- Search results for K05696
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53 products were found matching "K05696"!
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Item number: Cay40169-5
ABBV-CLS-484 is a dual inhibitor of protein tyrosine phosphatase non-receptor type 1 (PTPN1) and PTPN2 (IC50s = 2.5 and 1.8 nM, respectively). It is selective for PTPN1 and PTPN2 over PTP6N and PTP11N (IC50s = >10 µM for both) but does inhibit PTP9N (IC50 = 15 nM). ABBV-CLS-484 (1 µM) potentiates IFN-gamma-induced...
Keywords: | Osunprotafib,... |
Application: | Dual PTPN1/PTPN2 inhibitor |
MW: | 385.5 D |
From 669.00€
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-10 %
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Item number: ELK-ELK4485.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PTPN1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PTPN1. Next,...
Keywords: | PTP1B, PTPN1, PTP-1B, EC=3.1.3.48, Protein-tyrosine phosphatase 1B, Tyrosine-protein phosphatase non-receptor type 1 |
Application: | ELISA |
Species reactivity: | human |
365.00€
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From 328.50€
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-10 %
Item number: AG-CN2-0488-M001
Yellow solid. Soluble in DMSO, ethanol or methanol. Mycotoxin. Common contaminant in corn and other grains. Hybrid dimer of Blennolide A and B, Cytotoxic anticancer compound. Reported to induce apoptosis by modulating RhoGDI 2 levels in HL60 cells, Protein tyrosine phosphatase 1B (PTP1B) inhibitor (IC50=9.6&mu,M)....
Keywords: | SAF, Ergochrome BE |
Application: | Mycotoxin, PTP1B inhibitor |
CAS | 60687-07-2 |
MW: | 638,6 D |
105.00€
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94.50€
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Item number: Cay10010896-100
Protein tyrosine phosphatase (PTPs) are an enzyme superfamily that includes about 100 human proteins. Their function is to remove phosphate from tyrosine residues of cellular proteins. Reversible phosphorylation catalyzed by the coordinated actions of protein tyrosine kinases and phosphatases is of paramount...
Keywords: | PTPN1, PTP1B, PTP-1B, PTP-1B, Protein-tyrosine phosphatase 1B, Protein-tyrosine phosphatase 1B, Tyrosine-protein... |
Application: | Enzyme activity |
MW: | 37,3 kD |
369.00€
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Item number: BPS-30009
Active protein tyrosine phosphatase, full length, (a.a. 1-436), (Gene bank accession number M31724) with N terminal GST tag, MW=76 kDa, expressed in an E. coli expression system.
Keywords: | PTP1B, PTPN1, PTP-1B, EC=3.1.3.48, Protein-tyrosine phosphatase 1B, Tyrosine-protein phosphatase non-receptor type 1, |
Application: | Enzyme kinetics, dephosphorylation, inhibitor screening |
MW: | 76 kD |
481.00€
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Item number: Cay11684-10
Bakuchiol is a natural meroterpene isolated from P. corylifolia, a plant used in traditional Asian medicine. In addition to having antioxidant and antibacterial actions, bakuchiol has retinol-like effects on gene expression and properties of the skin. Bakuchiol also inhibits DNA polymerase and...
Keywords: | (S)-(+)-Bakuchiol, 4-[(1E,3S)-3-ethenyl-3,7-dimethyl-1,6-octadien-1-yl]-phenol |
Application: | PTP1B inhibitor |
CAS | 10309-37-2 |
MW: | 256.4 D |
From 72.00€
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Item number: Cay15782-1
Protein tyrosine phosphatase 1B (PTP1B) has critical roles in cell signaling relevant to diabetes, obesity, and cancer. PTP1B inhibitor is a cell-permeable allosteric inhibitor of PTP1B (IC50s = 4 and 8 µM for 403 and 298 residue PTP1B forms, respectively). It binds reversibly and non-competitively, altering the...
Keywords: | Protein Tyrosine Phosphatase 1B Inhibitor,... |
Application: | Cell-permeable allosteric PTP1B inhibitor |
CAS | 765317-72-4 |
MW: | 741.5 D |
From 82.00€
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Item number: BPS-79764
Protein phosphorylation is one of the most important post-translational modification processes. Phosphorylation is reversibly regulated by Protein Kinases (PKs) and Protein Phosphatases (PTPs). PTP1B (PTPN1) is known to catalyze dephosphorylation of insulin receptor kinases and plays a critical role in insulin...
Keywords: | PTPN1, Protein tyrosine phosphatase 1B, ptp, |
Application: | Enzyme kinetics, HTS |
Species reactivity: | human |
628.00€
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Item number: BPS-30010
Active protein tyrosine phosphatase, recombinant from E.coli, catalytic domain, (a.a. 1-321), (Gene bank accession no. M31724) with N-terminal GST tag, MW=63.3 kDa, expressed in an E. coli expression system.
Keywords: | PTP1B, PTPN1, PTP-1B, EC=3.1.3.48, Protein-tyrosine phosphatase 1B, Tyrosine-protein phosphatase non-receptor type 1, |
Application: | Enzyme kinetics, dephosphorylation, inhibitor screening |
MW: | 63.3 kD |
481.00€
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Item number: Cay19450-500
Protein tyrosine phosphatases (PTPs) remove phosphate from tyrosine residues of cellular proteins. Reversible phosphorylation catalyzed by the coordinated actions of protein tyrosine kinases and phosphatases is key to the regulation of the signaling events that control cell growth and proliferation, differentiation,...
Keywords: | CI-010, TAN 1364B, (5R)-4-hydroxy-5-(hydroxymethyl)-3-(1-oxohexadecyl)-2(5H)-furanone, calcium salt (2:1) |
Application: | Protein tyrosine phosphatase inhibitor |
CAS | 332131-32-5 |
MW: | 775.1 D |
From 324.00€
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Item number: Cay18458-10
Protein tyrosine phosphatases (PTPs) remove phosphate from tyrosine residues of cellular proteins. Reversible phosphorylation catalyzed by the coordinated actions of protein tyrosine kinases and phosphatases is key to the regulation of the signaling events that control cell growth and proliferation, differentiation,...
Keywords: | Protein Tyrosine Phosphatase Inhibitor IV,... |
Application: | SHP-2, PTP1B, PTP-epsilon, PTP-Meg-2, PTP-sigma, PTP-beta, PTP-µ inhibitor |
CAS | 329317-98-8 |
MW: | 608.6 D |
From 43.00€
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Item number: A302-297A
Protein function: Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK, inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May...
Keywords: | Anti-PTPN1, Anti-PTP1B, Anti-PTP-1B, EC=3.1.3.48, Anti-Protein-tyrosine phosphatase 1B, Anti-Tyrosine-protein phosphatase... |
Application: | WB, IP |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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