43 products were found matching "K04741"!

In 1X PBS, pH 7.4, with 0.09% sodium azide. Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates...

Protein function: Involved in the activation cascade of caspases responsible for apoptosis execution. [The UniProt Consortium]

Caspase-12 is a member of the ICE/CED-3 family of caspases and is detected as a protein of ~51kDa. Overexpression of caspase-12 in cells induces apoptosis. Capase-12 is localized to the endoplasmatic reticulum (ER) and activated by ER stress and specifically cleaves and activates pro-caspase-9 and is also thought to...

Anti-Caspase-12 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Caspase-12 from other sources has not been determined. Protein function: Involved in the activation cascade of caspases responsible for apoptosis execution. [The UniProt Consortium]

Anti-Caspase-12 Antibody is (Large)affinity chromatography purified via peptide column. Cross reactivity with Caspase-12 (Large) from other sources has not been determined. Protein function: Involved in the activation cascade of caspases responsible for apoptosis execution. [The UniProt Consortium]

Anti-Caspase-12 Antibody is (Small)affinity chromatography purified via peptide column. Cross reactivity with Caspase-12 (Small) from other sources has not been determined. Protein function: Involved in the activation cascade of caspases responsible for apoptosis execution. [The UniProt Consortium]

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Caspase-12 is an enzyme known as a cysteine protease. It belongs to a family of enzymes called caspases that cleave their substrates at C-terminal aspartic acid residues. The CASP12 gene was mapped to chromosome 11q22.3. Caspase-12 attenuates the inflammatory...

Protein function: Involved in the activation cascade of caspases responsible for apoptosis execution. [The UniProt Consortium]

Protein function: Involved in the activation cascade of caspases responsible for apoptosis execution. [The UniProt Consortium]

Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum...

Protein function: Has no protease activity. May reduce cytokine release in response to bacterial lipopolysaccharide during infections. Reduces activation of NF-kappa-B in response to TNF. [The UniProt Consortium]