23 products were found matching "K04634"!

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YM-254890
YM-254890

Item number: AG-CN2-0509-MC05

Off-white solid. Soluble in DMSO (10mg/ml). Cyclic depsipeptide composed of unique amino acids differing from normal amino acids, Membrane permeable, potent and selective Galphaq family inhibitor, Inhibits the signal transduction of Galphaq, Galpha11 and Galpha14 (IC50=0.095&mu,M) by blocking the exchange of GDP for...
Keywords: QS 3666A
Application: G alpha q family inhibitor
CAS 568580-02-9
MW: 960,1 D
220.00€ * From 198.00€ *
Review
YM-254890
YM-254890

Item number: Cay29735-1

YM-254890 is cyclic depsipeptide originally isolated from Chromobacterium and an inhibitor of Galphaq/11. It inhibits Galphaq/11-mediated intracellular calcium mobilization induced by 2MeSADP or methacholine in C6-15 cells expressing the purinergic P2Y1 receptor (IC50 = 0.15 µM) and in CHO cells expressing M1...
Keywords: N-acetyl-L-threonyl-(alphaR)-alpha-hydroxybenzenepropanoyl-2,3-didehydro-N-methylalanyl-L-alanyl-N-methyl-L-alanyl-(3R)-3-...
Application: Cyclic depsipeptide Galphaq/11 inhibitor
CAS 568580-02-9
MW: 960.1 D
423.00€ *
Review
FR900359
FR900359

Item number: Cay33666-250

FR900359 is a cyclic depsipeptide that has been found in A. crenata and is an inhibitor of Galphaq, Galpha11, and Galpha14 (IC50s = 13.18, 10.47, and 10 nM, respectively). It is selective for these Galpha subunits over a panel of additional Galpha subunits, including Galphas and Galphai, in bioluminescence resonance...
Keywords: UBO-QIC,...
Application: Cyclic depsipeptide, Galphaq, Galpha11, Galpha14 inhibitor
CAS 107530-18-7
MW: 1002.2 D
From 158.00€ *
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Anti-GNAQ
Anti-GNAQ

Item number: ARG10606.50

Protein function: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM-derived neutrophils and dendritic cells...
Keywords: Anti-GAQ, Anti-GNAQ, Anti-Guanine nucleotide-binding protein alpha-q, Anti-Guanine nucleotide-binding protein G(q) subunit...
Application: IHC (paraffin), WB
Host: Rabbit
Species reactivity: human, mouse, rat
528.00€ *
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Anti-GNAQ
Anti-GNAQ

Item number: NSJ-R32120

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Guanine nucleotide-binding protein G(q) subunit alpha is a protein that in humans is encoded by the GNAQ gene. Guanine nucleotide-binding proteins are a family of heterotrimeric proteins that couple cell surface, 7-transmembrane domain receptors to intracellular...
Keywords: Anti-GAQ, Anti-GNAQ, Anti-Guanine nucleotide-binding protein alpha-q, Anti-Guanine nucleotide-binding protein G(q) subunit...
Application: WB, IHC (paraffin)
Host: Rabbit
Species reactivity: human, mouse, rat
755.00€ *
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Anti-GNAQ
Anti-GNAQ

Item number: NSJ-R34779-100UG

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: ALPHA-q, Guanine nucleotide binding protein, G-ALPHA-q, GAQ Protein function: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane...
Keywords: Anti-GAQ, Anti-GNAQ, Anti-Guanine nucleotide-binding protein alpha-q, Anti-Guanine nucleotide-binding protein G(q) subunit...
Application: WB, ELISA (peptide)
Host: Goat
Species reactivity: human, mouse, rat, swine
755.00€ *
Review
Anti-G.alpha.q
Anti-G.alpha.q

Item number: NB-21014

Concentration: 0.2 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Background: Heterotrimeric G proteins are essential cellular signal transducers.Galphaq is a member of the Gq subfamily of G proteins. Galphaq is known to stimulate phospholipase C. Other biochemical and...
Keywords: Anti-GAQ, Anti-GNAQ, Anti-Guanine nucleotide-binding protein alpha-q, Anti-Guanine nucleotide-binding protein G(q) subunit...
Application: ELISA, WB
Host: Rabbit
Species reactivity: vertebrates
317.00€ *
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Anti-GNAQ, clone GNAQ/2434
Anti-GNAQ, clone GNAQ/2434

Item number: NSJ-V7813-100UG

0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. GNAQ is 359 amino acids long and is identical in all but 1 amino acid residue to the Mouse protein. Analysis of human genomic DNA revealed an intronless sequence with strong homology to human GNAQ cDNA. In comparison to GNAQ cDNA, this genomic DNA...
Keywords: Anti-GAQ, Anti-GNAQ, Anti-Guanine nucleotide-binding protein alpha-q, Anti-Guanine nucleotide-binding protein G(q) subunit...
Application: ELISA, FC, IF
Host: Mouse
Species reactivity: human
From 332.00€ *
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Anti-GNAQ, clone GNAQ/2434
Anti-GNAQ, clone GNAQ/2434

Item number: NSJ-V7813SAF-100UG

1 mg/ml in 1X PBS, BSA free, sodium azide free. GNAQ is 359 amino acids long and is identical in all but 1 amino acid residue to the Mouse protein. Analysis of human genomic DNA revealed an intronless sequence with strong homology to human GNAQ cDNA. In comparison to GNAQ cDNA, this genomic DNA sequence included...
Keywords: Anti-GAQ, Anti-GNAQ, Anti-Guanine nucleotide-binding protein alpha-q, Anti-Guanine nucleotide-binding protein G(q) subunit...
Application: ELISA, FC, IF
Host: Mouse
Species reactivity: human
752.00€ *
Review
Anti-Guanine nucleotide-binding protein alpha-q / GNAQ / G-ALPHA-q Monoclonal Antibody (Clone: GNAQ/
Anti-Guanine nucleotide-binding protein alpha-q / GNAQ /...

Item number: ABE-36-2400-100

GNAQis 359 amino acids long and is identical in all but 1 amino acid residue to the Mouse protein. Analysis of human genomic DNA revealed an intronless sequence with strong homology to human GNAQ cDNA. In comparison to GNAQ cDNA, this genomic DNA sequence included several small deletions and insertions that altered...
Keywords: Anti-GAQ, Anti-GNAQ, Anti-Guanine nucleotide-binding protein alpha-q, Anti-Guanine nucleotide-binding protein G(q) subunit...
Application: ELISA, FC, IF
Host: Mouse
Species reactivity: human
From 375.00€ *
Review
BIM-46187 (hydrochloride)
BIM-46187 (hydrochloride)

Item number: Cay34531-25

BIM-46187 is an inhibitor of heterotrimeric G-protein signaling. It inhibits signaling through Galphai, Galphas, and Galphaq in MZ7 cells but selectively inhibits Galphaq in HEK293 and CHO cells, indicating cell-dependent inhibition. BIM-46187 (0.1-1 mg/kg) increases the paw withdrawal threshold to a mechanical...
Keywords: (2R,2'R)-3,3'-dithiobis[2-amino-1-[(8S)-8-(cyclohexylmethyl)-5,6-dihydro-2-phenylimidazo[1,2-a]pyrazin-7(8H)-yl]-1-propano...
Application: Heterotrimeric G-protein signaling inhibitor
CAS 2489449-03-6
MW: 941 D
From 66.00€ *
Review
Anti-GNAQ
Anti-GNAQ

Item number: G-CAB14736.100

WB 1:500 - 1:2000. Protein function: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM-derived neutrophils...
Keywords: Anti-GAQ, Anti-GNAQ, Anti-Guanine nucleotide-binding protein alpha-q, Anti-Guanine nucleotide-binding protein G(q) subunit...
Application: WB
Host: Rabbit
Species reactivity: human, mouse, rat
From 352.00€ *
Review
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