42 products were found matching "K07369"!

The Fluorogenic MALT1 Assay Kit is designed to measure MALT1 activity for screening and profiling applications, in a homogeneous assay with no time-consuming washing steps.

Synthetic. Soluble in water. Selective cell permeable and irreversible MALT1 inhibitor. Inhibits NF-?B-dependent gene expression and affects the growth, proliferation and survival of activated B cell-like diffuse large B cell lymphomas (ABC-DLBCL) and germinal center B cell like diffuse large B cell lymphoma...

White to off-white solid. Soluble in DMSO (30mg/ml) or ethanol (5mg/ml). Highly potent and selective irreversible MALT1 inhibitor (IC50=5.8&mu,M). Binds directly to MALT1 and suppresses protease function, Decreases NF-kappaB activity induced by MALT1. Inhibits cell proliferation and MALT1-mediated cleavage activity....

Z-VRPR-FMK is a selective, irreversible inhibitor of the paracaspase mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1), an endopeptidase that targets BCL10 and reduces NF-kappaB activation in lymphocytes at 12.5 to 75 µM. Other MALT1 substrates that may be affected by Z-VRPR-FMK are TNFAIP3...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Mucosa-associated lymphoid tissue lymphoma translocation protein 1, also called MLT or Paracaspase, is a protein that in humans is encoded by the MALT1 gene. This gene has been found to be recurrently rearranged in chromosomal translocation with two other genes...

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Mucosa associated lymphoid tissue lymphoma translocation gene 1 Protein function: Enhances BCL10-induced activation of NF-kappa-B. Involved in nuclear export of BCL10. Binds to TRAF6, inducing...

0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The...

1 mg/ml in sterile PBS, BSA free, sodium azide free. Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation...

Protein function: Enhances BCL10-induced activation of NF-kappa-B. Involved in nuclear export of BCL10. Binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. Has ubiquitin ligase activity. MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced...

Protein function: Enhances BCL10-induced activation of NF-kappa-B. Involved in nuclear export of BCL10. Binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. Has ubiquitin ligase activity. MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced...

MI 2 is an inhibitor of the paracaspase MALT1 with an IC50 value of 5.84 µM in a fluorescence assay. It inhibits the growth of MALT1-dependent activated B cell-like diffuse large B cell lymphoma (ABC-DLBCL) cell lines (GI50s = 0.2, 0.5, 0.4, and 0.4 µM for HBL-1, TMD8, OCI-Ly3, and OCI-Ly10 cells, respectively). MI...

Mouse MALT1 also known as IMD12, MLT, MLT1, PCASP1, and MALT1 paracaspase, GenBank Accession No. NM_172833, a.a. 2-832 (end), and expressed in a Baculovirus infected Sf9 cell expression system. MW = 93 kDa.