- Search results for K05200
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46 products were found matching "K05200"!
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Item number: Cay39842-5
GYKI 53655 is an allosteric AMPA receptor antagonist. It inhibits AMPA- and kainite-induced inward currents in whole-cell patch-clamp assays using primary rat hippocampal neurons (IC50s = 1.1 and 1.5 µM, respectively). GYKI 53655 decreases tonic and clonic audiogenic seizure severity in mice (ED50s = 1.3 and 2...
Keywords: | LY300168, 5-(4-aminophenyl)-8,9-dihydro-N,8-dimethyl-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine-7-carboxamide,... |
Application: | Allosteric AMPA receptor antagonist |
CAS | 143692-48-2 |
MW: | 388.9 D |
From 54.00€
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Item number: ELK-ELK4368.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human GRIA4. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human GRIA4. Next,...
Keywords: | GluR4, GLUR4, GluA4, GluR-D, GluR-4, Glutamate receptor 4, AMPA-selective glutamate receptor 4, Glutamate receptor... |
Application: | ELISA |
Species reactivity: | human |
From 365.00€
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Item number: ELK-ELK6922.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse GRIA4. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse GRIA4. Next,...
Keywords: | GluR4, GluA4, Gria4, Glur4, GluR-D, GluR-4, Glutamate receptor 4, AMPA-selective glutamate receptor 4, Glutamate receptor... |
Application: | ELISA |
Species reactivity: | mouse |
From 365.00€
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Item number: ELK-EA175.50
Glutamate is the major excitatory neurotransmitter and modulates its effects via ionotropic and metabotropic receptors which are different in their molecular, biochemical, pharmacological and physiological properties. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the...
Keywords: | Anti-GluA4, Anti-GluR4, Anti-GLUR4, Anti-GluR-4, Anti-GluR-D, Anti-Glutamate receptor 4, Anti-AMPA-selective glutamate... |
Application: | WB, IHC |
Host: | Rabbit |
Species reactivity: | human |
169.00€
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Item number: Cay38281-10
NBQX is an antagonist of AMPA and kainate receptors (IC50s = 0.15 and 4.8 µM, respectively). It is selective for these receptors over NMDA receptors (IC50 = >90 µM). In vivo, NBQX (20 mg/kg) increases the latency to seizures, decreases the duration of seizures, and reduces seizure severity in a rat model of epilepsy...
Keywords: | FG-9202, 1,2,3,4-tetrahydro-6-nitro-2,3-dioxo-benzo[f]quinoxaline-7-sulfonamide |
Application: | AMPA / kainate receptor antagonist |
CAS | 118876-58-7 |
MW: | 336.3 D |
From 82.00€
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Item number: ARG64711.100
Protein function: Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory...
Keywords: | Anti-GluA4, Anti-GRIA4, Anti-GluR4, Anti-GLUR4, Anti-GluR-D, Anti-GluR-4, Anti-Glutamate receptor 4, Anti-AMPA-selective... |
Application: | ELISA, IHC (paraffin), WB |
Host: | Goat |
Species reactivity: | human |
784.00€
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Item number: NSJ-R31620
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Glutamate receptor 4 also named GRIA4 or GLUR4, is a protein that in humans is encoded by the GRIA4 gene. It is mapped to 11q22.3. This gene is a member of a family of L-glutamate-gated ion channels that mediate fast synaptic excitatory neurotransmission. These...
Keywords: | Anti-GRIA4, Anti-GLUR4, Anti-GluA4, Anti-GluR4, Anti-GluR-D, Anti-GluR-4, Anti-Glutamate receptor 4, Anti-AMPA-selective... |
Application: | WB, FC |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
755.00€
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Item number: NSJ-R34495-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Glutamate receptor, ionotrophic, AMPA 4, GLUR4, GLURD Protein function: Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important...
Keywords: | Anti-GRIA4, Anti-GLUR4, Anti-GluA4, Anti-GluR4, Anti-GluR-D, Anti-GluR-4, Anti-Glutamate receptor 4, Anti-AMPA-selective... |
Application: | WB, IHC, ELISA (peptide) |
Host: | Goat |
Species reactivity: | human |
755.00€
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Item number: Cay17561-500
Tianeptine is an atypical antidepressant. It is an agonist of the µ-opioid receptor (MOR, EC50s = 194 and 641 nM for human and mouse receptors, respectively, in a BRET assay for G protein activation) and also has effects on the glutamate system. Tianeptine (30 mg/kg) decreases immobility in the forced swim test in...
Keywords: | 7-[(3-chloro-6,11-dihydro-6-methyl-5,5-dioxidodibenzo[c,f][1,2]thiazepin-11-yl)amino]-heptanoic acid, monosodium salt |
Application: | Glutamate receptor / AMPA receptor modulator |
CAS | 30123-17-2 |
MW: | 458.9 D |
From 43.00€
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Item number: Cay14937-5
S18986 is a positive allosteric modulator of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors that potently enhances (S)-AMPA-mediated noradrenaline release in rat hippocampal and frontal cortex slices. S18986 is orally bioavailable and penetrates the blood-brain barrier in animals....
Keywords: | 2,3,3aS,4-tetrahydro-1H-pyrrolo[2,1-c][1,2,4]benzothiadiazine, 5,5-dioxide |
Application: | Glutamate ionotropic receptor positive allosteric modulator |
CAS | 175340-20-2 |
MW: | 224.3 D |
From 43.00€
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Item number: Cay16335-50
Receptors for AMPA are ionotropic glutamate receptors with critical roles in neurological development and function. Cyclothiazide is a benzothiadiazide that acts as a potentiator of AMPA receptors, positively modulating its response to glutamic acid (EC50 = 3.8 µM). It blocks the rapid agonist-induced...
Keywords: | Doburil, 1,1-dioxide 3-bicyclo[2.2.1]hept-5-en-2-yl-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide |
Application: | AMPA receptor potentiator |
CAS | 2259-96-3 |
MW: | 389.9 D |
From 60.00€
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Item number: Cay14936-50
CX-516 is an AMPA receptor modulator. It increases the mean open time of AMPA receptors which increases the amplitude of trisynaptic responses to presynaptic stimulation in rat hippocampal slices. In vivo, CX-516 (10-50 mg/kg) accelerates acquisition of a conditioned fear response in rats in a dose-dependent manner....
Keywords: | Ampalex, BDP-12, Benzoyl-Piperidine-12, 1-piperidinyl-6-quinoxalinyl-methanone |
Application: | AMPA modulator |
CAS | 154235-83-3 |
MW: | 241.3 D |
From 68.00€
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