- Search results for K04854
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13 products were found matching "K04854"!
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Item number: Cay15037-5
Mibefradil is a general calcium channel blocker that shows modest selectivity for T-type channels over L-type channels (IC50 = 2.7 and 18.6 µM, respectively). It is a potent vasodilator, increasing coronary artery flow with an EC50 value of 54 nM. Mibefradil has minimal negative inotropic effects, supporting its use...
Keywords: | Posicor, Ro 40-5967,... |
Application: | Calcium channel blocker, Vasodilator |
CAS | 116666-63-8 |
MW: | 568.6 D |
From 142.00€
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Item number: Cay26071-100
Penfluridol is a first generation typical antipsychotic that binds to dopamine receptors (IC50 = 5.6 nM). It binds to dopamine D4 receptors and also to serotonin (5-HT) receptors (Kis = 31 and 63.1 nM, respectively). Penfluridol (1.25 and 2.5 mg/kg) inhibits stereotypic behavior induced by apomorphine (Cay-16094) in...
Keywords: | R-16341, 1-[4,4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]-4-piperidinol |
Application: | Calcium channel T type blocker, Dopamine D4 receptor ligand, Serotonin (5-HT) receptor ligand |
CAS | 26864-56-2 |
MW: | 524 D |
From 50.00€
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Item number: Cay27679-5
Z944 is an inhibitor of T-type calcium channels (IC50s = 0.050-0.160 µM for the human recombinant voltage-gated calcium (Cav) channels Cav3.1, Cav3.2, and Cav3.3). It is selective for T-type channels over the N-type Cav2.2 channel (IC50 = 11 µM), as well as the rat L-type Cav1.2, human-ether-a-go-go (hERG/Kv11.1)...
Keywords: | 4-[[(3-chloro-5-fluorobenzoyl)amino]methyl]-N-(1,1-dimethylethyl)-1-piperidineacetamide |
Application: | T-type calcium channel inhibitor |
CAS | 1199236-64-0 |
MW: | 383.9 D |
From 43.00€
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Item number: Cay20385-10
Flunarizine is a calcium antagonist that acts as a potent dilator of peripheral vessels without having calcium-blocking actions in the heart. It reduces calcium fluxes in vascular smooth muscle by blocking both voltage-dependent calcium channels and receptor-operated channels. Flunarizine also acts as a dopamine D2...
Keywords: | 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenyl-2-propen-1-yl]-piperazine, dihydrochloride |
Application: | Calcium channel T type blocker |
CAS | 30484-77-6 |
MW: | 477.4 D |
From 48.00€
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Item number: Cay28374-250
Lomerizine is a voltage-dependent calcium channel blocker that inhibits low- and high-voltage activated calcium currents in rat hippocampal CA1 pyramidal neurons with IC50 values of 1.9 and 4 µM, respectively. It inhibits vasoconstriction induced by potassium chloride, serotonin (5-HT, Cay-14332), or vasopressin in...
Keywords: | KB-2796, 1-[bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]-piperazine, dihydrochloride |
Application: | Voltage-dependent calcium channel blocker |
CAS | 101477-54-7 |
MW: | 541.5 D |
From 44.00€
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Item number: G-PACO19378.50
CACNA1G Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human, Rat and for use in ELISA, IHC applications. CACNA1G Antibody is a high quality polyclonal antibody for research use only.. Protein function: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into...
Keywords: | Anti-NBR13, Anti-CACNA1G, Anti-Cav3.1c, Anti-KIAA1123, Anti-Voltage-gated calcium channel subunit alpha Cav3.1,... |
Application: | ELISA, IHC |
Host: | Rabbit |
Species reactivity: | human, rat |
363.00€
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Item number: Cay25371-10
ACT-709478 is an inhibitor of T-type voltage-gated calcium channel 3.1 (Cav3.1), Cav3.2, and Cav3.3 (IC50s = 6.4, 18, and 7.5 nM, respectively). It is selective for T-type calcium channels over the L-type calcium channel Cav1.2 (IC50 = 2,410 nM). ACT-701478 (10 mg/kg) reduces the cumulative duration of absence-like...
Keywords: | N-[1-[(5-cyano-2-pyridinyl)methyl]-1H-pyrazol-3-yl]-4-[1-(trifluoromethyl)cyclopropyl]-benzeneacetamide |
Application: | T-type calcium channels inhibitor |
CAS | 1838651-58-3 |
MW: | 425.4 D |
From 66.00€
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Item number: ELK-ES10475.100
calcium voltage-gated channel subunit alpha1 G(CACNA1G) Homo sapiens Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell...
Keywords: | Anti-NBR13, Anti-CACNA1G, Anti-Cav3.1c, Anti-KIAA1123, Anti-Voltage-gated calcium channel subunit alpha Cav3.1,... |
Application: | IHC, IF |
Host: | Rabbit |
Species reactivity: | human, rat |
From 169.00€
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Item number: VHPS-1451
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Keywords: | CACNA1G, T calcium channel alpha 1G subunit variant 153 |
Application: | RNA quantification |
43.00€
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Item number: VMPS-766
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Keywords: | Cacna1g |
Application: | RNA quantification |
43.00€
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Item number: VRPS-752
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Keywords: | Cacna1g, Voltage-gated calcium channel subunit alpha Cav3.1, Voltage-dependent T-type calcium channel subunit alpha-1G |
Application: | RNA quantification |
52.00€
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Item number: C2097-86B.100
Voltage-activated calcium channels can be distinguished based on their voltage-dependence, deactivation, and single-channel conductance. See MIM 601011. Low-voltage-activated calcium channels are referred to as 'T' type because their currents are both transient, owing to fast inactivation, and tiny, owing to small...
Keywords: | Anti-NBR13, Anti-Cav3.1c, Anti-KIAA1123, Anti-Voltage-gated calcium channel subunit alpha Cav3.1, Anti-Voltage-dependent... |
Application: | ELISA |
Host: | Goat |
Species reactivity: | human |
516.00€
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