118 products were found matching "K06531"!

For flow cytometry, Western blotting and immunohistology dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10. Fixation with PFA or acetone/methanol is recommended.

Human secreted CD112, also known as Nectin-2, Herpes virus entry mediator B, HVEB, PVRL2, and PRR2, GenBank Accession No. NM_002856, a.a. 32-360 expressed in a HEK293 cell expression system, with C-terminal His and Avi(TM) tags, this protein is enzymatically biotinylated using Avi-tag(TM) technology. MW = 38.3 kDa....

CD112 (also called Nectin-2 or poliovirus receptor-related 2 protein) is a type I transmembrane glycoprotein and a member of the Ig gene superfamily (IGSF). CD112/Nectin-2 functions as an adhesion molecule involved in the formation of cell junctions and interactions with other Nectin-family molecules. Nectin-2 is a...

Human secreted CD112, also known as Nectin-2, Herpes virus entry mediator B, HVEB, PVRL2, and PRR2, GenBank Accession No. NM_002856, a.a. 32-360 with a C-terminal His-tag, expressed in a HEK293 cell expression system. MW = 36.4 kDa (monomer). This protein runs at a higher MW by SDS-PAGE due to glycosylation.

Human secreted CD112, also known as Nectin-2, Herpes virus entry mediator B, HVEB, PVRL2, and PRR2, GenBank Accession No. NM_002856, a.a. 32-360 expressed in a HEK293 cell expression system, with C-terminal Fc-Fusion-Avi tag, this protein is enzymatically biotinylated using Avi-tag(TM) technology. MW = 64 kDa. This...

This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is...

Protein function: Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG,...

Protein function: Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG,...

Nectin-2, also known as CD112, is a member of the nectin family of adhesion molecules that mediates the formation of adherens junctions and regulates immune cell activation. It contains an N-terminal extracellular domain with three immunoglobulin-like (Ig-like) loops, C1-like and C2 domains that mediate...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Nectin-2 is a 60 or 65 kDa type I TM glycoprotein that is found on a variety of cell types. It is mapped to 19q13.32. This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one...

Protein function: Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG,...