- Search results for K05856
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103 products were found matching "K05856"!
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Item number: Cay13198-1
The Src family of non-receptor tyrosine kinases regulate cell adhesion, growth, and differentiation through activation of multiple intracellular signaling pathways. Normally inactive, Src kinases are transiently activated during mitosis and constitutively activated by abnormal mutations. PP2 is a potent, reversible,...
Keywords: | AGL 1879, 3-(4-chlorophenyl)-1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
Application: | Tyrosine kinase inhibitor |
CAS | 172889-27-9 |
MW: | 301.8 D |
From 43.00€
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Item number: Cay14244-1
PP1 is a potent, reversible, ATP-competitive, and selective inhibitor of the Src family of protein tyrosine kinases. It inhibits p56lck (IC50 = 5 nM), p59fynT (IC50 = 6 nM), Hck (IC50 = 20 nM), and Src (IC50 = 170 nM) without significantly affecting the activity of EGFR kinase (IC50 = 250 nM), JAK2 (IC50 = 50 µM),...
Keywords: | AGL 1872, EI 275, 1-(1,1-dimethylethyl)-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
Application: | Tyrosine kinase inhibitor |
CAS | 172889-26-8 |
MW: | 281.4 D |
From 66.00€
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Item number: ARG51643.50
Protein function: Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T- cells in the thymus and in the function of mature T-cells. Plays a key role in T-cell antigen receptor (TCR)-linked signal transduction pathways. Constitutively associated with the...
Keywords: | Anti-phospho-LCK, Anti-phospho-LSK, Anti-phospho-p56-LCK, EC=2.7.10.2, Anti-phospho-Protein YT16,... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 436.00€
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Item number: Cay30618-5
PD 173955 is a tyrosine kinase inhibitor. It inhibits c-Src, Yes, and LCK (IC50s = 25, 22, and 5 nM, respectively), as well as Bcr-Abl and c-Kit (IC50s = 1-2 and 25 nM, respectively), and is selective for these kinases over the insulin receptor (InsR), alpha-FGFR, basic FGFR (bFGFR), PDGFR, and PKC. PD 173955 (5,000...
Keywords: | 6-(2,6-dichlorophenyl)-8-methyl-2-[[3-(methylthio)phenyl]amino]-pyrido[2,3-d]pyrimidin-7(8H)-one |
Application: | Tyrosine kinase inhibitor |
CAS | 260415-63-2 |
MW: | 443.4 D |
From 43.00€
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Item number: Cay32854-5
A-770041 is an inhibitor of LCK kinase (IC50 = 0.147 µM). It is selective for LCK over other Src family tyrosine kinases including Src, Fyn, Fgr, HCK, and Tie2 (IC50s = 9.05, 44.1, 14.1, 1.22, and >50 µM, respectively). A-770041 induces dephosphorylation of LCK by SHP-1, inactivating LCK, in IgE/antigen-stimulated...
Keywords: | N-[4-[1-[trans-4-(4-acetyl-1-piperazinyl)cyclohexyl]-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-2-methoxyphenyl]-1-methyl-1... |
Application: | LCK inhibitor |
CAS | 869748-10-7 |
MW: | 621.7 D |
From 77.00€
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-15 %
Discount Promotion
Item number: ABE-10-8003-100
Protein function: Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T- cells in the thymus and in the function of mature T-cells. Plays a key role in T-cell antigen receptor (TCR)-linked signal transduction pathways. Constitutively associated with the...
Keywords: | Anti-LCK, Anti-LSK, Anti-p56-LCK, EC=2.7.10.2, Anti-Protein YT16, Anti-Proto-oncogene Lck, Anti-Tyrosine-protein kinase... |
Application: | WB |
Host: | Mouse |
Species reactivity: | human |
149.00€
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From 126.65€
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Item number: AG-CN2-0006-M001
Lck (p56lck, lymphocyte specific tyrosine kinase) inhibitor, Antioxidant, DPPH radical scavenger. Isolated from marine fungus Arthrinium sp.
Keywords: | 2,3,6,8-Tetrahydroxy-1-methylxanthone |
Application: | Lck inhibitor |
CAS | 548740-86-9 |
MW: | 274,1 D |
132.00€
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Item number: ARG51824.100
Protein function: Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T- cells in the thymus and in the function of mature T-cells. Plays a key role in T-cell antigen receptor (TCR)-linked signal transduction pathways. Constitutively associated with the...
Keywords: | Anti-phospho-LCK, Anti-phospho-LSK, Anti-phospho-p56-LCK, EC=2.7.10.2, Anti-phospho-Protein YT16,... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 436.00€
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Item number: ARG54095.100
Protein function: Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T- cells in the thymus and in the function of mature T-cells. Plays a key role in T-cell antigen receptor (TCR)-linked signal transduction pathways. Constitutively associated with the...
Keywords: | Anti-LCK, Anti-LSK, Anti-p56-LCK, EC=2.7.10.2, Anti-Protein YT16, Anti-Proto-oncogene Lck, Anti-Tyrosine-protein kinase... |
Application: | WB |
Host: | Mouse |
Species reactivity: | human |
624.00€
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Item number: ARG63058.100
Protein function: Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T- cells in the thymus and in the function of mature T-cells. Plays a key role in T-cell antigen receptor (TCR)-linked signal transduction pathways. Constitutively associated with the...
Keywords: | Anti-LCK, Anti-LSK, Anti-p56-LCK, EC=2.7.10.2, Anti-Protein YT16, Anti-Proto-oncogene Lck, Anti-Tyrosine-protein kinase... |
Application: | FC, ICC, IF, IP, WB |
Host: | Mouse |
Species reactivity: | human |
From 436.00€
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Item number: BPS-40470
Active recombinant full-length human LCK was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag. The gene accession number is NM_005356.
Keywords: | LCK, LSK, p56-LCK, EC=2.7.10.2, Protein YT16, Proto-oncogene Lck, Tyrosine-protein kinase Lck, Leukocyte C-terminal Src... |
Application: | Enzyme kinetics, inhibitor screening |
MW: | 84 kD |
540.00€
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Item number: NSJ-F53783-0.1ML
In ascites with 0.09% sodium azide. Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T-cells in the thymus and in the function of mature T-cells. Plays a key role in T-cell antigen receptor (TCR)-linked signal transduction pathways. Constitutively...
Keywords: | Anti-LCK, Anti-LSK, Anti-p56-LCK, EC=2.7.10.2, Anti-Protein YT16, Anti-Proto-oncogene Lck, Anti-Tyrosine-protein kinase... |
Application: | WB, ELISA |
Host: | Mouse |
Species reactivity: | human |
702.00€
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