86 products were found matching "K06276"!

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Mouse PDPK1 (Phosphoinositide Dependent Protein Kinase 1) ELISA Kit
Mouse PDPK1 (Phosphoinositide Dependent Protein Kinase 1)...

Item number: ELK-ELK6179.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse PDPK1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse PDPK1. Next,...
Keywords: Pdk1, mPDK1, Pdpk1, EC=2.7.11.1, 3-phosphoinositide-dependent protein kinase 1
Application: ELISA
Species reactivity: mouse
365.00€ * From 328.50€ *
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GSK2334470
GSK2334470

Item number: Cay18095-5

3-Phosphoinositide-dependent protein kinase 1 (PDK1) is a serine-threonine kinase that plays an important role in growth factor signaling by phosphorylating and activating a group of kinases, including protein kinase (PK)B, PKA, and certain isoforms of PKC. GSK2334470 is an inhibitor of PDK1 (IC50 = ~10 nM) that...
Keywords: (3S,6R)-1-[6-(3-amino-1H-indazol-6-yl)-2-(methylamino)-4-pyrimidinyl]-N-cyclohexyl-6-methyl-3-piperidinecarboxamide
Application: PDPK1 inhibitor
CAS 1227911-45-6
MW: 462.6 D
From 102.00€ *
Review
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6BIO
6BIO

Item number: AG-CR1-0056-M001

Phosphoinositide-dependent kinase 1 (PDK1) inhibitor, Potent, reversible and ATP-competitive glycogen synthase kinase-3alpha/beta (GSK-3alpha/beta) inhibitor, JAK/STAT3 signaling inhibitor, Apoptosis inducer, Potent antiproliferative agent in malignant lymphoid cell.
Keywords: 2’Z,3’E)-6-Bromoindirubin-3’-oxime
Application: PDPK1 inhibitor
CAS 667463-62-9
MW: 356,2 D
39.00€ * From 35.10€ *
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Xanthohumol
Xanthohumol

Item number: Cay15399-10

Xanthohumol is a natural prenylated chalcone isolated from the hop plant, H. lupulus. Xanthohumol and its metabolites induce protective detoxification enzymes, at least in part via the nuclear factor erythroid-2-related factor 2 pathway. It inhibits phosphoinositide-dependent kinase 1 (IC50 = 6.6 µM) but not PKC in...
Keywords: (2E)-1-[2,4-dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one
Application: PDPK1 inhibitor
CAS 6754-58-1
MW: 354.4 D
From 32.00€ *
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BX-795
BX-795

Item number: Cay14932-5

BX-795 is a multi-kinase inhibitor that is an ATP-competitive inhibitor of 3-phosphoinositide-dependent protein kinase 1 (PDK1) and TANK-binding kinase 1 (TBK1, IC50s = 6 and 11 nM, respectively). It also inhibits the CAMK family kinases AMPK-related kinase 5 (NUAK1, IC50 = 5 nM) and microtubule affinity-regulating...
Keywords: N-[3-[[5-iodo-4-[[3-[(2-thienylcarbonyl)amino]propyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide
Application: PDPK1 inhibitor
CAS 702675-74-9
MW: 591.5 D
From 109.00€ *
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GSK2334470
GSK2334470

Item number: LKT-G7344.5

GSK2334470 is a potent 3-phosphoinositide-dependent protein kinase (PDK1) inhibitor (IC50 ~ 10 nM).
Keywords: GSK-2334470,...
Application: PDPK1 inhibitor
CAS 1227911-45-6
MW: 462.59 D
From 90.00€ *
Review
BX-912
BX-912

Item number: Cay14708-1

3-Phosphoinositide-dependent protein kinase 1 (PDK1) is a serine-threonine kinase that phosphorylates and activates a range of other kinases, including protein kinase (PK)B, PKA, and certain isoforms of PKC. BX-912 is a potent, ATP-competitive inhibitor of PDK1 (IC50 = 26 nM). It less effectively inhibits a panel of...
Keywords: N-[3-[[5-bromo-4-[[2-(1H-imidazol-5-yl)ethyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide
Application: PDK1 inhibitor
CAS 702674-56-4
MW: 471.4 D
From 61.00€ *
Review
BX-795
BX-795

Item number: SYN-1026-M001

Soluble in DMSO or ethanol. BX795 was initially developed as a PDK1 inhibitor (direct competitive inhibitor IC(50) 11nM for PDK1) and has been shown to be a potent and relatively specific inhibitor of TBK1 and IKK-epsilon. It blocks the phosphorylation, nuclear translocation, and transcriptional activity of...
Keywords: BX795
Application: PDPK1 inhibitor
CAS 702675-74-9
MW: 591,5 D
From 100.00€ *
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OSU03012
OSU03012

Item number: Cay10008005-10

Cyclooxygenase-2 (COX-2) appears to play a significant role in the development and progression of cancer and COX-2 inhibitors such as celecoxib exhibit anti-cancer activity. OSU03012 is an analog of celecoxib that exhibits anti-cancer activity in a COX-2-independent manner via inhibition of the phosphatidyl...
Keywords: 2-amino-N-[4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-acetamide
Application: PDK1 (PDPK1) inhibitor
CAS 742112-33-0
MW: 460.5 D
From 98.00€ *
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Anti-PDK1
Anti-PDK1

Item number: ARG51005.100

Protein function: Serine/threonine kinase which acts as a master kinase, phosphorylating and activating a subgroup of the AGC family of protein kinases. Its targets include: protein kinase B (PKB/AKT1, PKB/AKT2, PKB/AKT3), p70 ribosomal protein S6 kinase (RPS6KB1), p90 ribosomal protein S6 kinase (RPS6KA1, RPS6KA2...
Keywords: Anti-PDK1, Anti-hPDK1, Anti-PDPK1, EC=2.7.11.1, Anti-3-phosphoinositide-dependent protein kinase 1
Application: ICC, IF, IHC (paraffin), WB
Host: Rabbit
Species reactivity: human, mouse, rat
From 436.00€ *
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Anti-phospho-PDK1 (Ser241)
Anti-phospho-PDK1 (Ser241)

Item number: ARG51509.100

Protein function: Serine/threonine kinase which acts as a master kinase, phosphorylating and activating a subgroup of the AGC family of protein kinases. Its targets include: protein kinase B (PKB/AKT1, PKB/AKT2, PKB/AKT3), p70 ribosomal protein S6 kinase (RPS6KB1), p90 ribosomal protein S6 kinase (RPS6KA1, RPS6KA2...
Keywords: Anti-phospho-PDK1, Anti-phospho-hPDK1, Anti-phospho-PDPK1, EC=2.7.11.1, Anti-phospho-3-phosphoinositide-dependent protein...
Application: ICC, IF, IHC (paraffin), WB
Host: Rabbit
Species reactivity: human, mouse, rat
From 436.00€ *
Review
Anti-PDK1
Anti-PDK1

Item number: A302-130A

Protein function: Serine/threonine kinase which acts as a master kinase, phosphorylating and activating a subgroup of the AGC family of protein kinases. Its targets include: protein kinase B (PKB/AKT1, PKB/AKT2, PKB/AKT3), p70 ribosomal protein S6 kinase (RPS6KB1), p90 ribosomal protein S6 kinase (RPS6KA1, RPS6KA2...
Keywords: Anti-PDK1, Anti-hPDK1, Anti-PDPK1, EC=2.7.11.1, Anti-3-phosphoinositide-dependent protein kinase 1
Application: WB, IP
Host: Rabbit
Species reactivity: human, mouse
From 164.00€ *
Review
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