28 products were found matching "K04824"!

0.5mg/ml if reconstituted with 0.2ml sterile DI water. The SCNN1A gene encodes the alpha subunit of the epithelial sodium channel (ENaC), a constitutively active channel that allows the flow of sodium ions from the lumen into epithelial cells across the apical cell membrane. The ENaC channel, which is regulated by...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat SCNN1a. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat SCNN1a. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human SCNN1a. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human SCNN1a....

Triamterene is an inhibitor of the epithelial sodium channel (ENaC, IC50 = 4.5 µM for the rat channel). In vivo, triamterene (0.5-32 mg/animal) enhances sodium secretion and decreases potassium secretion in adrenalectomized rats. Formulations containing triamterene have been used in the treatment of edema. This...

Amiloride is a potassium-sparing diuretic. It is an inhibitor of the epithelial sodium channel (ENaC, K0.5 = 2.6 µM for recombinant deltaENaC expressed in X. laevis oocytes). It inhibits sodium transport from bovine kidney cortex membrane vesicles with an IC50 value of 0.4 µM. Amiloride inhibits the urokinase-type...

Amiloride (hydrochloride) (Cay-26295) is an analytical reference standard categorized as a diuretic. Formulations containing diuretics, including amiloride, have been misused in sports for weight reduction and as masking agents. This product is intended for use in analytical forensic applications. This product is...

Protein function: Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells (PubMed:8382172). Plays an essential role in electrolyte and blood...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. The SCNN1A gene encodes the alpha subunit of the epithelial sodium channel (ENaC), a constitutively active channel that allows the flow of sodium ions from the lumen into epithelial cells across the apical cell membrane. The ENaC channel, which is regulated by...

Benzamil is a derivative of amiloride (Cay-14409). Benzamil is an epithelial sodium channel (ENaC) blocker that inhibits sodium transport from (IC50 = 4 nM) and binds to (Kd = 5 nM) bovine kidney cortex membrane vesicles. It is also an inhibitor of the Na+/Ca2+ exchanger (NCX) that inhibits the cytosolic calcium...

Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with...

Triamterene-d5 is intended for use as an internal standard for the quantification of triamterene (Cay-21242) by GC- or LC-MS. Triamterene is an inhibitor of the epithelial sodium channel (ENaC, IC50 = 4.5 µM for the rat channel). In vivo, triamterene (0.5-32 mg/animal) enhances sodium secretion and decreases...

Protein function: Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis,...