- Search results for K08367
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54 products were found matching "K08367"!
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Item number: ARG43820.100
Protein function: Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB...
Keywords: | Anti-AML1, Anti-RUNX1, Anti-CBF-alpha-2, Anti-CBF-alpha-2, Anti-PEA2-alpha B, Anti-PEA2-alpha B, Anti-PEBP2-alpha B,... |
Application: | IHC (paraffin), WB |
Host: | Rabbit |
Species reactivity: | human, mouse |
624.00€
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Item number: ARG57484.100
Protein function: CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. The alpha subunit binds DNA and appears to have a role in the development of normal hematopoiesis....
Keywords: | Anti-AML1, Anti-RUNX1, Anti-CBF-alpha-2, Anti-PEA2-alpha B, Anti-PEBP2-alpha B, Anti-Oncogene AML-1, Anti-Acute myeloid... |
Application: | WB, IHC (paraffin), ICC, IF, IP, FC |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
624.00€
*
Item number: Cay16771-10
Core binding factors (CBFs) are heterodimeric transcription factors consisting of a DNA-binding CBFalpha component (a RUNX protein) and an enhancer of binding, CBFbeta. CBF dimers have central roles in hematopoiesis and, when dysfunctional, in leukemias. CBFbeta inhibitor is a small molecule that binds to CBFbeta...
Keywords: | Core Binding Factor-beta Inhibitor, 5-ethyl-4-(4-methoxyphenyl)-2-thiazolamine |
Application: | CBFbeta-Runx1 interaction inhibitor |
CAS | 493028-20-9 |
MW: | 234.3 D |
From 97.00€
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Item number: 100-401-V33
Anti-AML1-ETO Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. This product reacts with human AML1-ETO. Cross reactivity with AML1-ETO from other sources is not known. Protein function: CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers...
Keywords: | Anti-AML1, Anti-RUNX1, Anti-CBF-alpha-2, Anti-PEA2-alpha B, Anti-PEBP2-alpha B, Anti-Oncogene AML-1, Anti-Acute myeloid... |
Application: | ELISA, ChIP, WB |
Host: | Rabbit |
Species reactivity: | human |
684.00€
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Item number: LKT-O6932.100
Oridonin has potent anti-tumor activity. Oridonin targets AE (AML1-ETO) oncoprotein. Exposure to oridonin induces apoptosis in AE-bearing leukemic cells through the activation of intrinsic apoptotic pathway and triggering a caspase-3-mediated degradation of AE at D188.
Keywords: | Isodonol, 7a,20-Epoxy-1a,6b,7,14-tetrahydroxy-Kaur-16-en-15-one |
Application: | Apoptosis inducer |
CAS | 28957-04-2 |
MW: | 364.43 D |
From 121.00€
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Item number: NSJ-R31576
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Runt-related transcription factor 1, also known as AML1 or CBFA2, is a protein that in humans is encoded by the RUNX1 gene. It belongs to the Runt-related transcription factor (RUNX) family of genes which are also called Core binding factor alpha (CBFa). RUNX1...
Keywords: | Anti-AML1, Anti-RUNX1, Anti-CBF-alpha-2, Anti-PEA2-alpha B, Anti-PEBP2-alpha B, Anti-Oncogene AML-1, Anti-Acute myeloid... |
Application: | WB, IHC (paraffin), (IF) |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
755.00€
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Item number: NSJ-F53076-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. The alpha subunit binds DNA and appears to have a role in the development...
Keywords: | Anti-AML1, Anti-RUNX1, Anti-CBF-alpha-2, Anti-PEA2-alpha B, Anti-PEBP2-alpha B, Anti-Oncogene AML-1, Anti-Acute myeloid... |
Application: | WB, ELISA |
Host: | Rabbit |
Species reactivity: | human |
From 326.00€
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Item number: NSJ-F48224-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The RUNX1 protein represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Protein...
Keywords: | Anti-AML1, Anti-RUNX1, Anti-CBF-alpha-2, Anti-PEA2-alpha B, Anti-PEBP2-alpha B, Anti-Oncogene AML-1, Anti-Acute myeloid... |
Application: | WB, IHC, IF, FC, ELISA |
Host: | Rabbit |
Species reactivity: | human |
From 326.00€
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Item number: E-AB-60579.120
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this...
Keywords: | Anti-AML1, Anti-RUNX1, Anti-CBF-alpha-2, Anti-PEA2-alpha B, Anti-PEBP2-alpha B, Anti-Oncogene AML-1, Anti-Acute myeloid... |
Application: | WB, IHC, IF |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 198.00€
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Item number: ABE-35-1706-50
CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. The a subunit binds DNA and appears to have a role in the development of normal hematopoiesis. Isoform AML-1L...
Keywords: | Anti-AML1, Anti-RUNX1, Anti-CBF-alpha-2, Anti-PEA2-alpha B, Anti-PEBP2-alpha B, Anti-Oncogene AML-1, Anti-Acute myeloid... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human |
574.00€
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Item number: ARG40556.100
Protein function: Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'-TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is...
Keywords: | Anti-AML1, Anti-RUNX1, Anti-CBF-alpha-2, Anti-PEA2-alpha B, Anti-PEBP2-alpha B, Anti-Oncogene AML-1, Anti-Acute myeloid... |
Application: | FC, ICC, IF, IHC (paraffin), WB |
Host: | Rabbit |
Species reactivity: | human |
584.00€
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Item number: ARG41229.50
Protein function: Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'-TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is...
Keywords: | Anti-AML1, Anti-RUNX1, Anti-CBF-alpha-2, Anti-PEA2-alpha B, Anti-PEBP2-alpha B, Anti-Oncogene AML-1, Anti-Acute myeloid... |
Application: | IHC (paraffin), WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
520.00€
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