23 products were found matching "K04804"!

An a4ß2 subunit-containing nAChR agonist, selectively induces rubidium ion efflux in M10 cells expressing a4ß2 subunit-containing nAChRs (EC50 = 0.73 µM for the chicken channels) over M10 cells expressing a3ß4- or a1ß1?d subunit-containing receptors (EC50s = >1,000 nM for both for the chicken channels) and a panel...

(±)-Nicotine-d3 is intended for use as an internal standard for the quantification of (±)-nicotine (Cay-16535) by GC- or LC-MS. (±)-Nicotine is the racemic mixture of the dominant alkaloid found in tobacco plants. It acts as an agonist at neuronal nicotinic acetylcholine receptors (nAChRs, Kis = 481 and 11.1 nM for...

Chlorisondamine is an antagonist of nicotinic acetylcholine receptors (nAChRs, IC50 = 1.8 µM in rat striatal synaptosomes) and a ganglion blocker. It decreases dopamine release induced by nicotine (Cay-16535, Cay-20887) in a dose-dependent manner in rat striatal synaptosomes at concentrations ranging from 0-100 µM....

Cisatracurium is a competitive antagonist of nicotinic acetylcholine receptors (nAChRs) and non-depolarizing muscle relaxant. It inhibits stimulation of human adult muscle nAChRs by acetylcholine (Cay-23829) with an IC50 value of 10 nM. It also inhibits mouse nAChRs with IC50 values of 54 and 115 nM for adult and...

Hexamethonium is a peripherally-acting nondepolarizing neuromuscular blocking agent that acts as an antagonist of nicotinic acetylcholine receptors (nAChRs). It decreases acetylcholine release induced by carbamoylcholine (Cay-14486) in isolated cat superior cervical ganglion when used at concentrations of 27.4 and...

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CHRNA2. Antigen Species: Human

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CHRNA2. Antigen Species: Human

Description: long lasting nicotinic antagonist. Target: Others. Smiles: ClC1=C(Cl)C(C[N+](C2)(CC[N+](C)(C)C)C)=C2C(Cl)=C1Cl.[I-].[I-]. References: Dietlein F, Kalb B2, Jokic M et al.A Synergistic Interaction between Chk1- and MK2 Inhibitors in KRAS-Mutant Cancer.Cell. 2015 Jul 2,162(1):146-59.

Polyclonal Antibody against Human CHRNA2, Gene description: cholinergic receptor nicotinic alpha 2 subunit, Validated applications: ICC, Uniprot ID: Q15822, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C. Protein function: After binding acetylcholine, the AChR responds by an...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat CHRNA2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat CHRNA2. Next,...

Component of neuronal acetylcholine receptors (nAChRs) that function as pentameric, ligand-gated cation channels with high calcium permeability among other activities. nAChRs are excitatory neurotrasnmitter receptors formed by a collection of nAChR subunits known to mediate synaptic transmission in the nervous...

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....