The following products have been found matching your search "K04608": 33

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O-Phospho-L-Serine
O-Phospho-L-Serine

Item number: Cay16151-5

O-Phospho-L-Serine is an agonist of the group III metabotropic glutamate receptors mGluR4a and mGluR6 (EC50s = 2-5 µM). It mimics the phosphatidylserine head group and has been shown to inhibit the proliferation of microglia and to enhance neuronal differentiation of progenitor cells.
Keywords: Dexfosfoserine, L-Serine-O-Phosphate, L-SOP, O-phosphono-L-serine
Application: MGluR4 / mGluR6 agonist
CAS 407-41-0
MW: 185.1 D
From 24.00€ *
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(±)-trans-ACPD
(±)-trans-ACPD

Item number: Cay28849-5

(±)-trans-ACPD is an agonist of metabotropic glutamate receptors (mGluRs, EC50s = 15, 2, 40, 23, and 82 µM for mGluR1, -2, -3, -5, and -6, respectively, in CHO cells expressing recombinant receptors). It also activates mGluR4 in baby hamster kidney cells with an EC50 value of approximately 800 µM. (±)-trans-ACPD...
Keywords: (1R,3S)-1-aminocyclopentane-1,3-dicarboxylic acid
Application: MGluR agonist
CAS 67684-64-4
MW: 173.2 D
From 37.00€ *
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(S)-MCPG
(S)-MCPG

Item number: Cay21450-25

(S)-MCPG is an antagonist of metabotropic glutamate receptors (mGluRs) and the active component of (±)-MCPG, which is selective for Group I and Group II mGluRs. (S)-MCPG inhibits motoneuron depolarization induced by 1-amino-1,3-dicarboxycyclopentane (ACPD) in neonatal rat spinal cord in vitro and ACPD-induced...
Keywords: (S)-alpha-methyl-4-Carboxyphenylglycine, alphaS-amino-4-carboxy-alpha-methyl-benzeneacetic acid
Application: Non-selective group I/group II metabotropic glutamate receptor antagonist
CAS 150145-89-4
MW: 209.2 D
From 67.00€ *
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Anti-phospho-mGluR7 (Ser862)
Anti-phospho-mGluR7 (Ser862)

Item number: 600-401-D78

Anti mGluR7 pS862 antibodiy is directed against mGluR7 phosphorylated at Ser862. GluR7 antibdody is affinity purified from monospecific antiserum by immunoaffinity purification. Immunolabeling is blocked by preadsorption of antibody with the phospho-peptide used as antigen but not by the corresponding...
Keywords: Anti-phospho-Grm7, Anti-phospho-Gprc1g, Anti-phospho-mGluR7, Anti-phospho-Metabotropic glutamate receptor 7
Application: WB
Reactivity: Rat, Mouse
489.00€ *
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Anti-GRM7
Anti-GRM7

Item number: NSJ-R34771-100UG

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Glutamate receptor, metabotropic 7 Protein function: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding...
Keywords: Anti-GRM7, Anti-mGluR7, Anti-GPRC1G, Anti-Metabotropic glutamate receptor 7, GRM7 Antibody
Application: WB, ELISA (peptide)
Reactivity: Human
503.00€ *
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Anti-phospho-Metabotropic Glutamate Receptor 7 (Ser862)
Anti-phospho-Metabotropic Glutamate Receptor 7 (Ser862)

Item number: ARG52340.100

Protein function: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. [The...
Keywords: Anti-phospho-Grm7, Anti-phospho-Gprc1g, Anti-phospho-mGluR7, Anti-phospho-Metabotropic glutamate receptor 7
Application: WB
Reactivity: Mouse, Rat
622.00€ *
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MMPIP (hydrochloride)
MMPIP (hydrochloride)

Item number: Cay18862-1

MMPIP is a reversible allosteric antagonist of the metabotropic glutamate receptor 7 (mGluR7) that blocks agonist-induced calcium mobilization (IC50 = 26 nM). It does not affect other mGlu receptors. The modulation of mGluR7 by MMPIP is context dependent, in that it is not observed in all known mGluR7 signaling...
Keywords: 6-(4-methoxyphenyl)-5-methyl-3-(4-pyridinyl)-isoxazolo[4,5-c]pyridin-4(5H)-one, monohydrochloride
Application: MGluR7 antagonist
CAS 1215566-78-1
MW: 369.8 D
From 69.00€ *
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DCPG
DCPG

Item number: Cay22072-1

DCPG is a selective agonist of the class III metabotropic glutamate receptor 8 (mGluR8), with an EC50 value of 31 nM for inhibiting forskolin-stimulated cAMP formation in AV12-664 cells expressing human mGluR8. It is selective for mGluR8 over other mGluRs (EC50s = >3.5 µM for mGluR1-7). In vitro, DCPG (1 µM)...
Keywords: (S)-3,4-DCPG, 4-[(S)-aminocarboxymethyl]-1,2-benzenedicarboxylic acid
Application: MGluR8a agonist
CAS 201730-11-2
MW: 239.2 D
From 40.00€ *
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ACPT-I
ACPT-I

Item number: Cay78010-10

ACPT-I is an agonist of the group III metabotropic glutamate receptors (mGluRs) mGluR4a and mGluR8 (EC50s = 7.2 and 8.2 µM, respectively) that has no effect on mGluR1a or mGluR2. It has diverse biological activity, including neuroprotective, anticonvulsant, and anxiolytic-like effects. ACPT-I (1-200 µM) reduces cell...
Keywords: 4-amino-1alpha,2alpha,4beta-cyclopentanetricarboxylic acid
Application: MGluR4a / mGluR8 agonist
CAS 194918-76-8
MW: 217.2 D
From 44.00€ *
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Anti-GRM7, Internal
Anti-GRM7, Internal

Item number: ARG64884.100

Protein function: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. [The...
Keywords: Anti-GRM7, Anti-GPRC1G, Anti-mGluR7, Anti-Metabotropic glutamate receptor 7
Application: ELISA, WB
Reactivity: Human
542.00€ *
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XAP044
XAP044

Item number: Cay19095-1

XAP044 is an antagonist of the metabotropic glutamate (mGlu) receptor 7 (mGluR7), inhibiting lateral amygdala long term potentiation in brain slices from wild-type mice with an IC50 value of 88 nM. This effect is absent in mGluR7-deficient mice. XAP044 demonstrates good brain penetrance, producing wide spectrum...
Keywords: 7-hydroxy-3-(4-iodophenoxy)-4H-1-benzopyran-4-one
Application: MGluR7 antagonist
CAS 196928-50-4
MW: 380.1 D
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Anti-GRM7
Anti-GRM7

Item number: ABD-8G367.50

Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity.
Keywords: Anti-GRM7, Anti-mGluR7, Anti-GPRC1G, Anti-Metabotropic glutamate receptor 7
Application: WB, IF, ELISA
Reactivity: Human, Mouse, Rat
221.00€ *
Review
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