The following products have been found matching your search "K04467": 71

ACHP is an inhibitor of IkappaB kinase beta (IKKbeta) and IKKalpha (IC50s = 8.5 and 250 nM, respectively). It is selective for IKKbeta and IKKalpha over IKKgamma, Syk, and MKK4 (IC50s = >20 µM for all). It reduces the constitutive phosphorylation of IkappaBalpha and NF-kappaB p65 in U266 and NCU-MM-2 multiple...

White to light green solid. Soluble in DMSO, ethanol or dichloromethane. Insoluble in water. Anticancer and antiangiogenic compound. Induces apoptosis, cell cycle arrest and autophagy in various cancer cell lines, At low concentrations acts as antioxidant reducing oxidative stress generated through the TCR signaling...

Wedelolactone is a natural coumestan originally isolated from plants used in herbal therapies. It inhibits NF-kappaB signaling at the level of IKK action, resulting in suppression of NF-kappaB-mediated gene expression at concentrations of 1-100 µM. Wedelolactone can also inhibit hepatitis C virus NS5B RNA-dependent...

Protein function: Serine kinase that plays an essential role in the NF- kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of...

Protein function: Serine kinase that plays an essential role in the NF- kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of...

Protein function: Serine kinase that plays an essential role in the NF- kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of...

Anti-IKKalpha Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with IKK? from Human, Mouse and New World Monkey based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-IKK? from other sources has not been determined. Protein function:...

Anti-IKK alpha Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Antibody has no cross response to IKKb or IKKg. Protein function: Serine kinase that plays an essential role in the NF- kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory...

Anti-IKK alpha Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. This polyclonal antibody has no cross response to IKKb or IKKy. Protein function: Serine kinase that plays an essential role in the NF- kappa-B signaling pathway which is activated by multiple stimuli such as...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. IKBKA, also called CHUK, NFKBIKA, IKKA, IKK1, I-KAPPA-B, is a protein kinase that in humans is encoded by the CHUK gene. It is a member of the protein kinase superfamily. The protein contains a serine/threonine kinase domain. IKKa is expressed in a broad array...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Inhibitor of nuclear factor kappa-B kinase subunit alpha, also known as conserved helix-loop-helix ubiquitous kinase (CHUK) or IKBKA, is a protein kinase that in humans is encoded by the CHUK gene. It is mapped to 10q24.31. This gene encodes a member of the...

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Conserved helix-loop-helix ubiquitous kinase Protein function: Serine kinase that plays an essential role in the NF- kappa-B signaling pathway which is activated by multiple stimuli such as...