- Search results for K05411
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95 products were found matching "K05411"!
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Item number: ELK-ELK2854.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse IRF3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse IRF3. Next,...
Keywords: | Irf3, IRF-3, Interferon regulatory factor 3 |
Application: | ELISA |
Species reactivity: | mouse |
From 365.00€
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Item number: ELK-ELK2074.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human IRF3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human IRF3. Next,...
Keywords: | IRF-3, Interferon regulatory factor 3 |
Application: | ELISA |
Species reactivity: | human |
From 365.00€
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Item number: Cay27886-1
STING agonist C11 is an agonist of the stimulator of interferon genes (STING) pathway. It induces secretion of type I IFN from THF and MM6 cells when used at a concentration of 50 µM. STING agonist C11 induces phosphorylation of IFN regulatory factor 3 (IRF3) and increases expression of IFIT1 and viperin, but not...
Keywords: | N-[(methylamino)carbonyl]-alpha-[[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]thio]-benzeneacetamide |
Application: | Stimulator of interferon genes (STING) pathway agonist |
CAS | 875863-22-2 |
MW: | 382.4 D |
From 83.00€
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Item number: Cay38980-1
KIN1148 is an IFN regulating factor 3 (IRF3) activator and adjuvant. It increases the mRNA expression of the genes encoding IFN-stimulated gene 54 (ISG54) and 2'-5'-oligoadenylate synthase-like (OASL) protein in PH5CH8 cells and increases chemokine (C-X-C motif) ligand 10 (CXCL10) production in phorbol 12-myristate...
Keywords: | N-benzo[1,2-d:3,4-d']bisthiazol-2-yl-2-naphthalenecarboxamide |
Application: | IRF3 activator, adjuvant |
CAS | 1428729-56-9 |
MW: | 361.4 D |
From 104.00€
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Item number: A300-426A
Protein function: Key transcriptional regulator of type I interferon (IFN)-dependent immune responses which plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an...
Keywords: | Anti-IRF3, Anti-IRF-3, Anti-Interferon regulatory factor 3 |
Application: | WB, IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: A303-384A
Protein function: Key transcriptional regulator of type I interferon (IFN)-dependent immune responses which plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an...
Keywords: | Anti-Irf3, Anti-IRF-3, Anti-Interferon regulatory factor 3 |
Application: | WB, IP |
Host: | Rabbit |
Species reactivity: | mouse |
From 164.00€
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Item number: Cay27884-10
Cridanimod is an inducer of type I interferon (IFN) production. It induces IRF3 phosphorylation, IFN-beta production, and NF-kappaB activation in wild-type, but not in stimulator of interferon genes (STING) mutant, murine macrophages. In vivo, cridanimod (112-1,792 mg/kg) increases plasma levels of IFN in weanling...
Keywords: | 10-Carboxymethyl-9-Acridanone, 9-oxo-10(9H)-acridineacetic acid, monosodium salt |
Application: | Type I interferon (IFN) production inducer, IRF3 phosphorylation inducer |
CAS | 58880-43-6 |
MW: | 275.2 D |
From 43.00€
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Item number: ARG56578.50
Protein function: Key transcriptional regulator of type I interferon (IFN)-dependent immune responses which plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an...
Keywords: | Anti-IRF3, Anti-IRF-3, Anti-Interferon regulatory factor 3 |
Application: | ICC, IF, IHC (paraffin), WB |
Host: | Rabbit |
Species reactivity: | human, mouse |
520.00€
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Item number: ARG56940.50
Protein function: Key transcriptional regulator of type I interferon (IFN)-dependent immune responses which plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an...
Keywords: | Anti-IRF3, Anti-IRF-3, Anti-Interferon regulatory factor 3 |
Application: | WB, IP |
Host: | Mouse |
Species reactivity: | human |
488.00€
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Item number: ARG57516.50
Protein function: Key transcriptional regulator of type I interferon (IFN)-dependent immune responses which plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an...
Keywords: | Anti-phospho-IRF3, Anti-phospho-IRF-3, Anti-phospho-Interferon regulatory factor 3 |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human |
488.00€
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Item number: Cay21790-10
KIN1408 is a small molecule activator of the RIG-1-like receptor (RLR) pathway that has antiviral activity. It induces interferon regulatory factor 3 (IRF3) activation and translocation into the nucleus in a concentration-dependent manner in HEK293 cells without inducing cellular toxicity. KIN1408 induces expression...
Keywords: | 7-[[4-(difluoromethoxy)phenyl][(5-methoxy-2-benzothiazolyl)amino]methyl]-8-quinolinol |
Application: | IRF3 activator |
CAS | 1903800-11-2 |
MW: | 479.5 D |
From 125.00€
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Item number: Cay22811-100
Interferon regulatory factor 3 (IRF3) is a member of the IRF family. It plays a crucial role in activation of innate immunity and inflammation in response to viral infection, functioning as a molecular switch for antiviral activity. Double-stranded RNA generated during a viral infection leads to IRF3 activation by...
Keywords: | IRF-3 {ECO:0000303|PubMed:9566918}, IRF-3 {ECO:0000303|PubMed:9566918}, Interferon regulatory factor 3... |
Application: | Cell based assays, electrophoresis, IP, MS, WB |
649.00€
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