66 products were found matching "K07828"!

Erastin, named for eradicator of RAS and small T (ST) antigen-expressing cells, is a ferroptosis inducer. It induces ferroptotic cell death in vitro, an effect that can be blocked by the ferroptosis inhibitors ciclopirox olamine, Trolox (Cay-10011659), ferrostatin-1 (Cay-17729), U-0126 (Cay-70970), cycloheximide...

NRas is a key mediator of the mitogenic pathway in normal cells and in cancer cells. Its dynamics and nanoscale organization at the plasma membrane (PM) facilitate its signaling. NRas activity is mediated and regulated by its dynamic interactions with functional (Grb2, BRAF, NF1, and GPI-nucleated) clusters at the PM.

This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine...

Human NRAS, also known as GTPase NRas and NS6, GenBank Accession No. NM_002524, a.a. 2-186, with Q61L mutation and N-terminal His-tag, expressed in a Baculovirus infected Sf9 cell expression system. MW=22 kDa.

Human NRAS, also known as GTPase NRas and NS6, GenBank Accession No. NM_002524, a.a. 2-186, with Q61K mutation and N-terminal His-tag, expressed in a Baculovirus infected Sf9 cell expression system. MW=22 kDa.

Association of Ras protein with the inner surface of the plasma membrane is required for Ras signaling activity. Farnesyl thiosalicylic acid (FTS) amide is an FTS derivative with an amide added to the carboxyl group. FTS amide inhibits the growth of PANC-1 and U87 tumor cells with IC50 values of 20 and 10 µM,...

Human NRAS also known as GTPase NRas and NS6, GenBank Accession No. NM_002524, a.a. 2-186, with Q61H mutation and N-terminal His-tag, expressed in a Baculovirus infected Sf9 cell expression system. MW=22 kDa.

Protein function: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. [The UniProt Consortium]

Protein function: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. [The UniProt Consortium]

Protein function: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. [The UniProt Consortium]

Protein function: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. [The UniProt Consortium]

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Neuroblastoma RAS Protein function: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. [The UniProt Consortium]