65 products were found matching "K08069"!

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human VNN1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human VNN1. Next,...

Pantothenate-AMC is a fluorogenic substrate for vanin-1, an enzyme involved in the recycling of L-pantothenic acid. Upon enzymatic cleavage by vanin-1, 7-amino-7-methylcoumarin (AMC) is released and its fluorescence can be used to quantify vanin-1 activity. AMC displays excitation/emission maxima of 340-360/440-460...

Anti-WAPL antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. WAPL antibody is human, mouse and rat reactive. At least four isoforms of WAPL are known to exist. Protein function: Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus...

Protein function: Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine. [The UniProt Consortium]

This gene encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat VNN1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat VNN1. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse VNN3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse VNN3. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse VNN1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse VNN1. Next,...

RR6 is an inhibitor of the pantetheinase vanin-1 (IC50 = 0.54 µM for the recombinant human enzyme) and is a derivative of the CoA precursor D-pantothenic acid (Cay-17288). It is selective for vanin-1 over biotinidase, cathepsin B, cathepsin L, and papain (IC50s = >200 µM for all). RR6 is active against P. falciparum...

PFI-653 is an inhibitor of the pantetheinase vanin-1 (IC50 = 6.85 nM for the human enzyme). In vivo, PFI-653 (50 mg/kg) prevents reductions in body weight, as well as reduces disease severity and serum vanin-1 levels in a mouse model of colitis induced by dextran sulfate sodium (DSS, Cay-23250). See the Structural...

Description: Vanin-1-IN-1 (VUN34002) is an vanin-1 enzyme inhibitor. Target: Others. Smiles: O=C(N1CCC2(C1)CCOCC2)c1cnc(NCc2cnccn2)nc1. References: Agustin Casimiro-Garcia, et al. Novel pyrimidine carboxamides as inhibitors of vanin-1 enzyme. WO2018011681A1.