76 products were found matching "K04612"!
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CASR (human), recombinant protein
Item number: ABS-PP-287.20
| Keywords: | Extracellular calcium-sensing receptor, CaR, CaSR, hCasR, Parathyroid cell calcium-sensing receptor 1, PCaR1, Recombinant... |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 24 kD |
From 90.00€
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Cinacalcet
Item number: TGM-T8403-50mg
Description: Cinacalcet (AMG 073) is an orally active, allosteric Ca receptor (CaR) agonist used in the treatment of cardiovascular disease. Target: CaSR. Smiles: [C@@H](NCCCC1=CC(C(F)(F)F)=CC=C1)(C)C=2C3=C(C=CC2)C=CC=C3. References: D.A. Bushinsky, et al. Effect of cinacalcet on urine calcium excretion and...
| Keywords: | AMG 073 |
| Application: | Targets calcium-sensing receptor (CASR) |
| CAS | 226256-56-0 |
| MW: | 357.41 D |
From 43.00€
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CASR Protein, Human, Recombinant (GST)
Item number: TGM-TMPH-01315-100ug
Description: CASR Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 93.6 kDa and the accession number is P41180.
| Keywords: | Apoptotic protease Mch-5, FLICE, Apoptotic cysteine protease, FADD-like ICE, FADD-homologous ICE/ced-3-like protease,... |
| MW: | 93.6 kD |
From 198.00€
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Etelcalcetide
Item number: TGM-TP1235-10mg
Description: Etelcalcetide (AMG 416) is a synthetic peptide that serves as an activator of the calcium-sensing receptor (CaSR) and is used as a calcimimetic drug for treating secondary hyperparathyroidism in patients undergoing hemodialysis. Smiles:...
| Keywords: | KAI-4169, AMG 416 |
| Application: | Targets calcium-sensing receptor (CASR) |
| CAS | 1262780-97-1 |
| MW: | 1048.26 D |
From 49.00€
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Etelcalcetide hydrochloride
Item number: TGM-TP1236-100mg
Description: Etelcalcetide hydrochloride (AMG 416 hydrochloride) is a synthetic peptide that serves as an allosteric modulator of the calcium-sensing receptor (CaSR), effectively reducing parathyroid hormone (PTH) levels in patients with secondary hyperparathyroidism undergoing hemodialysis. Target: CaSR. Smiles:...
| Keywords: | KAI-4169 hydrochloride, AMG 416 hydrochloride |
| Application: | Targets calcium-sensing receptor (CASR) |
| CAS | 1334237-71-6 |
| MW: | 1353.33 D |
From 31.00€
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Tecalcet Hydrochloride
Item number: TGM-T13918-100mg
Description: Tecalcet Hydrochloride (R-568 hydrochloride) is an allosteric and positive modulator of the calcium-sensing receptor(CaSR). Tecalcet Hydrochloride increases the sensitivity to the activation of extracellular Ca2+. Target: CaSR. Smiles: Cl.COc1cccc(c1)[C@@H](C)NCCCc1ccccc1Cl. References: Wada, M., et al....
| Keywords: | R-568 hydrochloride, R-568 (hydrochloride) |
| Application: | Targets calcium-sensing receptor (CASR) |
| CAS | 177172-49-5 |
| MW: | 340.29 D |
From 31.00€
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Evocalcet
Item number: TGM-T15261-100mg
Description: Evocalcet (KHK7580) has an activating effect on the calcium-sensing receptor (CaSR). Target: CaSR. Smiles: C[C@@H](N[C@H]1CCN(C1)c1ccc(CC(O)=O)cc1)c1cccc2ccccc12. References: Tanimura, Shinji, et al. Pharmaceutical composition containing aryl alkyl amine compound. WO 2017061621 A1.
| Keywords: | KHK7580 |
| Application: | Targets calcium-sensing receptor (CASR) |
| CAS | 870964-67-3 |
| MW: | 374.48 D |
From 31.00€
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Calindol hydrochloride
Item number: TGM-T21758-1mg
Description: Calindol hydrochloride is a potent orthosteric modulator (EC50: 132 nM) of the putative calcium-calcium-sensitive receptor (CaSR), inhibits Pi-induced VC, and delays the progression of calcification in vascular smooth muscle cells. Target: CaSR. Smiles: Cl.C[C@@H](NCc1cc2ccccc2[nH]1)c1cccc2ccccc12....
| Application: | Calcimimetic |
| CAS | 729610-18-8 |
| MW: | 336.86 D |
From 45.00€
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Upacicalcet
Item number: TGM-T29067-100mg
Description: Upacicalcet (AJT-240) is an intraventricular calcium mimetic, a SHPT available for human hemodialysis, that inhibits excessive parathyroid hormone (PTH) secretion by directly acting on parathyroid cell membrane calcium-sensitive receptors, thereby lowering blood levels of PTH.Upacicalcet is an...
| Keywords: | PLS-240, SK-1403, AJT-240 |
| Application: | Targets calcium-sensing receptor (CASR) |
| CAS | 1333218-50-0 |
| MW: | 351.76 D |
From 108.00€
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AC265347
Item number: TGM-T29541-1mg
Description: AC265347 is a potent calcium-sensitive receptor (CaSR) agonist and ago-PAM orthosteric modulator with antitumour activity that inhibits neuroblastoma tumour growth by inducing differentiation.AC265347 can be used to study neuroblastoma. Target: CaSR. Smiles: OC(C1=NC=2C=CC=CC2S1)(C3=CC=C(C=C3C)C)C....
| Keywords: | AC-265347 |
| Application: | Calcimimetic, positive allosteric CaSR modulator |
| CAS | 1253901-26-6 |
| MW: | 283.39 D |
From 33.00€
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Ronacaleret HCl
Item number: TGM-T34385-100mg
Description: Ronacaleret HCl (SB-751689) is a small molecule CaSR antagonist for the treatment of endocrine and metabolic diseases, skin and musculoskeletal disorders. Target: CaSR. Smiles: C(C(NC[C@H](COC1=CC(CCC(O)=O)=CC(F)=C1F)O)(C)C)C2CC=3C(C2)=CC=CC3.Cl. References: Fitzpatrick LA, et al. The effects of...
| Keywords: | SB 751689, SB751689, SB-751689A, SB 751689A, SB-751689, SB751689A |
| Application: | Targets calcium-sensing receptor (CASR) |
| CAS | 702686-96-2 |
| MW: | 483.98 D |
From 289.00€
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NPS-2143 hydrochloride
Item number: TGM-T4967-100mg
Description: NPS-2143 hydrochloride (NPS-2143 HCL) is a selective potent calcium ion-sensing receptor antagonist. Target: CaSR. Smiles: Cl.CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)COc1cccc(Cl)c1C#N. References: Marquis, Robert W., Lago, Amparo M., Callahan, James F.,Antagonists of the Calcium Receptor. 2. Amino...
| Keywords: | NPS-2143 HCL |
| Application: | CaSR antagonist |
| CAS | 324523-20-8 |
| MW: | 445.38 D |
From 40.00€
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