107 products were found matching "K05856"!
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Lck Protein, Human, Recombinant (His)
Item number: TGM-TMPH-02275-100ug
Description: Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T-cells in the thymus and in the function of mature T-cells. Plays a key role in T-cell antigen receptor (TCR)-linked signal transduction pathways. Constitutively associated with the...
| Keywords: | T cell-specific protein-tyrosine kinase, Tyrosine-protein kinase Lck, LCK, Proto-oncogene Lck, Protein YT16, p56-LCK,... |
| MW: | 65.2 kD |
From 198.00€
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PP2
Item number: Cay13198-1
The Src family of non-receptor tyrosine kinases regulate cell adhesion, growth, and differentiation through activation of multiple intracellular signaling pathways. Normally inactive, Src kinases are transiently activated during mitosis and constitutively activated by abnormal mutations. PP2 is a potent, reversible,...
| Keywords: | AGL 1879, 3-(4-chlorophenyl)-1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Application: | Tyrosine kinase inhibitor |
| CAS | 172889-27-9 |
| MW: | 301.8 D |
From 44.00€
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Emodin
Item number: TGM-T2869-50mg
Description: Emodin (Frangula emodin) is a naturally occurring anthraquinone present in the roots and barks of numerous plants, exerts antiproliferative effects in Y cells that are regulated by different signaling pathways. Target: Autophagy, SARS-CoV, Casein Kinase. Smiles:...
| Keywords: | Frangula emodin |
| Application: | p56lck protein kinase inhibitor |
| CAS | 518-82-1 |
| MW: | 270.24 D |
From 45.00€
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Anomalin A
Item number: TGM-T124676-1mg
Description: Anomalin A is a useful organic compound for research related to life sciences. The catalog number is T124676 and the CAS number is 548740-86-9. Target: Others. Smiles: Cc1c(O)c(O)cc2oc3cc(O)cc(O)c3c(=O)c12
| Application: | Lck inhibitor |
| CAS | 548740-86-9 |
| MW: | 274.228 D |
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RK-24466
Item number: TGM-T16760-100mg
Description: RK-24466 (KIN 001-51) is a selective and potent Lck inhibitor, targeting Lck (64-509) and LckCD isoforms with IC50 values of less than 1 nM and 2 nM, respectively. Target: Src. Smiles: Nc1ncnc2n(cc(-c3ccc(Oc4ccccc4)cc3)c12)C1CCCC1. References: Seo HH, et al....
| Keywords: | KIN 001-51 |
| Application: | LCK inhibitor |
| CAS | 213743-31-8 |
| MW: | 370.45 D |
From 60.00€
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Lck inhibitor 2
Item number: TGM-T15725-1mL
Description: Lck inhibitor 2 is a bis-anilinopyrimidine inhibitor of tyrosine kinases including LCK, BTK, LYN, SYK, and TXK [IC50s: 13nM, 9nM, 3nM, 26nM, and 2nM for Lck, Btk, Lyn, Btk, and Txk respectively]. Target: Others. Smiles: Cc1ccc(O)cc1Nc1ccnc(Nc2cccc(c2)C(N)=O)n1. References: Bamborough, et al. Assessment...
| Application: | Lck inhibitor |
| CAS | 944795-06-6 |
| MW: | 335.36 D |
From 67.00€
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PD173955
Item number: TGM-T3063-100mg
Description: PD173955 is src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Src, Yes and Abl kinase, less potent for FGFRalpha and no activity on InsR and PKC. Target: Src, Apoptosis, Bcr-Abl. Smiles: CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1. References: Wisniewski D, et al. Cancer...
| Keywords: | PD 173955, PD-173955 |
| Application: | Tyrosine kinase inhibitor |
| CAS | 260415-63-2 |
| MW: | 443.35 D |
From 42.00€
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PCI 29732
Item number: TGM-T4337-100mg
Description: PCI 29732 is a selective and irreversible Btk inhibitor with IC50 of 8.2 nM in a FRET based biochemical enzymology assay. Target: BTK, BCRP, Others. Smiles: Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)C1CCCC1. References: Pan Z, etal. Discovery of selective irreversible inhibitors for Bruton's tyrosine...
| Keywords: | PCI29732, PCI-29732 |
| Application: | Multi-kinase inhibitor |
| CAS | 330786-25-9 |
| MW: | 371.43 D |
From 34.00€
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AMG-47a
Item number: TGM-T7123-100mg
Description: AMG-47a is a potent inhibitor of Lck and T cell proliferation. AMG-47a could promote the degradation of the KRAS oncoprotein. AMG-47a selectively reduced the levels of EGFP-KRASG12V protein but did not affect EGFP protein in cells. Target: JAK, VEGFR, p38 MAPK, Src. Smiles:...
| Application: | Lck/VEGFR2/p38alpha/JAK3 inhibitor |
| CAS | 882663-88-9 |
| MW: | 535.56 D |
From 40.00€
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Lck inhibitor II
Item number: TGM-T68349-100mg
Description: Lck inhibitor II is a cell-permeable, ATP binding site-targeting, tri-substituted pyrimidine that acts as a highly potent Lck (lymphocyte specific kinase) inhibitor. Target: Others. Smiles: N(C1=NC(N2C=3C(N=C2)=CC=CC3)=NC(OCCN4CCOCC4)=C1)C5=C(C)C=CC(O)=C5
| Application: | Lck inhibitor |
| CAS | 918870-43-6 |
| MW: | 446.5 D |
From 1,520.00€
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Lck Inhibitor III
Item number: TGM-T72586-100mg
Description: Lck Inhibitor III, a potent inhibitor of Lck, exhibits an IC50 value of 867 nM. Additionally, this compound effectively inhibits IL-2 synthesis in Jurkat cells, demonstrating an IC50 of 1.270 µM. Target: Others. Smiles: O.N1=CN(C2=NC(OCCN3CCOCC3)=CC(=N2)NC4=CC(OC)=CC=C4C)C=5C=CC=CC15
| Application: | Lck inhibitor |
| CAS | 1188890-30-3 |
| MW: | 478.54 D |
From 1,520.00€
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Anti-LCK
Item number: CSB-PA003142.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Keywords: | Anti-LSK, Anti-LCK, Anti-p56-LCK, EC=2.7.10.2, Anti-Protein YT16, Anti-Proto-oncogene Lck, Anti-Tyrosine-protein kinase... |
| Application: | ELISA, WB |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 126.00€
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