- Search results for K04577
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31 products were found matching "K04577"!
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Item number: Cay35899-1
Atogepant is an antagonist of the calcitonin gene-related peptide (CGRP) receptor (IC50 = 0.026 nM). It is selective for the CGRP receptor over the adrenomedullin receptors (AM1) and AM2, calcitonin (CT) receptor, amylin receptor 1 (AMY1), and AMY3 receptor (IC50s = >18,000, 400, 6,274, 2.4 and 1,418 nM,...
Keywords: | (3'S)-1',2',5,7-tetrahydro-N-[(3S,5S,6R)-6-methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)-3-piperidinyl]-... |
Application: | CGRP receptor (CALCRL) antagonist |
CAS | 1374248-81-3 |
MW: | 603.5 D |
409.00€
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Item number: G-HDBS0148.100
Protein function: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3. Receptor for adrenomedullin together with RAMP2 (PubMed:22102369, PubMed:30115739). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase...
Keywords: | Anti-CGRPR, Anti-CALCRL, Anti-CGRP type 1 receptor, Anti-Calcitonin receptor-like receptor, Anti-Calcitonin gene-related... |
Application: | FC |
Host: | Human |
Species reactivity: | human |
399.00€
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Item number: Cay23960-1
MK-0974 is an orally bioavailable antagonist of the calcitonin gene-related peptide (CGRP) receptor complex (Ki = 0.77 µM), which is composed of the calcitonin receptor-like receptor (CRLR) and receptor activity modifying protein 1 (RAMP1). MK-0974 binds selectively to the human CGRP receptor complex, over the...
Keywords: | N-[(3R,6S)-6-(2,3-difluorophenyl)hexahydro-2-oxo-1-(2,2,2-trifluoroethyl)-1H-azepin-3-yl]-4-(2,3-dihydro-2-oxo-1H-imidazo[... |
Application: | CGRPR antagonist |
CAS | 781649-09-0 |
MW: | 566.5 D |
From 92.00€
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Item number: E-AB-13173.120
Calcitonin receptor-like (CALCRL), also known as the calcitonin receptor-like receptor (CRLR), is a human protein. The protein encoded by the CALCRL gene is a G protein-coupled receptor related to the calcitonin receptor. CALCRL is linked to one of three single transmembrane domain receptor activity-modifying...
Keywords: | Anti-CGRPR, Anti-CALCRL, Anti-CGRP type 1 receptor, Anti-Calcitonin receptor-like receptor, Anti-Calcitonin gene-related... |
Application: | WB, IHC, ELISA |
Host: | Rabbit |
Species reactivity: | human |
From 71.00€
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Item number: G-HUFI03344.96
ELISA Type: Sandwich. Sensitivity: 0.094ng/ml. Range: 0.156-10ng/ml. Protein function: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3. Receptor for adrenomedullin together with RAMP2. The activity of this receptor is mediated by G proteins...
Keywords: | CGRPR, CALCRL, CGRP type 1 receptor, Calcitonin receptor-like receptor, Calcitonin gene-related peptide type 1 receptor |
Application: | Sandwich ELISA |
Species reactivity: | human |
641.00€
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Item number: E-AB-63022.120
Protein function: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3. Receptor for adrenomedullin together with RAMP2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. [The UniProt Consortium]
Keywords: | Anti-CGRPR, Anti-CALCRL, Anti-CGRP type 1 receptor, Anti-Calcitonin receptor-like receptor, Anti-Calcitonin gene-related... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 198.00€
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Item number: ARG41874.100
Protein function: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3. Receptor for adrenomedullin together with RAMP2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. [The UniProt Consortium]
Keywords: | Anti-CGRPR, Anti-CALCRL, Anti-CGRP type 1 receptor, Anti-Calcitonin receptor-like receptor, Anti-Calcitonin gene-related... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
624.00€
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Item number: G-CAB11979.100
Application: | WB |
Host: | Rabbit |
Species reactivity: | rat |
From 352.00€
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Item number: G-CAB8533.100
Application: | WB |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 352.00€
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Item number: ATA-HPA008070.100
Protein function: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3. Receptor for adrenomedullin together with RAMP2 (PubMed:22102369, PubMed:30115739). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase...
Keywords: | Anti-CGRPR, Anti-CALCRL, Anti-CGRP type 1 receptor, Anti-Calcitonin receptor-like receptor, Anti-Calcitonin gene-related... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 335.00€
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Item number: ATA-HPA046515.100
Protein function: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3. Receptor for adrenomedullin together with RAMP2 (PubMed:22102369, PubMed:30115739). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase...
Keywords: | Anti-CGRPR, Anti-CALCRL, Anti-CGRP type 1 receptor, Anti-Calcitonin receptor-like receptor, Anti-Calcitonin gene-related... |
Application: | ICC |
Host: | Rabbit |
Species reactivity: | human |
From 335.00€
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Item number: E-AB-93070.120
Receptor for calcitonin-gene-related peptide (CGRP together with RAMP1 and receptor for adrenomedullin together with RAMP3 (By similarity. Receptor for adrenomedullin together with RAMP2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Protein function: Receptor for...
Keywords: | CGRPR, CGRP type 1 receptor, Calcitonin receptor-like receptor, Calcitonin gene-related peptide type 1 receptor, CALCRL... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | mouse, rat |
From 198.00€
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