146 products were found matching "K05638"!

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human NFE2L2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human NFE2L2....

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat NFE2L2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat NFE2L2. Next,...

Nuclear factor E2-related factor 2 (Nrf2) is a transcription factor that plays a key role in maintaining redox homeostasis via its interaction with a cysteine-rich protein Kelch-like ECH-associated protein 1 (Keap1). In resting cells, Nrf2 and Keap1 form a tight complex, which is targeted for degradation by...

L-Sulforaphane is an isothiocyanate derived from the natural compound glucoraphanin, which is abundant in cruciferous vegetables, including broccoli. It has powerful antioxidant, anti-inflammatory, and anti-carcinogenic effects. L-Sulforaphane, at 40 µM, activates nuclear factor erythroid 2-related factor 2- (Nrf2)...

Description: Rebaudioside A (Reb A) is a novel agent of glycoside clathration of pharmacons, acts as alpha-glucosidase inhibitor. Target: Glucosidase, Endogenous Metabolite. Smiles:...

Description: NFE2L2 Protein, Human, Recombinant (aa 1-605, His) is expressed in E. coli. The accession number is Q16236.

4-octyl Itaconate is a prodrug form of itaconate, an endogenous cellular metabolite produced via decarboxylation of cis-aconitate by the enzyme encoded by IRG1. It is hydrolyzed to itaconate by esterases in C2C12 cells and LPS-activated mouse macrophages where it acts as a regulator of macrophage function with...

Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. NRF2 antibody detects Nuclear factor erythroid 2-related factor 2, a transcription factor that regulates antioxidant defense and cellular detoxification. The UniProt recommended name is Nuclear factor erythroid 2-related factor 2 (NFE2L2)....

Glucoraphanin is a natural glycoinsolate found in cruciferous vegetables, including broccoli. It is converted to the isothiocyanate sulforaphane by the enzyme myrosinase. Sulforaphane has powerful antioxidant, anti-inflammatory, and anti-carcinogenic effects. It acts by activating nuclear factor erythroid 2-related...

[D-Asp3]-Microcystin-LR is a cyanotoxin that has been found in Anabaena and an activator of nuclear factor erythroid 2-related factor 2 (Nrf2). It induces Nrf2 activation in HepG2 cells when used at concentrations ranging from 0.3-3 µM. InChI:...

A chiral natural product from broccoli. Also an inducer of phase II enzymes.

The synthetic oleanane triterpenoid CDDO (Cay-81035) is a Nrf2 activator that inhibits proliferation and induces differentiation and apoptosis in various cancer cells. The C-28 methyl ester of CDDO (CDDO methyl ester) blocks the cellular synthesis of inducible nitric oxide synthase (iNOS) and inducible COX-2 in...