19 products were found matching "K04944"!
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CyPPA
Item number: Cay15614-50
CyPPA is a positive modulator of the small-conductance calcium-activated potassium channels KCa2.2/SK2 and KCa2.3/SK3 (EC50s = 14 and 5.6 µM, respectively). It is inactive on both KCa2.1/SK1 and the intermediate conductance calcium-activated potassium channel, KCa3.1/SK4. At KCa2.3/SK3, CyPPA increases the apparent...
| Keywords: | N-cyclohexyl-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methyl-4-pyrimidinamine |
| Application: | Small conductance calcium-activated channel SK2/SK3 modulator |
| CAS | 73029-73-9 |
| MW: | 285.4 D |
From 195.00€
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Anti-KCNN3
Item number: E-AB-18172.120
KCNN3 (Potassium Calcium-Activated Channel Subfamily N Member 3) is a Protein Coding gene. Diseases associated with KCNN3 include Spinocerebellar Ataxia 2 and Bipolar Disorder. Among its related pathways are Insulin secretion and Transmission across Chemical Synapses. GO annotations related to this gene include...
| Keywords: | Anti-K3, Anti-SK3, Anti-SKCa3, Anti-KCNN3, Anti-KCa2.3, Anti-SKCa 3, Anti-Small conductance calcium-activated potassium... |
| Application: | IHC, ELISA |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 89.00€
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Anti-KCNN3
Item number: E-AB-52084.120
KCNN3 (Potassium Calcium-Activated Channel Subfamily N Member 3) is a Protein Coding gene. Diseases associated with KCNN3 include Spinocerebellar Ataxia 2 and Bipolar Disorder. Among its related pathways are Insulin secretion and Transmission across Chemical Synapses. GO annotations related to this gene include...
| Keywords: | Anti-K3, Anti-SK3, Anti-SKCa3, Anti-KCNN3, Anti-KCa2.3, Anti-SKCa 3, Anti-Small conductance calcium-activated potassium... |
| Application: | IHC, ELISA |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 89.00€
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SKA-31
Item number: Cay29690-5
SKA-31 is an activator of the small- and intermediate conductance calcium-activated potassium channels KCa2.1, KCa2.2, KCa2.3, and KCa3.1 (EC50s = 2.9, 1.9, 2.9, and 0.26 µM, respectively, in a patch-clamp assay). It also blocks the voltage-gated potassium (Kv) channels Kv1.3, Kv1.5, Kv3.1, and Kv3.2 by 10 to 30%...
| Keywords: | 2-Aminonaphthiazole, naphtho[1,2-d]thiazol-2-amine |
| Application: | KCa2/3 channel activator |
| CAS | 40172-65-4 |
| MW: | 200.3 D |
From 60.00€
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NS 13001
Item number: Cay37317-1
NS 13001 is a positive allosteric modulator for small-conductance calcium-activated potassium channel 2 (KCa2.2/SK2) and KCa2.3/SK3. It increases calcium-induced currents in an inside-out patch clamp assay using HEK293 cells expressing human KCa2.2/SK2 or KCa2.3/SK3 (EC50s = 1.8 and 0.14 µM, respectively). Oral...
| Keywords: | N-(4-chlorophenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-9-methyl-9H-purin-6-amine |
| Application: | KCa2.2/SK2 / KCa2.3/SK3 positive allosteric modulator |
| CAS | 1063331-94-1 |
| MW: | 353.8 D |
From 55.00€
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RA-2
Item number: Cay39567-10
RA-2 is an inhibitor of small-conductance calcium-activated potassium channel 2.3 (KCa2.3/SK3) and intermediate-conductance calcium-activated potassium channel 3.1 (KCa3.1/IK1) (IC50s = 2 and 17 nM, respectively). It is selective for these channels over KCa1.1/BK1, voltage-gated potassium channel 1.2 (Kv1.2), Kv1.3,...
| Keywords: | 3-fluoro-4-hydroxy-1,1'-[1,3-phenylenebis(methylene)] ester, benzoic acid |
| Application: | KCa2.3 / KCa3.1 inhibitor |
| CAS | 1867107-62-7 |
| MW: | 414.4 D |
From 153.00€
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Anti-KCNN3(SK3)
Item number: ELK-EA301.100
Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Protein function: Forms a voltage-independent potassium channel activated by intracellular calcium (PubMed:31155282, PubMed:20562108). Activation is followed by membrane...
| Keywords: | Anti-K3, Anti-SK3, Anti-KCNN3, Anti-SKCa3, Anti-KCa2.3, Anti-SKCa 3, Anti-Small conductance calcium-activated potassium... |
| Application: | IHC |
| Host: | Rabbit |
| Species reactivity: | human |
290.00€
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Anti-KCNN3
Item number: CSB-PA838540.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen....
| Keywords: | Anti-K3, Anti-SK3, Anti-SKCa3, Anti-KCNN3, Anti-SKCa 3, Anti-KCa2.3, Anti-Small conductance calcium-activated potassium... |
| Application: | ELISA, IHC |
| Host: | Rabbit |
| Species reactivity: | human, rat |
126.00€
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NS13001
Item number: TGM-T16345-100mg
Description: NS13001 (N-(4-Chlorophenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-9-methyl-9H-purin-6-amine) is a potent, selective, orally active allosteric positive modulator of SK channels (small conductance calcium-activated potassium channels). The EC50s are 1.8 and 0.14 µM for SK2 and SK3, respectively. NS13001 holds...
| Keywords: | N-(4-chlorophenyl)-2-(3,5-dimethylpyrazol-1-yl)-9-methylpurin-6-amine,... |
| Application: | KCa2.2/SK2 / KCa2.3/SK3 positive allosteric modulator |
| CAS | 1063331-94-1 |
| MW: | 353.81 D |
From 43.00€
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RA-2
Item number: TGM-T24701-10mg
Description: RA-2 is a pan-negative-gating modulator of KCa2/3 channels that acts by inhibiting EDH-type relaxation in coronary arteries. Target: Others. Smiles: C(OCC1=CC(COC(=O)C2=CC(F)=C(O)C=C2)=CC=C1)(=O)C3=CC(F)=C(O)C=C3. References: Uttley L, Bermejo I, Ren S, Martyn-St James M, Wong R, Scott DL, Young A,...
| Keywords: | RA2 |
| Application: | KCa2.3 / KCa3.1 inhibitor |
| CAS | 1867107-62-7 |
| MW: | 414.36 D |
From 187.00€
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Anti-SK
Item number: CSB-PA748713XA01DLU.100
Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
| Keywords: | Anti-dSK, Anti-CG10706, Anti-Protein SK, Anti-Small conductance calcium-activated potassium channel protein, SK Antibody |
| Application: | ELISA, WB |
| Host: | Rabbit |
| Species reactivity: | Drosophila melanogaster (Fruit fly) |
From 1,529.00€
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Anti-KCNN3 (SK3)
Item number: ELK-ES20694.100
potassium calcium-activated channel subfamily N member 3(KCNN3) Homo sapiens Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically...
| Keywords: | Anti-K3, Anti-SK3, Anti-KCNN3, Anti-SKCa3, Anti-KCa2.3, Anti-SKCa 3, Anti-Small conductance calcium-activated potassium... |
| Application: | IHC, IF |
| Host: | Rabbit |
| Species reactivity: | human, rat |
From 173.00€
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