52 products were found matching "K07410"!

Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. CYP1B1 antibody detects Cytochrome P450 1B1, a member of the cytochrome P450 superfamily of monooxygenases involved in xenobiotic metabolism, steroid synthesis, and carcinogen activation. The UniProt recommended name is Cytochrome P450 1B1...

4-Hydroxyestradiol is a catechol estrogen and minor metabolite of estrogen. 4-Hydroxyestradiol is formed from estrogen by the cytochrome P450 (CYP) isoform CYP1B1. Production of 4-hydroxyestradiol is increased in microsomes prepared from human mammary adenocarcinoma and fibroadenoma microsomes compared with...

CYP1B1 is mainly an extrahepatic enzyme which oxidatively metabolizes both endogenous (steroids, eicosanoids) and exogenous xenobiotics such aspolyaromatic hydrocarbons. TMS is a potent and selective inhibitor of CYP1B1, with an IC50 of 6 nM. It is 50-fold selective for the inhibition of CYP1B1 versus CYP1A1, making...

Diosmetin is a flavonoid that has been found in citrus fruits and has diverse biological activities. It inhibits the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1B1 (Kis = 89 and 16 nM, respectively). Diosmetin prevents increases in erythrocyte reactive oxygen species (ROS) and malondialdehyde (MDA) levels induced...

DMU2139 is an inhibitor of the cytochrome P450 (CYP) isoform CYP1B1 (IC50 = 0.009 µM). It is selective for CYP1B1 over CYP1A1, CYP1A2, CYP3A4, and CYP2D6 (IC50s = 0.795, 1.2, 10.6, and 5 µM, respectively). DMU2139 enhances cisplatin-induced cell death in HEK293 cells overexpressing CYP1B1.Formal Name:...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Cytochrome P450 1B1 is an enzyme that in humans is encoded by the CYP1B1 gene. CYP1B1 belongs to the the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and...

In 1X PBS, pH 7.4, with 0.09% sodium azide. CYP1B1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme localizes to the endoplasmic...

Protein function: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, retinoid and xenobiotics. Preferentially oxidizes...

Alizarin is a small molecule inhibitor of cytochrome P450 isoforms CYP1A1, CYP1A2, and CYP1B1 (IC50s = 6.2, 10, and 2.7 µM, respectively). Alizarin acts as an antioxidant against iodophenol-derived phenoxyl radicals, superoxide anion radicals, and lipid peroxidation in rat liver microsomes. It also reduces hepatic...

Protein function: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, retinoid and xenobiotics. Preferentially oxidizes...