81 products were found matching "K04504"!

1 from 7 pages
No results were found for the filter!
Bezafibrate
Bezafibrate

Item number: Cay10009145-1

Bezafibrate is a non-selective agonist of peroxisome proliferator-activated receptors (PPARs, EC50s = 50, 60, and 20 µM for human PPARalpha, PPARgamma, and PPARdelta, respectively). It reduces triglyceride levels and the size of lipid droplets in an oleic acid-induced HepaRG hepatocyte model of steatosis when used...
Keywords: Benzofibrate, BM 15075, 2-[4-[2-[(4-chlorobenzoyl)amino]ethyl]phenoxy]-2-methyl-propanoic acid
Application: Non-selective PPAR agonist
CAS 41859-67-0
MW: 361.8 D
From 31.00€ *
Review
Anti-PPARD
Anti-PPARD

Item number: ABS-KC-4033.100

Protein function: Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma- linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter...
Keywords: Anti-Peroxisome proliferator-activated receptor delta, Anti-PPAR-delta, Anti-NUCI, Anti-Nuclear hormone receptor 1,...
Application: IHC
Host: Mouse
Species reactivity: human, rat, mouse
From 206.00€ *
Review
Anti-PPARD
Anti-PPARD

Item number: ABS-KC-4363.100

Protein function: Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma- linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter...
Keywords: Anti-Peroxisome proliferator-activated receptor delta, Anti-PPAR-delta, Anti-NUCI, Anti-Nuclear hormone receptor 1,...
Application: IHC
Host: Mouse
Species reactivity: human, rat, mouse
From 206.00€ *
Review
T0070907
T0070907

Item number: TGM-T6689-10mg

Description: T0070907(IC50=1 nM) , an effective and specific PPARgamma inhibitor, with the >800-fold selectivity over PPARalpha and PPARdelta. Target: PPAR. Smiles: [O-][N+](=O)c1ccc(Cl)c(c1)C(=O)Nc1ccncc1. References: Lee G et al. J Biol Chem, 2002, 277(22), 19649-19657.
Application: PPAR gamma antagonist
CAS 313516-66-4
MW: 277.66 D
From 45.00€ *
Review
GW0742
GW0742

Item number: TGM-T6524-50mg

Description: GW0742 (GW610742) is an effective and specific PPARdelta agonist (EC50: 1 nM/1.1 µM/2 µM, for human PPARdelta/alpha/gamma). Target: PPAR. Smiles: Cc1nc(sc1CSc1ccc(OCC(O)=O)c(C)c1)-c1ccc(c(F)c1)C(F)(F)F. References: Sznaidman ML, et al. Bioorg Med Chem Lett, 2003, 13(9), 1517-1521.
Keywords: GW610742
Application: PPARdelta agonist
CAS 317318-84-6
MW: 471.49 D
From 43.00€ *
Review
Ppard Protein, Human, Recombinant (His)
Ppard Protein, Human, Recombinant (His)

Item number: TGM-TMPH-03755-100ug

Description: Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of...
Keywords: PPARD, Peroxisome proliferator-activated receptor beta, Peroxisome proliferator-activated receptor delta, Nuclear hormone...
MW: 35.1 kD
From 281.00€ *
Review
GSK3787
GSK3787

Item number: TGM-T1941-100mg

Description: GSK3787 is a specific and irreversible PPARdelta inhibitor(pIC50= 6.6). Target: PPAR. Smiles: FC(F)(F)c1ccc(nc1)S(=O)(=O)CCNC(=O)c1ccc(Cl)cc1. References: Shearer BG, et al. J Med Chem, 2010, 53(4), 1857-1861.
Application: PPARbeta/delta antagonist
CAS 188591-46-0
MW: 392.78 D
From 49.00€ *
Review
GW 501516
GW 501516

Item number: TGM-T6151-10mg

Description: GW 501516 (Endurobol) is a effective and highly specifc PPARbeta/delta agonist (EC50: 1 nM), with 1000-fold selectivity over hPPARalpha/gamma. Target: Autophagy, PPAR. Smiles: C(SC1=CC(C)=C(OCC(O)=O)C=C1)C=2SC(=NC2C)C3=CC=C(C(F)(F)F)C=C3. References: Wei ZL, et al. A short and efficient synthesis of...
Keywords: Cardarine, GW501516, GW 1516, GSK-516, Endurobol
Application: PPARD agonist
CAS 317318-70-0
MW: 453.5 D
From 43.00€ *
Review
GW7647
GW7647

Item number: TGM-T15453-100mg

Description: GW7647 is a potent agonist of PPARalpha (EC50s: 6 nM, 1.1 µM, and 6.2 µM for human PPARalpha, PPARgamma, and PPARdelta, respectively). Target: PPAR. Smiles: CC(C)(Sc1ccc(CCN(CCCCC2CCCCC2)C(=O)NC2CCCCC2)cc1)C(O)=O. References: Luo M, et al. IL-1beta-Induced Downregulation of the Multifunctional PDZ...
Application: PPARalpha agonist
CAS 265129-71-3
MW: 502.75 D
From 45.00€ *
Review
MA-0204
MA-0204

Item number: TGM-T15945-100mg

Description: MA-0204 is a highly selective and orally available peroxisome proliferator-activated receptor delta (PPARdelta) modulator (EC50s: 0.4 nM, 7.9 nM and 10 nM for human, mouse and rat PPARdelta, respectively). It is a potential treatment for Duchene Muscular Dystrophy (DMD). Target: PPAR. Smiles:...
Application: PPARdelta agonist
CAS 2095128-17-7
MW: 476.49 D
From 88.00€ *
Review
GSK0660
GSK0660

Item number: TGM-T2674-100mg

Description: GSK0660 is an antagonist and inverse agonist of PPARbeta/delta. Target: PPAR. Smiles: S(NC1=C(OC)C=C(NC2=CC=CC=C2)C=C1)(=O)(=O)C3=C(C(OC)=O)SC=C3. References: Savage SR, et al. Mol Vis. 2015 May 20,21:568-76.
Application: PPARdelta antagonist
CAS 1014691-61-2
MW: 418.49 D
From 40.00€ *
Review
CAY10592
CAY10592

Item number: TGM-T35813-10mg

Description: Peroxisome proliferator-activated receptors (PPARs) alpha, delta, gamma are ligand-activated nuclear transcription factors involved in the regulation of energy homeostasis as well as insulin sensitivity and glucose metabolism. Pharmacologies of PPARdelta receptor agonists, though relatively obscure,...
Application: PPARdelta agonist
CAS 685139-10-0
MW: 568.71 D
From 88.00€ *
Review
1 from 7 pages