38 products were found matching "K06128"!
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ML-211
Item number: Cay17630-1
Lysophospholipase 1 (LYPLA1) is a protein palmitoyl thioesterase responsible for depalmitoylation of the oncogene HRas. Palmitoylation of such oncogenes is thought to be required for trafficking and malignant transformation, making LYPLA1 a target for downregulating oncogenic signaling. ML-211 is a carbamate-based...
| Keywords: | [4-(1,1-dimethylethyl)-1-piperidinyl][4-(hydroxydiphenylmethyl)-2H-1,2,3-triazol-2-yl]-methanone |
| Application: | LYPLA1 / LYPLA2 inhibitor |
| CAS | 2205032-89-7 |
| MW: | 418.5 D |
From 56.00€
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ML-348
Item number: Cay18523-1
Lysophospholipase 1 (LYPLA1) is a protein palmitoyl thioesterase responsible for depalmitoylation of the oncogene HRas. Palmitoylation of such oncogenes is thought to be required for trafficking and malignant transformation, making LYPLA1 a target for downregulating oncogenic signaling. ML-348 is a reversible LYPLA1...
| Keywords: | CID 3238952, SID 160654487, N-[2-chloro-5-(trifluoromethyl)phenyl]-4-(2-furanylcarbonyl)-1-piperazineacetamide |
| Application: | Reversible LYPLA1 inhibitor |
| CAS | 899713-86-1 |
| MW: | 415.8 D |
From 49.00€
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Anti-LYPLA1
Item number: ATA-HPA050941.100
Protein function: Acts as a acyl-protein thioesterase (PubMed:19439193, PubMed:20418879). Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS (PubMed:20418879). Has depalmitoylating activity toward KCNMA1 (PubMed:22399288). Could also depalmitoylate ADRB2...
| Keywords: | Anti-APT1, Anti-APT-1, Anti-LPL-I, Anti-hAPT1, Anti-LYPLA1, Anti-LysoPLA I, EC=3.1.2.-, Anti-Lysophospholipase I,... |
| Application: | IHC |
| Host: | Rabbit |
| Species reactivity: | human |
From 369.00€
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Acyl-protein thioesterase 1 (Lypla1), mouse, recombinant
Item number: CSB-EP013268MO.1
Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 1-230aa. Protein Length: Full Length. Tag Info: N-terminal GST-tagged. Target Protein Sequence: MCGNNMSAPM PAVVPAARKA TAAVIFLHGL GDTGHGWAEA FAGIKSPHIK YICPHAPVMP VTLNMNMAMP SWFDIVGLSP DSQEDESGIK QAAETVKALI DQEVKNGIPS NRIILGGFSQ GGALSLYTAL TTQQKLAGVT...
| Keywords: | Apt1, APT-1, LPL-I, Lypla1, LysoPLA I, EC=3.1.2.-, Lysophospholipase I, Lysophospholipase 1, Acyl-protein thioesterase 1,... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | mouse |
| MW: | 51.7 kD |
From 292.00€
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Anti-LYPLA1
Item number: CSB-PA003181.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Keywords: | Anti-APT1, Anti-APT-1, Anti-LPL-I, Anti-hAPT1, Anti-LYPLA1, Anti-LysoPLA I, EC=3.1.2.-, Anti-Lysophospholipase I,... |
| Application: | ELISA, WB, IHC, IF |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 126.00€
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Anti-LYPLA1
Item number: CSB-PA076865.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Keywords: | Anti-APT1, Anti-APT-1, Anti-LPL-I, Anti-hAPT1, Anti-LYPLA1, Anti-LysoPLA I, EC=3.1.2.-, Anti-Lysophospholipase I,... |
| Application: | ELISA, WB |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
284.00€
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ML348
Item number: TGM-T3439-100mg
Description: ML348 (GNF-Pf-1127) is a selective, reversible inhibitor of lysophospholipase 1 (LYPLA1) with an IC50 of 210 nM. Target: Phospholipase, Others. Smiles: FC(F)(F)c1ccc(Cl)c(NC(=O)CN2CCN(CC2)C(=O)c2ccco2)c1. References: Adibekian A, et al. National Center for Biotechnology Information (US), 2010-.2013 Apr...
| Keywords: | GNF-Pf-1127 |
| Application: | Reversible LYPLA1 inhibitor |
| CAS | 899713-86-1 |
| MW: | 415.79 D |
From 38.00€
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ML-211
Item number: TGM-T8974-100mg
Description: ML-211 is a carbamate-based dual inhibitor of LYPLA1 (IC50 = 17 nM) and LYPLA2 (IC50 = 30 nM). Target: Others. Smiles: C(O)(C1=NN(C(=O)N2CCC(C(C)(C)C)CC2)N=C1)(C3=CC=CC=C3)C4=CC=CC=C4. References: Adibekian A , Martin B R , Chang J W , et al. Characterization of a Selective, Reversible Inhibitor of...
| Application: | LYPLA1 / LYPLA2 inhibitor |
| CAS | 2205032-89-7 |
| MW: | 418.53 D |
From 115.00€
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APT-1 Protein, Human, Recombinant (His)
Item number: TGM-TMPJ-00702-10ug
Description: Acyl-Protein Thioesterase 1 (APT-1) is lysophospholipase that belongs to the AB hydrolase 2 family. Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. APT-1 performs on biological membranes to regulate the multifunctional lysophospholipids....
| Keywords: | LPL1, LPL-I, APT-1, Acyl-Protein Thioesterase 1, Lysophospholipase 1, LYPLA1, hAPT1, Lysophospholipase I, LysoPLA I, APT1 |
| MW: | 25 kD |
From 122.00€
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NEW
![Anti-Lysophospholipase 1 [R03-3R1] Monoclonal Antibody](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg "Anti-Lysophospholipase 1 [R03-3R1] Monoclonal Antibody")
Anti-Lysophospholipase 1 [R03-3R1] Monoclonal Antibody
Item number: G-AGMB03121.100
Lysophospholipase 1 Monoclonal Antibody from Assay Genie is a high quality antibody for research use only. Protein Function: Acts as an acyl-protein thioesterase (PubMed:19439193, PubMed:20418879). Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS...
| Keywords: | Anti-LYPLA1, Anti-Lysophospholipase 1, Anti-Lysophospholipase I, Anti-Acyl-protein thioesterase 1, Anti-Palmitoyl-protein... |
| Application: | WB, ICC/IF, FC |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 134.00€
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Lypla1, Recombinant, Mouse, aa1-230, GST-Tag...
Item number: 374106.100
Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity toward KCNMA1. Has low lysophospholipase activity. Source: Recombinant protein corresponding to aa1-230 from mouse Lypla1, fused to GST-Tag at N-terminal, expressed in E....
| Keywords: | Apt1, APT-1, LPL-I, Lypla1, LysoPLA I, EC=3.1.2.-, Lysophospholipase I, Lysophospholipase 1, Acyl-protein thioesterase 1 |
| MW: | 51,7 |
From 690.00€
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Human APT-1, recombinant (N-6His)
Item number: NOV-C097.10ug
Recombinant Human Acyl-Protein Thioesterase 1 is produced by our E.coli expression system and the target gene encoding Met1-Asp230 is expressed with a 6His tag at the N-terminus. Protein function: Acts as a acyl-protein thioesterase (PubMed:19439193, PubMed:20418879). Hydrolyzes fatty acids from S-acylated cysteine...
| Keywords: | APT1, LPL-I, hAPT1, APT-1, LYPLA1, LysoPLA I, EC=3.1.2.-, Lysophospholipase 1, Lysophospholipase I, Acyl-protein... |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 26.83 kD |
From 105.00€
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