38 products were found matching "K04803"!

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human CHRNa1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human CHRNa1....

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat CHRNa1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat CHRNa1. Next,...

A nonpolarizing neuromuscular relaxant.

Atracurium (besylate) is a benzylisoquinoline that acts as a neuromuscular blocking agent with slow onset and intermediate duration. It causes non-depolarizing block of the neuromuscular junction.Formal Name:...

(±)-Nicotine-d3 is intended for use as an internal standard for the quantification of (±)-nicotine (Cay-16535) by GC- or LC-MS. (±)-Nicotine is the racemic mixture of the dominant alkaloid found in tobacco plants. It acts as an agonist at neuronal nicotinic acetylcholine receptors (nAChRs, Kis = 481 and 11.1 nM for...

Rocuronium is a non-depolarizing muscle relaxant. It selectively induces neuromuscular blockade in cats (ED50s = 153, 185, 1,329, and 4,119 µg/kg for tibialis, soleus, and vagus muscles, and nictitating membranes, respectively) with a more rapid onset time than vecuronium (Cay-15603). Formulations containing...

Pancuronium is an aminosteroid antagonist of muscle-type nicotinic acetylcholine receptors (nAChRs) with an IC50 value of 14.8 nM using patch clamp electrophysiology in BOSC23 cells expressing mouse nAChRs. It acts as a non-depolarizing neuromuscular blocking agent. Pancuronium enhances anesthesia induced by...

TMB 8 is a non-competitive antagonist of nicotinic acetylcholine receptors (nAChRs) with IC50 values of 390 and 350 nM, respectively, for human muscle-type and alpha3beta4 subunit-containing ganglionic nAChRs expressed in TE671/RD or SH-SY5Y cells. It inhibits nicotine-induced dopamine release from rat brain...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. AChR alpha, also called CHRNA, is mapped on 2q24-q32. This gene encodes the alpha subunit of the muscle acetylcholine receptor, which is the main target of pathogenic autoantibodies in autoimmune myasthenia gravis. The protein-coding sequence of the human alpha...

Chlorisondamine is an antagonist of nicotinic acetylcholine receptors (nAChRs, IC50 = 1.8 µM in rat striatal synaptosomes) and a ganglion blocker. It decreases dopamine release induced by nicotine (Cay-16535, Cay-20887) in a dose-dependent manner in rat striatal synaptosomes at concentrations ranging from 0-100 µM....

Mivacurium is an antagonist of nicotinic acetylcholine receptors (nAChRs) and muscarinic M2 and M3 receptors (ED50s = 0.08, 0.3, and 0.1 mg/kg for ex vivo human skeletal muscle nAChRs, guinea pig cardiac M2 receptors, and guinea pig bronchial M3 receptors, respectively). It inhibits acetylcholine-induced activation...

An aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anesthesia to facilitate endotraceal intubation.