22 products were found matching "K07424"!

alpha-Hydroxymidazolam is the major metabolite of the anesthetic, midazolam. It is produced rapidly by the actions of hepatic cytochrome P450 3A and has been shown to be equipotent to midazolam.Formal Name: 8-chloro-6-(2-fluorophenyl)-4H-imidazo[1,5-a][1,4]benzodiazepine-1-methanol. CAS Number: 59468-90-5. Synonyms:...

A potent and selective dual inhibitor of mesenchymal-epithelial transition factor (c-MET) kinase and anaplastic lymphoma kinase (ALK).

11alpha-hydroxy Testosterone is a metabolite of testosterone, produced by the cytochrome P450 (CYP) isoform CYP3A. It can also be generated from testosterone by a mutant of CYP107A1 and from 11alpha-hydroxy progesterone by the fungus B. bassiana. The biological activity of this metabolite has not been...

Desmethyl ranolazine is a metabolite of the antianginal agent ranolazine (Cay-15604). It is formed from ranolazine by the cytochrome P450 (CYP) isoform CYP3A.Formal Name: N-(2,6-dimethylphenyl)-4-[2-hydroxy-3-(2-hydroxyphenoxy)propyl]-1-piperazineacetamide. CAS Number: 172430-45-4. Synonyms: CVT-2514, RS 88390....

cis-9,10-Epoxyoctadecanoic acid is an epoxy fatty acid. It is an oxidation product of oleic acid formed by the cytochrome P450 (CYP) isoforms CYP2C and CYP3A. It has been found in the fungus P. carinii isolated from the lungs of rats in a model of P. carinii-induced pneumonia. cis-9,10-Epoxyoctadecanoic acid has...

CVT-2738 is an active metabolite of the antianginal agent ranolazine (Cay-15604). It is formed from ranolazine by the cytochrome P450 (CYP) isoform CYP3A. CVT-2738 (100 mg/kg) inhibits increases in T-wave height and the RR interval in a mouse model of myocardial ischemia induced by isoprenaline (isoproterenol,...

Rabeprazole sulfone is a metabolite of the proton pump inhibitor rabeprazole (Cay-14939). It is formed from rabeprazole by the cytochrome P450 (CYP) isoform CYP3A. Rabeprazole sulfone has also been found as an impurity in bulk preparations of rabeprazole.Formal Name:...

Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 1-503aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: MELIPNLSIE TWVLLVTSLV LFYIYGTYSH GLFKKLGIPG PKPLPLLGTI FNYYDGMWKF DEDCYKKYGK IWGFYEGPQP ILAIMDPEII KIVLVKECYS VFTNRRFFGP...

Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 1-504aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MNLFSALSLD TLVLLAIILV LLYRYGTCTH GLFKKQGIPG PKPLPFLGTV LNYYKGLWKF DMECYEKYGK TWGLFDGQIP LFVITDPETI KNVLVKECFS VFTNRQDFFP VGIMSKSISL AKDEEWKRYR...

Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 1-503aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: MDLIPNFSME TWMLLATSLV LLYLYGTHSH GIFKKLGIPG PKPLPFLGTI LAYQKGFWEC DIQCHKKYGK MWGLYDGRQP VLAITDPDII KTVLVKECYS TFTNRRRFGP VGILKKAISI SENEEWKRIR...

Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 1-504aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: MDLVSALSLE TWVLLAISLV LLYRYGTRKH ELFKKQGIPG PKPLPFLGTV LNYYKGLWKF DMECYKKYGK TWGLFDGQTP LLAVTDPETI KNVLVKECFS VFTNRRDFGP...

Description: Desmethyl ranolazine is a metabolite of the antianginal agent ranolazine .1It is formed from ranolazine by the cytochrome P450 (CYP) isoform CYP3A. Target: Others. Smiles: Cc1cccc(C)c1NC(=O)CN1CCN(CC(O)COc2ccccc2O)CC1. References: Wang, Y., Chen, X., Sun, Z., et al.Development and validation of a...