25 products were found matching "K04804"!

(±)-Nicotine-d3 is intended for use as an internal standard for the quantification of (±)-nicotine (Cay-16535) by GC- or LC-MS. (±)-Nicotine is the racemic mixture of the dominant alkaloid found in tobacco plants. It acts as an agonist at neuronal nicotinic acetylcholine receptors (nAChRs, Kis = 481 and 11.1 nM for...

Chlorisondamine is an antagonist of nicotinic acetylcholine receptors (nAChRs, IC50 = 1.8 µM in rat striatal synaptosomes) and a ganglion blocker. It decreases dopamine release induced by nicotine (Cay-16535, Cay-20887) in a dose-dependent manner in rat striatal synaptosomes at concentrations ranging from 0-100 µM....

Cisatracurium is a competitive antagonist of nicotinic acetylcholine receptors (nAChRs) and non-depolarizing muscle relaxant. It inhibits stimulation of human adult muscle nAChRs by acetylcholine (Cay-23829) with an IC50 value of 10 nM. It also inhibits mouse nAChRs with IC50 values of 54 and 115 nM for adult and...

Hexamethonium is a peripherally-acting nondepolarizing neuromuscular blocking agent that acts as an antagonist of nicotinic acetylcholine receptors (nAChRs). It decreases acetylcholine release induced by carbamoylcholine (Cay-14486) in isolated cat superior cervical ganglion when used at concentrations of 27.4 and...

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CHRNA2. Antigen Species: Human

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CHRNA2. Antigen Species: Human

Description: long lasting nicotinic antagonist. Target: Others. Smiles: ClC1=C(Cl)C(C[N+](C2)(CC[N+](C)(C)C)C)=C2C(Cl)=C1Cl.[I-].[I-]. References: Dietlein F, Kalb B2, Jokic M et al.A Synergistic Interaction between Chk1- and MK2 Inhibitors in KRAS-Mutant Cancer.Cell. 2015 Jul 2,162(1):146-59.

Polyclonal Antibody against Human CHRNA2, Gene description: cholinergic receptor nicotinic alpha 2 subunit, Validated applications: ICC, Uniprot ID: Q15822, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C. Protein function: After binding acetylcholine, the AChR responds by an...

An a4ß2 subunit-containing nAChR agonist, selectively induces rubidium ion efflux in M10 cells expressing a4ß2 subunit-containing nAChRs (EC50 = 0.73 µM for the chicken channels) over M10 cells expressing a3ß4- or a1ß1?d subunit-containing receptors (EC50s = >1,000 nM for both for the chicken channels) and a panel...

Polyclonal Antibody against Human CHRNA2, Gene description: cholinergic receptor nicotinic alpha 2 subunit, Validated applications: ICC, Uniprot ID: Q15822, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C. Protein function: After binding acetylcholine, the AChR responds by an...

Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels formed by a pentameric arrangement of alpha and beta subunits to create distinct muscle and neuronal receptors. Neuronal receptors are found throughout the peripheral and central nervous system where they are involved in fast synaptic...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat CHRNA2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat CHRNA2. Next,...