49 products were found matching "K05410"!

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human TBK1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human TBK1. Next,...

Soluble in DMSO or dimethylformamide. Antiallergic. Anti-inflammatory. Antagonizes the angiogenic and mitogenic activity of FGF-1 through S100A13. Inhibits FGF-1 release. Binds to HSP90. Inhibits C-terminal chaperone activity. Induces an increase in nonsense-containing mRNAs amount in treated cells, leading to...

MRT67307 is a kinase inhibitor that has been shown to inhibit TBK1, MARK1-4, IKKepsilon, and NUAK1 (IC50 values are 19, 27-52, 160, and 230 nM, respectively), the salt-inducible kinases (SIKs, IC50s = 250, 67, and 430 nM for SIK1, SIK2, and SIK3, respectively) and ULK1 and ULK2 (IC50s = 45 and 38 nM, respectively)....

Recombinant human TBK1, full length, with N-terminal GST-tag, expressed in Sf9 insect cells via a baculovirus expression system.

Protein function: Serine/threonine kinase that plays an essential role in regulating inflammatory responses to foreign agents. Following activation of toll-like receptors by viral or bacterial components, associates with TRAF3 and TANK and phosphorylates interferon regulatory factors (IRFs) IRF3 and IRF7 as well as...

Protein function: Serine/threonine kinase that plays an essential role in regulating inflammatory responses to foreign agents. Following activation of toll-like receptors by viral or bacterial components, associates with TRAF3 and TANK and phosphorylates interferon regulatory factors (IRFs) IRF3 and IRF7 as well as...

TANK-binding kinase 1 (TBK1) is a non-canonical inhibitor of NF-kappaB kinase (IKK) that has an essential role in regulating inflammatory responses to pathogens. Following activation of toll-like receptors by viral DNA, TBK1 interacts with various partners such as STING, MAVS, and TANK to phosphorylate and activate...

Anti-TBK1 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Anti-TBK1 from Human, Mouse, cow,dog and rat based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-TBK1 from other sources has not been determined. Protein function:...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Serine/threonine-protein kinase TANK-binding kinase 1 or NF-kappa-B-activating kinase is an enzyme that in humans is encoded by the TBK1 gene. The gene was assigned to human chromosome 12q14.2. Serine/threonine kinases plays an essential role in regulating...

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: TANK-binding kinase 1, NAK, NF-kB-activating kinase Protein function: Serine/threonine kinase that plays an essential role in regulating inflammatory responses to foreign agents. Following...

In 1X PBS, pH 7.4, with 0.09% sodium azide. Serine/threonine protein involved in the signaling cascade converging to the activation of the transcription factor NF-kappa-B. May function as an IKK kinase, playing an essential role in the transcription of a subset of a TNF-alpha-induced genes. Also mediates production...