43 products were found matching "K07376"!

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PRKG1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PRKG1. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse PRKG1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse PRKG1. Next,...

1-Aminoguanosine-3',5'-monophosphate (1-amino cGMP) is a derivative of the secondary messenger cGMP (Cay-18821) and a substrate for cGMP-dependent protein kinase.Formal Name: 1-amino-cyclic 3',5'-(hydrogen phosphate) guanosine, monosodium salt. CAS Number: 1380911-23-8. Synonyms: 1-amino cGMP. Molecular Formula:...

The activity of cGMP-dependent protein kinase (PKG) is controlled by factors that elevate cellular cGMP, like nitric oxide (NO), and by those that reduce cGMP levels, like certain phosphodiesterases. KT 5823 is a potent, selective inhibitor of cGMP-dependent protein kinase (PKG) (in vitro IC50 = 234 nM). KT 5823 is...

8-bromo Cyclic GMP (8-bromo cGMP) is a cell-permeable analog of cGMP that exhibits greater resistance to hydrolysis by phosphodiesterases than its parent compound. It preferentially activates cGMP-dependent protein kinase. At 1 µM-0.1 mM, 8-bromo cGMP can inhibit acetylcholine-induced increases in intracellular...

PKG inhibitor is a specific cGMP-dependent PKG inhibitor (Ki = 86 µM). This synthetic peptide is a nonphosphorylatable analog of a substrate corresponding to the serine-32 phosphorylation site in histone H2B. PKG inhibitor has been reported to block cGMP-dependent NMDA potentiation and nitric oxide-induced...

HA-100 is an isoquinoline compound with an added piperazinylsulfonyl group that acts as an inhibitor of protein kinases (PKs), including PKA, PKC, and PKG (IC50s = 8, 12, and 4 µM, respectively). It less effectively blocks the activity of myosin light chain kinase (IC50 = 240 µM).Formal Name:...

Dibutyryl-cyclic GMP (dibutyryl-cGMP) is a cell-permeable, cGMP analog that activates cGMP-dependent protein kinase. It has been used in a wide variety of research applications to mimic cGMP interactions and effects on different biological molecules.Formal Name: N-(1-oxobutyl)-cyclic 3',5'-(hydrogen phosphate)...

A K252 derivitive.

cGMP dependent Human PKG1alpha (GenBank Accession No. NM_001098512), full length with N-terminal His tag, MW = 80 kDa, expressed in Baculovirus infected Sf9 cell expression system. Enzyme reaction is conducted in a buffer containing 50 mM HEPES (pH7.5), 10 mM MgCl2, 1 mM EGTA, 200 µM ATP, 0.01% Brij-35, and 2 µM...

Active human PKG1beta (GenBank Accession No. NM_006258), full length with N-terminal His tag, MW = 78 kDa, expressed in Baculovirus infected Sf9 cell expression system.

Cyclic GMP (cGMP) is a second messenger that is biosynthesized from GTP by guanylate cyclases. Activators of guanylate cyclases include nitric oxide and natriuretic peptides. cGMP activates protein kinase G (PKG) and modulates ion channel conductance, with signaling affecting diverse processes including smooth...