78 products were found matching "K04675"!

Recombinant human ALK2 (PF197_198L) (activin receptor-like kinase-2), encompassing amino acids 147-end with a PF197_198L mutation. This construct contains an N-terminal GST-tag. The recombinant protein was affinity purified and is active.

Recombinant human ALK2 (Q207D) (activin receptor-like kinase-2), encompassing amino acids 147-end with a Q207D mutation. This construct contains an N-terminal GST-tag. The recombinant protein was affinity purified and is active.

Recombinant human ALK2 (Q207E) (activin receptor-like kinase-2), encompassing amino acids 147-end with a Q207E mutation. This construct contains an N-terminal GST-tag. The recombinant protein was affinity purified and is active

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human ACVR1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human ACVR1. Next,...

Recombinant human ALK2 (G328E) (activin receptor-like kinase-2), encompassing amino acids 147-end with a G328E mutation. This construct contains an N-terminal GST-tag. The recombinant protein was affinity purified and is active.

Recombinant human ALK2 (G328V) (activin receptor-like kinase-2), encompassing amino acids 147-end with a G328V mutation. This construct contains an N-terminal GST-tag. The recombinant protein was affinity purified and is active.

Recombinant human ALK2 (G328W) (activin receptor-like kinase-2), encompassing amino acids 147-end with a G328W mutation. This construct contains an N-terminal GST-tag. The recombinant protein was affinity purified and is active.

Recombinant human ALK2 (G356D) (activin receptor-like kinase-2), encompassing amino acids 147-end with a G356D mutation. This construct contains an N-terminal GST-tag. The recombinant protein was affinity purified and is active.

Bone morphogenetic proteins (BMP) are secreted signaling proteins, many of which are involved in various developmental processes, in addition to bone formation. DMH1 is an analog of the non-selective BMP receptor inhibitor dorsomorphin (Cay-11967) that potently inhibits the kinase activity of activin receptor-like...

LDN-193189 inhibits SMAD1/5/8 phosphorylation by the bone morphogenetic protein (BMP) type I receptors, which are known as activin receptor-like kinases (ALKs), with an IC50 value of 4.9 nM. In in vitro kinase assays, it shows specificity for ALK1, 2, 3, and 6 (IC50s = 0.8, 0.8, 5.3, and 16.7 nM, respectively) over...

Normal development and tissue repair are controlled in part by SMADs, a family of intracellular proteins that are activated by signaling via serine/threonine kinase receptors of the TGF-beta superfamily. LDN-193189 inhibits SMAD1/5/8 phosphorylation by the bone morphogenetic protein (BMP) type I receptors, which are...

Activation of bone morphogenetic protein (BMP) type I receptors, also known as activin receptor-like kinases (ALK1-7), leads to the assembly of SMAD complexes, which translocate to the nucleus to induce transcriptional activation important for normal development and tissue repair. K02288 is a 2-aminopyridine-based...