109 products were found matching "K07986"!

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. ULBP1 antibody is designed to detect UL16-binding protein 1, a stress-induced ligand for the NKG2D receptor on natural killer (NK) cells and certain T cells. ULBP1 is a member of the MHC class...

Protein function: Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity. [The UniProt Consortium]

Protein function: Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity. [The UniProt Consortium]

Cell surface proteins major histocompatibility complex (MHC) class I-related chain A (MICA) and UL16-binding proteins (ULBP) 1, 2, and 3 are up-regulated upon infection or tumor transformation and can activate human natural killer (NK) cells.

ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway, mediating natural killer cell cytotoxicity.

ULBP2 expression was however linked to expression of mature CD57() NK cells. In particular, expression of ULBP2 was strongest on those NK cells that had evidence of recent activation and proliferation. We suggest that ULBP2 could be used to identify recently activated 'mature' NK cells.

ULBP-1, or UL16-binding protein 1, is a protein that plays a significant role in the immune system, particularly in the recognition and elimination of abnormal cells, such as those found in cancer. It is a ligand for the NKG2D receptor, which is expressed on the surface of natural killer (NK) cells and certain T...

ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway, mediating natural killer cell cytotoxicity.

Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity.UL16-binding proteins (ULBPs) are unusual members of the extended MHC class I superfamily. They do not contain the alpha 3 domain and lack a transmembrane domain. Protein function: Binds and activates the KLRK1/NKG2D receptor,...

Anti-Unc93b Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Multiple isoforms of Unc93a are known to exist. This antibody will not cross-react with Unc93a. Protein function: Ligand for the KLRK1/NKG2D receptor, together with at least ULBP2 and ULBP3. ULBPs activate...

Human ULBP1, also known as RAET1I, N2DL-1, NKG2DL1, UL16 binding protein 1. GenBank Accession No. NM_025218, a.a. 26-215, fused at the C-terminus of the Fc portion of Human IgG1, with C-terminal Avi-tag(TM), expressed in a HEK293 cell expression system. MW = 51 kDa. This protein runs at a higher molecular weight due...