S1P (Sphingosine 1 Phosphate) ELISA Kit accurately...
| Keywords: | SKI-1, Endopeptidase S1P, Subtilisin/kexin-isozyme 1, Membrane-bound transcription factor site-1 protease |
| Application: | Competitive ELISA |
| Species reactivity: | human |
698.00€
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