29 products were found matching "K04812"!

An aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anesthesia to facilitate endotraceal intubation.

Protein function: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. [The UniProt Consortium]

Rocuronium is a non-depolarizing muscle relaxant. It selectively induces neuromuscular blockade in cats (ED50s = 153, 185, 1,329, and 4,119 µg/kg for tibialis, soleus, and vagus muscles, and nictitating membranes, respectively) with a more rapid onset time than vecuronium (Cay-15603). Formulations containing...

Pancuronium is an aminosteroid antagonist of muscle-type nicotinic acetylcholine receptors (nAChRs) with an IC50 value of 14.8 nM using patch clamp electrophysiology in BOSC23 cells expressing mouse nAChRs. It acts as a non-depolarizing neuromuscular blocking agent. Pancuronium enhances anesthesia induced by...

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Cholinergic receptor, nicotinic, beta 1, ACHRB Protein function: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to...

A nonpolarizing neuromuscular relaxant.

Atracurium (besylate) is a benzylisoquinoline that acts as a neuromuscular blocking agent with slow onset and intermediate duration. It causes non-depolarizing block of the neuromuscular junction.Formal Name:...

Mivacurium is an antagonist of nicotinic acetylcholine receptors (nAChRs) and muscarinic M2 and M3 receptors (ED50s = 0.08, 0.3, and 0.1 mg/kg for ex vivo human skeletal muscle nAChRs, guinea pig cardiac M2 receptors, and guinea pig bronchial M3 receptors, respectively). It inhibits acetylcholine-induced activation...

Succinylcholine is an agonist of muscle-type nicotinic acetylcholine receptors (nAChRs). It activates the muscle-type alpha1beta1deltaepsilon subunit-containing nAChR (EC50 = 10.8 µM in X. laevis oocytes expressing the human receptor) then induces desensitization of the receptor. It is selective for the muscle-type...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat CHRNb1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat CHRNb1. Next,...

Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...

Host Species: Rabbit. Isotype: IgG. Buffer: Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: >95%, Protein G purified. Target Name: CHRNB1. Antigen Species: Human