81 products were found matching "K04430"!

HRX215 is an inhibitor of MAP kinase kinase 4 (MKK4, IC50 = 0. µM). It is selective for MKK4 over JNK1, B-RAF, and MKK7 (IC50s = 7. 11. and 14. µM, respectively). HRX215 (10 mg/kg) decreases hepatocyte apoptosis in a mouse model of liver damage induced by carbon tetrachloride (CCl4). It increases survival and...

Protein function: Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Essential component of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. With MAP2K7/MKK7, is the one of the only known kinase to directly...

Protein function: Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Essential component of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. With MAP2K7/MKK7, is the one of the only known kinase to directly...

Protein function: Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Essential component of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. With MAP2K7/MKK7, is the one of the only known kinase to directly...

Protein function: Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Essential component of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. With MAP2K7/MKK7, is the one of the only known kinase to directly...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Dual specificity mitogen-activated protein kinase kinase 4 (MAP2K4), also called MEK4, SEK1, JNKK1 and MKK4, is an enzyme that in humans is encoded by the MAP2K4 gene. It is mapped to 17p12. This gene encodes a dual specificity protein kinase that belongs to the...

Vacquinols are a new class of quinine-derivatives that stimulate death in glioblastoma cells by massive macropinocytotic vacuolization, ATP depletion, and cytoplasmic membrane rupture. A key effector of vacquinols is MAPK kinase 4 (MKK4). Vacquinol-1 is an activator of MKK4-dependent macropinocytotic cell death in...

SEK1/MKK4 (Phospho-Thr261) Colorimetric Cell-Based ELISA Kit Protein function: Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Essential component of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. With...

SEK1/MKK4 (Phospho-Ser80) Colorimetric Cell-Based ELISA Kit Protein function: Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Essential component of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. With...

Map2k4 Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Mouse, Rat, Human and for use in ELISA, WB applications. Map2k4 Antibody is a high quality polyclonal antibody for research use only.. Protein function: Dual specificity protein kinase which acts as an essential component of the...

Protein function: Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Essential component of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. With MAP2K7/MKK7, is the one of the only known kinase to directly...

Recombinant human full-length MKK4 (dual-specificity mitogen-activated protein kinase kinase 4, also known as MAP2K4 or MAPKK4). This construct contains an N-terminal His-tag. The recombinant protein was affinity purified and is active.