46 products were found matching "K04465"!

DIM-C-pPhCO2Me is a nerve growth factor IB (NR4A1) antagonist. It decreases expression of the mRNA encoding integrin beta1 (ITGB1) in MIA PaCa-2 and PANC-1 pancreatic and RKO and SW480 colon cancer cells when used at concentrations of 15 and 20 µM. DIM-C-pPhCO2Me (15 and 20 µM) decreases the migration and adhesion...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat NGFIB. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat NGFIB. Next,...

Cytosporone B is a naturally occurring agonist for the nuclear receptor Nur77 (IC50 = 0.278 nM). Activation of Nur77 with cytosporone B induces the expression of Nur77-dependent genes, including the gene for Nur77 itself. Signaling through Nur77 induces apoptosis in cancer cells and retards xenograft tumor growth....

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Nuclear receptor subfamily 4, group A, member 1, NR4A1 Protein function: Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during...

C-DIM5 is a para-phenyl-substituted diindolylmethane (C-DIM) and an agonist of the orphan receptor nuclear receptor-related protein 77 (Nur77). It selectively activates Nur77 over peroxisome proliferator receptor gamma (PPARgamma) in reporter assays when used at a concentration of 20 µM. C-DIM5 (10, 15, and 20 µM)...

C-DIM8 is a para-phenyl-substituted diindolylmethane (C-DIM) and an antagonist of the orphan receptor nuclear receptor-related protein 77 (Nur77). It inhibits reporter gene expression induced by the Nur77 agonist C-DIM5 (Cay-27980) in PANC-28 cells when used at a concentration of 20 µM. C-DIM8 (10, 15, and 20 µM)...

Protein function: Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'- AAAAGGTCA-3'. May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Nuclear receptor subfamily 4 group A member 1, also called NAK1, GFRP1, TR3, NUR77 or NGFIB, is a protein that in humans is encoded by the NR4A1 gene, and is a member of the Nur nuclear receptor family of intracellular transcription factors. NR4A1 is involved in...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Nuclear receptor subfamily 4, group A, member 1, also called NAK1, GFRP1, TR3, NUR77 or NGFIB, is a protein that in humans is encoded by the NR4A1 gene, and a member of the Nur nuclear receptor family of intracellular transcription factors. NR4A1 is involved in...

In 1X PBS, pH 7.4, with 0.09% sodium azide. NR4A1 is a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. This protein acts as a nuclear transcription factor. Translocation of the...

Protein function: Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'- AAAAGGTCA-3'. May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the...

Protein function: Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'- AAAAGGTCA-3'. May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the...