33 products were found matching "K04415"!

1 from 3 pages
No results were found for the filter!
Tpl2 Kinase Inhibitor
Tpl2 Kinase Inhibitor

Item number: Cay19710-1

Tpl2 kinase inhibitor is an inhibitor of tumor progression locus 2 (Tpl2, IC50 = 0.05 µM). It is selective for Tpl2 over MEK, p38 MAPK, Src, MK2, and PKC (IC50s = >40, 180, >400, 110, and >400 µM, respectively). Tpl2 kinase inhibitor inhibits LPS-induced TNF-alpha production in isolated human monocytes and whole...
Keywords: c-Cot Kinase Inhibitor, MAP3K8 Kinase Inhibitor, Tumor Progression Locus 2 Kinase Inhibitor,...
Application: c-Cot (MAP3K8) inhibitor
CAS 871307-18-5
MW: 404.8 D
From 77.00€ *
Review
Tpl2 Kinase Inhibitor (hydrochloride)
Tpl2 Kinase Inhibitor (hydrochloride)

Item number: Cay34059-1

Tpl2 kinase inhibitor is an inhibitor of tumor progression locus 2 (Tpl2, IC50 = 0.05 µM). It is selective for Tpl2 over MEK, p38 MAPK, Src, MK2, and PKC (IC50s = >40, 180, >400, 110, and >400 µM, respectively). Tpl2 kinase inhibitor inhibits LPS-induced TNF-alpha production in isolated human monocytes and whole...
Keywords: c-Cot Kinase Inhibitor, MAP3K8 Kinase Inhibitor, Tumor Progression Locus 2 Kinase Inhibitor,...
Application: MAP3K8/COT/Tpl2 inhibitor
MW: 404.8 D
From 77.00€ *
Review
Cot (MAP3K8), GST-His-tags
Cot (MAP3K8), GST-His-tags

Item number: BPS-40050

Human Cot/Tpl2 (GenBank Accession No. NM_005204), (a.a. 30-397), with N-terminal GST-His-tag, MW= 72 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
Keywords: COT, TPL-2, MAP3K8, EC=2.7.11.25, Proto-oncogene c-Cot, Tumor progression locus 2, Cancer Osaka thyroid oncogene,...
Application: Enzyme kinetics, inhibitor screening, selectivity profiling
Expressed in: insect cells
Origin: human
MW: 72 kD
525.00€ *
Review
Cot/Tpl2, mouse recombinant protein
Cot/Tpl2, mouse recombinant protein

Item number: BPS-41050

Mouse, recombinant, N-terminal His-GST-tag Description: Mouse Cot kinase (MAP3K8) GenBank Accession No. NM_007746, a.a. 30-397, with N-terminal His-GST-tag, expressed in a Baculovirus infected Sf9 cell expression system. The theoretical MW is 70 kDa. Specific Activity: 8.5 pmole/min/mg
Keywords: Cot, TPL-2, Map3k8, EC=2.7.11.25, Proto-oncogene c-Cot, Tumor progression locus 2, Cancer Osaka thyroid oncogene,...
Application: Enzyme kinetics
Expressed in: Baculovirus
Origin: mouse
MW: 70 kD
525.00€ *
Review
Anti-MAP3K8
Anti-MAP3K8

Item number: ARG58418.100

Protein function: Required for lipopolysaccharide (LPS)-induced, TLR4- mediated activation of the MAPK/ERK pathway in macrophages, thus being critical for production of the proinflammatory cytokine TNF- alpha (TNF) during immune responses. Involved in the regulation of T-helper cell differentiation and IFNG...
Keywords: Anti-COT, Anti-TPL-2, Anti-MAP3K8, EC=2.7.11.25, Anti-Proto-oncogene c-Cot, Anti-Tumor progression locus 2, Anti-Cancer...
Application: WB
Host: Rabbit
Species reactivity: human, mouse
624.00€ *
Review
Anti-MAP3K8
Anti-MAP3K8

Item number: ARG58432.50

Protein function: Required for lipopolysaccharide (LPS)-induced, TLR4- mediated activation of the MAPK/ERK pathway in macrophages, thus being critical for production of the proinflammatory cytokine TNF- alpha (TNF) during immune responses. Involved in the regulation of T-helper cell differentiation and IFNG...
Keywords: Anti-COT, Anti-TPL-2, Anti-MAP3K8, EC=2.7.11.25, Anti-Proto-oncogene c-Cot, Anti-Tumor progression locus 2, Anti-Cancer...
Application: IHC (paraffin), WB
Host: Rabbit
Species reactivity: human, rat
520.00€ *
Review
MAP3K8 (Phospho-Thr290) Colorimetric Cell-Based ELISA Kit
MAP3K8 (Phospho-Thr290) Colorimetric Cell-Based ELISA Kit

Item number: G-CBCAB01238.96

MAP3K8 (Phospho-Thr290) Colorimetric Cell-Based ELISA Kit Protein function: Required for lipopolysaccharide (LPS)-induced, TLR4-mediated activation of the MAPK/ERK pathway in macrophages, thus being critical for production of the proinflammatory cytokine TNF-alpha (TNF) during immune responses. Involved in the...
Keywords: COT, TPL-2, MAP3K8, EC=2.7.11.25, Proto-oncogene c-Cot, Tumor progression locus 2, Cancer Osaka thyroid oncogene,...
Application: In-cell ELISA
641.00€ *
Review
Anti-MAP3K8
Anti-MAP3K8

Item number: G-CAB15623.100

WB 1:500 - 1:2000. Protein function: Required for lipopolysaccharide (LPS)-induced, TLR4- mediated activation of the MAPK/ERK pathway in macrophages, thus being critical for production of the proinflammatory cytokine TNF- alpha (TNF) during immune responses. Involved in the regulation of T-helper cell...
Keywords: Anti-COT, Anti-TPL-2, Anti-MAP3K8, EC=2.7.11.25, Anti-Proto-oncogene c-Cot, Anti-Tumor progression locus 2, Anti-Cancer...
Application: WB
Host: Rabbit
Species reactivity: human, mouse, rat
From 352.00€ *
Review
Anti-MAP3K8
Anti-MAP3K8

Item number: ATA-HPA017962.100

Protein function: Required for lipopolysaccharide (LPS)-induced, TLR4-mediated activation of the MAPK/ERK pathway in macrophages, thus being critical for production of the proinflammatory cytokine TNF-alpha (TNF) during immune responses. Involved in the regulation of T-helper cell differentiation and IFNG expression...
Keywords: Anti-COT, Anti-TPL-2, Anti-MAP3K8, EC=2.7.11.25, Anti-Proto-oncogene c-Cot, Anti-Tumor progression locus 2, Anti-Cancer...
Application: ICC, IHC, WB
Host: Rabbit
Species reactivity: human
From 300.00€ *
Review
Anti-MAP3K8
Anti-MAP3K8

Item number: E-AB-91223.120

This gene is an oncogene that encodes a member of the serine/threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This...
Keywords: COT, TPL-2, MAP3K8, EC=2.7.11.25, Proto-oncogene c-Cot, Tumor progression locus 2, Cancer Osaka thyroid oncogene,...
Application: WB
Host: Rabbit
Species reactivity: human, mouse, rat
From 198.00€ *
Review
-10 %
Discount Promotion
Anti-phospho-Cot (Thr290)
Anti-phospho-Cot (Thr290)

Item number: ELK-ES1516.100

This gene is an oncogene that encodes a member of the serine/threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This...
Keywords: Anti-phospho-COT, Anti-phospho-TPL-2, Anti-phospho-MAP3K8, EC=2.7.11.25, Anti-phospho-Proto-oncogene c-Cot,...
Application: WB, IHC, IF, ELISA
Host: Rabbit
Species reactivity: human, mouse, rat
169.00€ * From 152.10€ *
Review
-10 %
Discount Promotion
Anti-COT
Anti-COT

Item number: ELK-ES2031.100

This gene is an oncogene that encodes a member of the serine/threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This...
Keywords: Anti-COT, Anti-TPL-2, Anti-MAP3K8, EC=2.7.11.25, Anti-Proto-oncogene c-Cot, Anti-Tumor progression locus 2, Anti-Cancer...
Application: WB, IHC, IF, ELISA
Host: Rabbit
Species reactivity: human, mouse, rat
169.00€ * From 152.10€ *
Review
1 from 3 pages