18 products were found matching "K04710"!

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Fumonisin B1
Fumonisin B1

Item number: Cay62580-1

Fumonisin B1 (FB1) is a mycotoxin that has been found in F. moniliforme. It inhibits ceramide synthase (IC50 = 0.1 µM for the rat liver enzyme). FB1 induces DNA fragmentation and apoptosis in CV-1 cells when used at concentrations of 5 and 25 µM, respectively. It is cytotoxic to primary rat hepatocytes and induces...
Keywords: FB1, (2R,2'R)-1,2,3-propanetricarboxylic acid,...
Application: Ceramide synthase inhibitor
CAS 116355-83-0
MW: 721.8 D
From 98.00€ *
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C14 Ceramide (d18:1/14:0)
C14 Ceramide (d18:1/14:0)

Item number: Cay22531-1

C14 Ceramide is an endogenous ceramide generated by ceramide synthase 6. During nutrient-deprivation-induced necroptosis in MEF cells, C14 ceramide levels increase in a time-dependent manner. C14 ceramide plasma levels were reduced in obese patients with or without diabetes following a 12-week supervised exercise...
Keywords: C14 Ceramide, Cer(d18:1/14:0), Ceramide (d18:1/14:0),...
Application: Endogenous ceramide
CAS 34227-72-0
MW: 509.9 D
From 20.00€ *
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740 Y-P
740 Y-P

Item number: Cay22598-1

740 Y-P is a synthetic phosphopeptide activator of PI3K. It contains amino acids from the Antennapedia protein, which acts as a cellular internalization sequence, followed by a sequence from PDGFR that is recognized by the SH2 domain of PI3K. 740 Y-P (15 µM) increases phosphorylation of PI3K, mammalian target of...
Keywords: L-arginyl-L-glutaminyl-L-isoleucyl-L-lysyl-L-isoleucyl-L-tryptophyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-L-arginyl-L-...
Application: Endogenous bioactive sphingolipid
CAS 1236188-16-1
MW: 3270.7 D
From 163.00€ *
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C10 Ceramide (d18:1/10:0)
C10 Ceramide (d18:1/10:0)

Item number: Cay22529-5

C10 ceramide is an endogenous, bioactive sphingolipid produced by ceramide synthase. C10 ceramide inhibits growth of wild-type and MDR1 gene-transfected MDA435/LCC6 human breast cancer cells with IC50 values of 44.1 and 46 µM, respectively. It also inhibits the growth of J774 murine macrophages in a dose-dependent...
Keywords: C10 Ceramide, Cer(d18:1/10:0), Ceramide (d18:1/10:0), N-decanoyl-D-erythro-Sphingosine,...
Application: Endogenous bioactive sphingolipid
CAS 111122-57-7
MW: 453.7 D
From 110.00€ *
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C16 Ceramide-d7 (d18:1-d7/16:0)
C16 Ceramide-d7 (d18:1-d7/16:0)

Item number: Cay22787-1

C16 Ceramide-d7 is intended for use as an internal standard for the quantification of C16 ceramide (d18:1/16:0) by GC- or LC-MS. C16 Ceramide is a sphingolipid. It incorporates into the mitochondrial outer membrane and forms channels that increase its permeability. C16 Ceramide levels are increased by PPMP or MAPP...
Keywords: Ceramide-d7 (d18:1-d7/16:0), Cer-d7 (d18:1-d7/16:0), N-Palmitoyl-D-erythro-Sphingosine-d7, Palmitoyl Ceramide-d7,...
Application: GC-MS, LC-MS, Internal standard
CAS 1840942-13-3
MW: 545 D
From 488.00€ *
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Anti-LASS1, Internal
Anti-LASS1, Internal

Item number: ARG64713.100

Protein function: May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked stearoyl- (C18) ceramide) in a fumonisin B1-independent manner. [The UniProt Consortium]
Keywords: Anti-LAG1, Anti-CERS1, Anti-CerS1, Anti-Protein UOG-1, Anti-Ceramide synthase 1, Anti-LAG1 longevity assurance homolog 1,...
Application: ELISA, WB
Host: Goat
Species reactivity: human
784.00€ *
Review
Anti-LASS1
Anti-LASS1

Item number: NSJ-R34378-100UG

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: LAG1, CerS1 antibody, Ceramide synthase 1 Protein function: May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the...
Keywords: Anti-LAG1, Anti-CERS1, Anti-CerS1, Anti-Protein UOG-1, Anti-Ceramide synthase 1, Anti-LAG1 longevity assurance homolog 1,...
Application: WB, ELISA (peptide)
Host: Goat
Species reactivity: human
755.00€ *
Review
Fumonisin B1
Fumonisin B1

Item number: LKT-F8149.1

A mycotoxin isolated from Fusarium moniliforme. This compound induces apoptosis in rat and monkey kidney cells.
Application: Apoptosis inducer
CAS 116355-83-0
MW: 721,83 D
From 415.00€ *
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Fumonisin B1
Fumonisin B1

Item number: F9575-02.1

Fumonisin is a group of toxins (B1 or FB1, B2 or FB2, which are equally toxic, and B3 or FB3, which is relatively nontoxic) which are produced by fungi (Fusarium moniliforme and F. proliferatum) that causes equine leukoencephalomalacia, a disease of the central nervous system of equines and is associated with the...
CAS 116355-83-0
From 393.00€ *
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Fumonisin B2
Fumonisin B2

Item number: LKT-F8150.1

A Mycotoxin isolated from Fusarium moniliforme. This compound is an inhibitor of the enzyme spingosine acyltransferase.
Keywords: FB2
Application: Sphingosine acyltransferase inhibitor
CAS 116355-84-1
MW: 705,8 D
From 887.00€ *
Review
Anti-CERS1
Anti-CERS1

Item number: G-PACO19924.50

CERS1 Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human, Mouse and for use in ELISA, WB, IHC applications. CERS1 Antibody is a high quality polyclonal antibody for research use only.. Protein function: Ceramide synthase that catalyzes formation of ceramide from sphinganine and...
Keywords: Anti-CerS1, Anti-Protein UOG-1, Anti-Ceramide synthase 1, Anti-LAG1 longevity assurance homolog 1, Anti-Longevity...
Application: ELISA, WB, IHC
Host: Rabbit
Species reactivity: human, mouse
363.00€ *
Review
Anti-CERS1
Anti-CERS1

Item number: G-PACO54854.50

CERS1 Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human, Rat and for use in ELISA, WB, IHC applications. CERS1 Antibody is a high quality polyclonal antibody for research use only.. Protein function: Ceramide synthase that catalyzes formation of ceramide from sphinganine and...
Keywords: Anti-CerS1, Anti-Protein UOG-1, Anti-Ceramide synthase 1, Anti-LAG1 longevity assurance homolog 1, Anti-Longevity...
Application: ELISA, WB, IHC
Host: Rabbit
Species reactivity: human, rat
363.00€ *
Review
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