18 products were found matching "K05607"!

Tag: C-His. Modification: unmodified. Start Site: Met71. End Site: Ser150. Coverage: 0.31. Isoelectric Point: 10. Core Sequence: MKTEDELRVR HLEEENRGIV VLGINRAYGK NSLSKNLIKM LSKAVDALKS DKKVRTIIIR SEVPGIFCAG ADLKERAKMS. Homologies: Highest protein sequence identity to the following orthologs: Mouse - 95%, Rat - 97%,...

Tag: C-His. Modification: unmodified. Start Site: Met71. End Site: Ser150. Coverage: 0.31. Isoelectric Point: 10. Core Sequence: MKTEDELRVR HLEEENRGIV VLGINRAYGK NSLSKNLIKM LSKAVDALKS DKKVRTIIIR SEVPGIFCAG ADLKERAKMS. Homologies: Highest protein sequence identity to the following orthologs: Mouse - 95%, Rat - 97%,...

3-Methylglutaconic acid (3-MGA) is a branched-chain organic acid and product of leucine catabolism. 3-MGA accumulates in 3-methylglutaconic aciduria, which is caused by an inborn error of leucine metabolism characterized by 3-MGA-CoA hydratase deficiency, leading to delayed development, hypoglycemia, metabolic...

Recombinant human CDK2 and CyclinA2, full length, with N-terminal GST-tags, were co-expressed in Sf9 insect cells via a baculovirus expression system.

Protein function: Catalyzes the conversion of 3-methylglutaconyl-CoA to 3- hydroxy-3-methylglutaryl-CoA (PubMed:11738050, PubMed:12434311, PubMed:12655555). Also has itaconyl-CoA hydratase activity by converting itaconyl-CoA into citramalyl-CoA in the C5- dicarboxylate catabolism pathway (PubMed:29056341). The C5-...

3-Methylglutaric acid is a metabolite of the essential amino acid L-leucine (Cay-34342). It is produced by hydrolysis of the L-leucine catabolic intermediate 3-methylglutaconyl-CoA (3-MG-CoA), which accumulates when the activity of 3-MG-CoA hydratase, the enzyme that converts 3-MG-CoA to HMG-CoA, is deficient, in...

Protein function: Catalyzes the conversion of 3-methylglutaconyl-CoA to 3- hydroxy-3-methylglutaryl-CoA (PubMed:11738050, PubMed:12434311, PubMed:12655555). Also has itaconyl-CoA hydratase activity by converting itaconyl-CoA into citramalyl-CoA in the C5-dicarboxylate catabolism pathway (PubMed:29056341). The...

Rabbit Polyclonal AUH Antibody against Human AU RNA binding methylglutaconyl-CoA hydratase. Validated for Western Blot. Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Interspecies information: Highest antigen sequence indentity to the following orthologs: ENSMUSG00000021460: 99%,...

Description: Methylglutaric acid is a leucine metabolite. A large amount of methylglutaric acid is identified in urine of patients with deficiency of 3-methylglutaconyl coenzyme A hydratase (PMID 6181239 ). Methylglutaric acid is also found to be associated with 3-hydroxy-3-methylglutaryl-CoA lyase deficiency,...

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....

AuH, also known as mitochondrial methylglutaconyl-CoA hydratase, is involved in the aa degradation pathway by catalyzing the conversion of 3-methylglutaconyl-CoA to 3-hydroxy-3- methylglutaryl-CoA and water. It has been found to have very low enoyl-CoA hydratase activity. Source: Recombinant protein corresponding to...