- Search results for K05199
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41 products were found matching "K05199"!
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Item number: Cay39842-25
GYKI 53655 is an allosteric AMPA receptor antagonist. It inhibits AMPA- and kainite-induced inward currents in whole-cell patch-clamp assays using primary rat hippocampal neurons (IC50s = 1.1 and 1.5 µM, respectively). GYKI 53655 decreases tonic and clonic audiogenic seizure severity in mice (ED50s = 1.3 and 2...
Keywords: | LY300168, 5-(4-aminophenyl)-8,9-dihydro-N,8-dimethyl-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine-7-carboxamide,... |
Application: | Allosteric AMPA receptor antagonist |
CAS | 143692-48-2 |
MW: | 388.9 D |
From 54.00€
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Item number: ELK-ELK3969.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human GRIA3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human GRIA3. Next,...
Keywords: | GluA3, GLUR3, GRIA3, GluR-C, GluR-3, GluR-K3, Glutamate receptor 3, AMPA-selective glutamate receptor 3, Glutamate... |
Application: | ELISA |
Species reactivity: | human |
From 365.00€
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Item number: ELK-ELK6921.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse GRIA3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse GRIA3. Next,...
Keywords: | GluA3, Gria3, Glur3, GluR-C, GluR-3, GluR-K3, Glutamate receptor 3, AMPA-selective glutamate receptor 3, Glutamate... |
Application: | ELISA |
Species reactivity: | mouse |
From 365.00€
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Item number: Cay17561-50
Tianeptine is an atypical antidepressant. It is an agonist of the µ-opioid receptor (MOR, EC50s = 194 and 641 nM for human and mouse receptors, respectively, in a BRET assay for G protein activation) and also has effects on the glutamate system. Tianeptine (30 mg/kg) decreases immobility in the forced swim test in...
Keywords: | 7-[(3-chloro-6,11-dihydro-6-methyl-5,5-dioxidodibenzo[c,f][1,2]thiazepin-11-yl)amino]-heptanoic acid, monosodium salt |
Application: | Glutamate receptor / AMPA receptor modulator |
CAS | 30123-17-2 |
MW: | 458.9 D |
From 43.00€
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Item number: Cay16335-25
Receptors for AMPA are ionotropic glutamate receptors with critical roles in neurological development and function. Cyclothiazide is a benzothiadiazide that acts as a potentiator of AMPA receptors, positively modulating its response to glutamic acid (EC50 = 3.8 µM). It blocks the rapid agonist-induced...
Keywords: | Doburil, 1,1-dioxide 3-bicyclo[2.2.1]hept-5-en-2-yl-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide |
Application: | AMPA receptor potentiator |
CAS | 2259-96-3 |
MW: | 389.9 D |
From 60.00€
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Item number: NSJ-R31373
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Glutamate receptor 3 is a protein that in humans is encoded by the GRIA3 gene. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. It is mapped to Xq25. Glutamate receptors are the predominant excitatory...
Keywords: | Anti-GLUR3, Anti-GRIA3, Anti-GluA3, Anti-GluR-3, Anti-GluR-C, Anti-GluR-K3, Anti-Glutamate receptor 3, Anti-AMPA-selective... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
755.00€
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Item number: NSJ-R31619
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Glutamate receptor 3 is a protein that in humans is encoded by the GRIA3 gene. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate(AMPA) receptors. It is mapped to Xq25. Glutamate receptors are the predominant excitatory...
Keywords: | Anti-GluA3, Anti-GRIA3, Anti-GLUR3, Anti-GluR-3, Anti-GluR-C, Anti-GluR-K3, Anti-Glutamate receptor 3, Anti-AMPA-selective... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
755.00€
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Item number: Cay21510-5
Farampator is a positive allosteric modulator of AMPA receptors that has an EC50 value greater than 32 µM for evoking glutamate currents in isolated pyramidal neurons. In rats, it enhances novel object recognition memory (0.1 mg/kg, p.o.) and attentional set-shifting (0.3 mg/kg, p.o.) and reverses a...
Keywords: | CX-691, 2,1,3-benzoxadiazol-5-yl-1-piperidinyl-methanone |
Application: | AMPA receptor enhancer |
CAS | 211735-76-1 |
MW: | 231.3 D |
From 54.00€
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Item number: E-AB-15811.120
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of...
Keywords: | Anti-GLUR3, Anti-GluA3, Anti-GRIA3, Anti-GluR-3, Anti-GluR-C, Anti-GluR-K3, Anti-Glutamate receptor 3, Anti-AMPA-selective... |
Application: | IHC, ELISA |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 71.00€
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Item number: Cay14937-25
S18986 is a positive allosteric modulator of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors that potently enhances (S)-AMPA-mediated noradrenaline release in rat hippocampal and frontal cortex slices. S18986 is orally bioavailable and penetrates the blood-brain barrier in animals....
Keywords: | 2,3,3aS,4-tetrahydro-1H-pyrrolo[2,1-c][1,2,4]benzothiadiazine, 5,5-dioxide |
Application: | Glutamate ionotropic receptor positive allosteric modulator |
CAS | 175340-20-2 |
MW: | 224.3 D |
From 43.00€
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Item number: Cay14936-5
CX-516 is an AMPA receptor modulator. It increases the mean open time of AMPA receptors which increases the amplitude of trisynaptic responses to presynaptic stimulation in rat hippocampal slices. In vivo, CX-516 (10-50 mg/kg) accelerates acquisition of a conditioned fear response in rats in a dose-dependent manner....
Keywords: | Ampalex, BDP-12, Benzoyl-Piperidine-12, 1-piperidinyl-6-quinoxalinyl-methanone |
Application: | AMPA modulator |
CAS | 154235-83-3 |
MW: | 241.3 D |
From 68.00€
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Item number: Cay15341-50
Talampanel is an allosteric AMPA receptor antagonist (IC50 = 2.5 µM in cerebellar Purkinje neurons using voltage-clamp electrophysiology). It reduces the firing rate of spinal neurons in rats by 68% when administered at a dose of 10 mg/kg following AMPA administration. It is protective against seizures in mouse...
Keywords: | GYKI 53773, LY 300164, (8R)-7-acetyl-5-(4-aminophenyl)-8,9-dihydro-8-methyl-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine |
Application: | Allosteric AMPA receptor antagonist |
CAS | 161832-65-1 |
MW: | 337.4 D |
From 124.00€
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