24 products were found matching "K05218"!

BAY-1797 is an antagonist of the purinergic P2X4 receptor (IC50 = 0.211 µM for the human receptor). It is selective for P2X4 over P2X1, P2X3, and P2X7 receptors (IC50s = >50, 8.3, and 10.6 µM, respectively, for the human receptors), as well as a panel of G protein-coupled receptors (GPCRs), ion channels, kinases,...

Protein function: Receptor for ATP that acts as a ligand-gated ion channel. This receptor is insensitive to the antagonists PPADS and suramin. [The UniProt Consortium]

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Purinoceptor P2X4, also called P2X4R is a protein that in humans is encoded by the P2RX4 gene. This gene belongs to the family of purinoceptors for ATP. P2RX4 is a receptor for ATP that acts as a ligand-gated ion channel. P2X4 in hyperactive microglia is...

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Purinergic receptor P2X, ligand-gated ion channel, 4 Protein function: Receptor for ATP that acts as a ligand-gated ion channel. This receptor is insensitive to the antagonists PPADS and...

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: P2X purinoceptor 4 Protein function: Receptor for ATP that acts as a ligand-gated ion channel. This receptor is insensitive to the antagonists PPADS and suramin. [The UniProt Consortium]

BX-430 is a noncompetitive allosteric antagonist of the purinergic P2X4 receptor (IC50s = 0.54 and 1.89 µM for the human and Xenopus receptors, respectively). BX-430 is selective for the human P2X4 receptor over the human P2X1, P2X2, P2X5, P2X3, and P2X7 receptors at 5 µM and over mouse and rat P2X4 receptors at 10...

Protein function: Receptor for ATP that acts as a ligand-gated ion channel. This receptor is insensitive to the antagonists PPADS and suramin. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 83% and to rat: 77%

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human P2RX4. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human P2RX4. Next,...

A P2X4 receptor antagonist (IC50 = 0.75 µM), selective for P2X4 over P2X1, P2X2a, P2X2b, and P2X7 but does inhibit P2X3 by 35.9% at 10 µM, decreases fEPSP slopes in rat hippocampal slices at 10 µM, inhibits nitroglycerin-induced mechanical hyperalgesia in a mouse model of chronic migraine at 28 mg/kg, decreases...

Protein function: Receptor for ATP that acts as a ligand-gated ion channel. This receptor is insensitive to the antagonists PPADS and suramin. [The UniProt Consortium]

Protein function: Receptor for ATP that acts as a ligand-gated ion channel. This receptor is insensitive to the antagonists PPADS and suramin. [The UniProt Consortium]

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....