36 products were found matching "K05211"!

D-AP5 is a selective N-methyl-D-aspartate (NMDA) receptor antagonist (Kd = 1.4 µM) that competitively inhibits the glutamate binding site of NMDA receptors. Whereas D-AP5 is the active (-)-stereoisomer, its (+)-isomer (L-AP5) demonstrates considerably less potent NMDA receptor antagonist activity. AP5 has been...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human GRIN2C. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human GRIN2C....

Protein function: NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. [The UniProt Consortium]

Anti-NMDA R2C antibody is directed against NMDA R2C protein. The antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Immunolabeling is blocked by preadsorption of antibody with the immunogen that was used to generate the antibody. Reactivity is expected from human and mouse....

Anti-NMDA R2C pS1096 antibody is directed against phophorylated NMDA 2C receptor protein.The antibody was affinity purified from monospecific antiserum by immunoaffinity purification. The antibody is specific for NMDA 2C receptor phosphorylated at S1096. Reactivity is expected from the following species based on...

Anti-NMDA R2C pS1244 antibody is directed against NMDA R2C protein. The antibody was affinity purified from monospecific antiserum by immunoaffinity purification and is specific for the phophorylated NMDA R2C protein. Immunolabeling is blocked by preadsorption of antibody with the phospho-peptide that was used to...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. NMDAR2C, known as GRIN2C, is mapped to 17q25.1. Glutamate [NMDA] receptor subunit epsilon-3 is a protein that in humans is encoded by the GRIN2C gene. NMDA receptors are found in the central nervous system, are permeable to cations and have an important role in...

1-Aminocyclopropanecarboxylic acid (ACPC) is an intermediate in the synthesis of ethylene, the plant hormone responsible for biological processes ranging from seed germination to organ senescence. ACPC has been shown to modulate NMDA receptor activity by acting as a partial agonist at the glycine-binding site on...

Flupirtine is an activator of voltage-gated potassium channel 7 (Kv7/KCNQ). It induces relaxation of preconstricted pulmonary arteries isolated from wild-type and serotonin transporter-overexpressing (SERT+) mice. Flupirtine (30 mg/kg per day) decreases mean right ventricular pressure and right ventricular...

QNZ 46 is an antagonist of NR2C- and NR2D-subunit containing NMDA receptors (IC50s = 6 and 3 µM, respectively, for receptors expressed in Xenopus oocytes). It is selective for NR2C- and NR2D-subunit containing NMDA receptors over receptors containing NR2A and NR2B subunits as well as over the AMPA receptor GluR1...

CIQ is a substituted tetrahydroisoquinoline that acts as a subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors. It is without effect at subunits NR2A, NR2B, or glutamate receptors. CIQ enhances receptor responses two-fold (EC50 = 3 µM) by increasing channel opening frequency for glutamate or...

N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are...