86 products were found matching "K05113"!

Protein function: Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling...

Product Description: EPH receptor B4 (EPHB4), is a member of the receptor tyrosine kinase family that plays a pivotal role in cell communication and developmental processes. EPHB4 binds promiscuously to transmembrane ephrin-B ligands on adjacent cells, initiating contact-dependent bidirectional signaling: forward...

Product Description: EPH receptor B4 (EPHB4), is a member of the receptor tyrosine kinase family that plays a pivotal role in cell communication and developmental processes. EPHB4 binds promiscuously to transmembrane ephrin-B ligands on adjacent cells, initiating contact-dependent bidirectional signaling: forward...

Product Description: EPH receptor B4 (EPHB4), is a member of the receptor tyrosine kinase family that plays a pivotal role in cell communication and developmental processes. EPHB4 binds promiscuously to transmembrane ephrin-B ligands on adjacent cells, initiating contact-dependent bidirectional signaling: forward...

For immunohistology, flow cytometry, immunofluorescence and Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.

EPHB4 together with its cognate ligand/functional ligand EFNB2 they are involved in the regulation of cell adhesion and migration, and play a central role in heart morphogenesis, angiogenesis and blood vessel remodeling and permeability. EPHB4-mediated forward signaling controls cellular repulsion and segregation...

The EphB4 receptor tyrosine kinase (cloned from erythropoietin-producing hepatocellular carcinoma) and its ligand ephrinB2 play an important role in embryonic vessel development and vascular remodeling. Signaling from this pair is also involved in tumor angiogenesis. NVP-BHG712 is an orally bioavailable inhibitor of...

XL647 is a multi-kinase inhibitor (IC50s = 0.3, 16, 1.5, 8.7, and 1.4 nM for EGFR, ErbB2, KDR, FLT4, and EphB4, respectively). It is selective for these kinases over a panel of 10 tyrosine kinases and 55 serine/threonine kinases at 10 µM. XL647 inhibits growth of A431 cells expressing wild-type EGFR and H1975...

Protein function: Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling...

Active human EPHB4 ( GenBank Accession No. NM_004444), (a.a. 563-987) with N-terminal His tag, MW=50 kDa, expressed in a Baculovirus infected Sf9 cell expression system. One unit is defined as the amount of enzyme that will transfer 1 nmol phosphate to tyrosine substrate per minute at pH 7.4 and 30° C. Assay buffer:...

Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...