- Search results for K05625
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128 products were found matching "K05625"!
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Item number: Cay42340-10
TG2-IN-1 is an irreversible inhibitor of transglutaminase 2 (TG2). It inhibits guinea pig liver TG2 (IC50 = 4 µM) and inhibits recombinant human Factor XIIIa in a concentration-dependent manner. TG2-IN-1 (20-500 µM) reduces gamma-glutamyl-epsilon-lysine isopeptide levels, a marker of TG2 activity, in SH-SY5Y cells...
| Keywords: | D003, NTU283, R283, TG2 Inhibitor 1, Transglutaminase 2 Inhibitor 1, Transglutaminase 2-IN-21,... |
| Application: | Irreversible transglutaminase 2 (TG2) inhibitor |
| CAS | 135273-74-4 |
| MW: | 220.72 D |
From 107.00€
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Item number: GSC-Z05875-100
Transglutaminase 2 (TGM2) is a member of the transglutaminase family, and it is reported to be associated with chemoresistance in various types of cancer. TGM2 was demonstrated to affect the chemosensitivity of osteosarcoma cells via regulation of the activation of mitogen-activated protein kinase and AKT...
| Keywords: | TGM2, Heart G alpha(h), Isopeptidase TGM2, Transglutaminase-2, Protein G alpha(h), Transglutaminase H, Transglutaminase C,... |
| Origin: | human |
| MW: | 78.4 kD |
From 497.00€
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Item number: GSC-Z06370-100
Transglutaminase 2 (TGM2) is a member of the transglutaminase family, and it is reported to be associated with chemoresistance in various types of cancer. TGM2 was demonstrated to affect the chemosensitivity of osteosarcoma cells via regulation of the activation of mitogen-activated protein kinase and AKT...
| Keywords: | Tgm2, Isopeptidase TGM2, Transglutaminase-2, Transglutaminase II, Tissue transglutaminase, Protein-glutamine deamidase... |
| Origin: | mouse |
| MW: | 78.2 kD |
From 497.00€
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Item number: Cay42453-10
An inhibitor of TG2 (Ki = 0.068 mM), reduces radiation-induced increases in TGM2 expression in wild-type H1299 and H1299/M175H-p53 cells at 3.91 µM, sensitizes wild-type H1299 and H1299/M175H-p53 cells to radiation and induces cell cycle arrest at the G0/G1 and G2/M phases, respectively, inhibits fibronectin...
| Keywords: | ERW1095B, N-[(1S)-2-[[(3-bromo-4,5-dihydro-5-isoxazolyl)methyl]amino]-1-[(4-hydroxyphenyl)methyl]-2-oxoethyl]-carbamic... |
| Application: | TGM2 (transglutaminase 2) inhibitor |
| CAS | 744198-19-4 |
| MW: | 476.32 D |
From 349.00€
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Item number: G-HUFI00334.96
| Application: | ELISA |
| Species reactivity: | human |
698.00€
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Item number: Cay42514-10
TG53 is an inhibitor of the protein-protein interaction between transglutaminase 2 (TG2) and fibronectin (IC50 = 10 µM in a cell-free assay). It inhibits the adhesion of SKOV3 ovarian cancer cells to fibronectin-coated wells when used at a concentration of 25 µM. TG53 (10 µM) inhibits migration and invasion in a...
| Keywords: | 5-chloro-N-[4-[[4-(dimethylamino)-6-methyl-2-pyrimidinyl]amino]phenyl]-2-methoxy-benzamide |
| Application: | TG2-fibronectin protein-protein interaction inhibitor |
| CAS | 946369-04-6 |
| MW: | 411.88 D |
From 103.00€
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Item number: A304-229A
Protein function: Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. [The UniProt Consortium]
| Keywords: | Anti-TGC, Anti-TGM2, Anti-TG(C), Anti-TGase C, Anti-TGase-2, Anti-TGase H, EC=2.3.2.13, Anti-Transglutaminase C,... |
| Application: | WB, IP |
| Host: | Rabbit |
| Species reactivity: | human |
From 165.00€
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Item number: NSJ-R32370
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Transglutaminase 2, also called TGC, TG2 and TGM2, is a 78-kDa, calcium dependent enzyme of the protein-glutamine gamma-glutamyltransferases family. Transglutaminases (TGs) are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine...
| Keywords: | Anti-TGC, Anti-TGM2, Anti-TG(C), Anti-TGase C, Anti-TGase-2, Anti-TGase H, EC=2.3.2.13, Anti-Transglutaminase C,... |
| Application: | WB, IHC (paraffin), IF |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
790.00€
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Item number: Cay14882-25
Tissue transglutaminase (TGM2) post-translationally modifies proteins by catalyzing intermolecular cross-linkages between glutamine and lysine side chains. TGM2 has roles in neurodegenerative disorders, celiac sprue, cancer, and fibrotic diseases. Cystamine is an organic disulfide that inhibits TGM2 with an IC50...
| Keywords: | 2,2'-dithiobis-ethanamine, dihydrochloride |
| Application: | TGM2 inhibitor |
| CAS | 56-17-7 |
| MW: | 225.2 D |
From 38.00€
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Item number: ARG10593.50
Protein function: Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. [The UniProt Consortium]
| Keywords: | Anti-TGC, Anti-TGM2, Anti-TG(C), Anti-TGase-2, Anti-TGase C, Anti-TGase H, EC=2.3.2.13, Anti-Transglutaminase-2,... |
| Application: | WB, IHC (paraffin), IHC (frozen) |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
551.00€
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Item number: ARG56251.100
Protein function: Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. [The UniProt Consortium]
| Keywords: | Anti-TGC, Anti-TGM2, Anti-TG(C), Anti-TGase-2, Anti-TGase H, Anti-TGase C, EC=2.3.2.13, Anti-Transglutaminase H,... |
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | human |
707.00€
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Item number: ARG64233.100
Protein function: Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. [The UniProt Consortium]
| Keywords: | Anti-TGC, Anti-TGM2, Anti-TG(C), Anti-TGase H, Anti-TGase-2, Anti-TGase C, EC=2.3.2.13, Anti-Transglutaminase C,... |
| Application: | ELISA, WB |
| Host: | Goat |
| Species reactivity: | human |
871.00€
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