25 products were found matching "K05215"!

Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. P2RX1 antibody detects P2X purinoceptor 1, encoded by the P2RX1 gene on chromosome 17p13.2. P2RX1 antibody is widely used in neurobiology, immunology, and cardiovascular research. P2X1 is a ligand-gated ion channel activated by extracellular...

NF449 is an analog of suramin that selectively inhibits P2X1 purinergic receptors (pIC50 = 6.3) with a potency 19-fold greater than at P2X3, P2Y1, P2Y2, or P2Y11. Through selective inhibition of the P2X1 receptor, 10 mg/kg NF449 has been used to decrease intravascular platelet aggregation in a mouse model of...

alpha,beta-Methyleneadenosine 5'-triphosphate (alphabeta-methylene ATP) is a phosphonic analog of ATP that is characterized by the replacement of the bridging oxygen atom between the alpha- and beta-phosphate groups with methylene. It is an agonist of P2X purinoceptors P2X1 and P2X3 (EC50 = ~1 µM) and is ~1,000-fold...

TNP-ATP is a derivative of ATP and an antagonist at the purinergic receptor subtypes P2X1, P2X3, and P2X2/3 (IC50s = 6, 0.9, and 7 nM, respectively). It is selective for those receptor subtypes over P2X2, P2X4, and P2X7 receptors (IC50s = 2,000, 15,200, and >30,000 nM, respectively). TNP-ATP inhibits calcium flux in...

NF 023 is a purinergic P2X1 receptor antagonist (IC50 = 0.21 µM). It is selective for P2X1 over P2X2-4 receptors (IC50s = >50, 28.9 and >100 µM, respectively). It inhibits alpha,beta-methylene ATP-induced vasoconstriction in isolated rabbit saphenous arteries (pA2 = 5.69). NF 023 also inhibits hepatitis C virus...

Description: NF023 hexasodium is a selective and competitive P2X1 receptor antagonist with IC50 values of 0.21 µM, 28.9 µM, > 50 µM, and > 100 µM for human [P2X1], [P2X3], [P2X2], and [P2X4]-mediated responses, respectively. Target: P2X Receptor. Smiles:...

Polyclonal Antibody against Human P2RX1, Gene description: purinergic receptor P2X 1, Alternative Gene Names: P2X1, Validated applications: ICC, Uniprot ID: P51575, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C. Protein function: Ligand-gated ion channel with relatively...

Polyclonal Antibody against Human P2RX1, Gene description: purinergic receptor P2X 1, Alternative Gene Names: P2X1, Validated applications: ICC, Uniprot ID: P51575, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C. Protein function: Ligand-gated ion channel with relatively...

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic...