49 products were found matching "K04577"!
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Anti-CALCRL
Item number: ATA-HPA008071.100
Rabbit Polyclonal CALCRL Antibody against Human calcitonin receptor like receptor. Validated for Western Blot. Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Interspecies information: Highest antigen sequence indentity to the following orthologs: ENSMUSG00000059588: 86%,...
| Keywords: | Anti-CGRPR, Anti-CALCRL, Anti-CGRP type 1 receptor, Anti-Calcitonin receptor-like receptor, Anti-Calcitonin gene-related... |
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | human |
491.00€
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SB-268262
Item number: Cay43547-10
A nonpeptide CGRP receptor antagonist (IC50 = 0.24 µM in a radioligand binding assay), inhibits CGRP-induced cAMP accumulation in SK-N-MC membrane preparations (IC50 = 0.83 µM). Formulation: A solid. InChI:...
| Keywords: | N-methyl-N-(2-methylphenyl)-3-nitro-4-(2-thiazolylsulfinyl)-benzamide |
| Application: | Nonpeptide CGRP receptor antagonist |
| CAS | 217438-17-0 |
| MW: | 401.46 D |
From 186.00€
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Anti-CALCRL
Item number: E-AB-13173.200
Calcitonin receptor-like (CALCRL), also known as the calcitonin receptor-like receptor (CRLR), is a human protein. The protein encoded by the CALCRL gene is a G protein-coupled receptor related to the calcitonin receptor. CALCRL is linked to one of three single transmembrane domain receptor activity-modifying...
| Keywords: | Anti-CGRPR, Anti-CALCRL, Anti-CGRP type 1 receptor, Anti-Calcitonin receptor-like receptor, Anti-Calcitonin gene-related... |
| Application: | WB, IHC, ELISA |
| Host: | Rabbit |
| Species reactivity: | human |
From 89.00€
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MK-0974
Item number: Cay23960-1
MK-0974 is an orally bioavailable antagonist of the calcitonin gene-related peptide (CGRP) receptor complex (Ki = 0.77 µM), which is composed of the calcitonin receptor-like receptor (CRLR) and receptor activity modifying protein 1 (RAMP1). MK-0974 binds selectively to the human CGRP receptor complex, over the...
| Keywords: | N-[(3R,6S)-6-(2,3-difluorophenyl)hexahydro-2-oxo-1-(2,2,2-trifluoroethyl)-1H-azepin-3-yl]-4-(2,3-dihydro-2-oxo-1H-imidazo[... |
| Application: | CGRPR antagonist |
| CAS | 781649-09-0 |
| MW: | 566.5 D |
From 102.00€
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Human CALCRL (calcitonin receptor-like receptor) ELISA Kit
Item number: G-HUFI03344.96
ELISA Type: Sandwich. Sensitivity: 0.094ng/ml. Range: 0.156-10ng/ml. Protein function: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3. Receptor for adrenomedullin together with RAMP2. The activity of this receptor is mediated by G proteins...
| Keywords: | CGRPR, CALCRL, CGRP type 1 receptor, Calcitonin receptor-like receptor, Calcitonin gene-related peptide type 1 receptor |
| Application: | Sandwich ELISA |
| Species reactivity: | human |
698.00€
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Anti-CALCRL
Item number: ARG41874.100
Protein function: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3. Receptor for adrenomedullin together with RAMP2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. [The UniProt Consortium]
| Keywords: | Anti-CGRPR, Anti-CALCRL, Anti-CGRP type 1 receptor, Anti-Calcitonin receptor-like receptor, Anti-Calcitonin gene-related... |
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
707.00€
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Anti-CALCRL
Item number: ATA-HPA008070.100
Protein function: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3. Receptor for adrenomedullin together with RAMP2 (PubMed:22102369, PubMed:30115739). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase...
| Keywords: | Anti-CGRPR, Anti-CALCRL, Anti-CGRP type 1 receptor, Anti-Calcitonin receptor-like receptor, Anti-Calcitonin gene-related... |
| Application: | IHC |
| Host: | Rabbit |
| Species reactivity: | human |
From 246.00€
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Anti-CALCRL
Item number: ATA-HPA046515.100
Protein function: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3. Receptor for adrenomedullin together with RAMP2 (PubMed:22102369, PubMed:30115739). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase...
| Keywords: | Anti-CGRPR, Anti-CALCRL, Anti-CGRP type 1 receptor, Anti-Calcitonin receptor-like receptor, Anti-Calcitonin gene-related... |
| Application: | ICC |
| Host: | Rabbit |
| Species reactivity: | human |
From 246.00€
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Atogepant
Item number: Cay35899-1
Atogepant is an antagonist of the calcitonin gene-related peptide (CGRP) receptor (IC50 = 0.026 nM). It is selective for the CGRP receptor over the adrenomedullin receptors (AM1) and AM2, calcitonin (CT) receptor, amylin receptor 1 (AMY1), and AMY3 receptor (IC50s = >18,000, 400, 6,274, 2.4 and 1,418 nM,...
| Keywords: | (3'S)-1',2',5,7-tetrahydro-N-[(3S,5S,6R)-6-methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)-3-piperidinyl]-... |
| Application: | CGRP receptor (CALCRL) antagonist |
| CAS | 1374248-81-3 |
| MW: | 603.5 D |
281.00€
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Human CGRPR Protein, hFc Tag
Item number: DIM-PME101375.10
Recombinant human CGRPR Protein with C-terminal human Fc tag. CGRPR(Glu23-Asn140) hFc(Glu99-Ala330), Protein function: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3. Receptor for adrenomedullin together with RAMP2 (PubMed:22102369,...
| Keywords: | CRLR, CALCRL, LMPHM8 |
| Expressed in: | Human cells |
| Origin: | human |
| CAS | 12 |
| MW: | 39.9 kD |
From 110.00€
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Human CGRPR Protein, mFc Tag
Item number: DIM-PME101376.10
Recombinant human CGRPR Protein with C-terminal mouse Fc tag. CGRPR(Glu23-Asn140) mFc(Pro99-Lys330), Protein function: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3. Receptor for adrenomedullin together with RAMP2 (PubMed:22102369,...
| Keywords: | CRLR, CALCRL, LMPHM8 |
| Expressed in: | Human cells |
| Origin: | human |
| CAS | 12 |
| MW: | 40.0 kD |
From 110.00€
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Human CGRPR and RAMP1 Heterodimer Protein, hFc Tag and...
Item number: DIM-PME101404.10
Recombinant human CGRPR protein with C-terminal human Fc tag and human RAMP1 protein with C-terminal mouse Fc tag. CGRPR(Glu23-Asn140) hFc(Glu99-Ala330) and RAMP1(Cys27-Ser117) mFc(Pro99-Lys330), Protein function: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin...
| Keywords: | CRLR, CGRPR, LMPHM8 and RAMP1 |
| Expressed in: | Human cells |
| Origin: | human |
| CAS | 12 |
| MW: | 39.9/ kD |
From 140.00€
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