47 products were found matching "K04411"!

STK3(serine/threonine kinase 3) Homo sapiens This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is...

Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. MST1 antibody detects Mammalian STE20-like protein kinase 1, a serine/threonine kinase that functions as a central regulator of apoptosis, stress signaling, and organ size control. The UniProt recommended name is Serine/threonine-protein...

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. Phospho-MST1/MST2 (Thr183/Thr180) antibody detects the phosphorylated forms of MST1 (Thr183) and MST2 (Thr180), two core kinases in the Hippo signaling pathway. MST1 and MST2 are serine/threonine...

IHMT-MST1-58 is an inhibitor of mammalian Ste20-like protein kinase 1 (MST1, IC50 = 23 nM). It is selective for MST1 over MST2 and NIMA-related kinase 3 (NEK3, IC50s = 652 and >10,000 nM, respectively). IHMT-MST1-58 (50 mg/kg per day) reduces fasting blood glucose levels in mice in models of type 1- or type 2...

Protein function: Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by...

Protein function: Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by...

XMU-MP-1 is an inhibitor of the pro-apoptotic, sterile 20-like kinases MST1 and 2 (IC50s = 71.1 and 38.1 nM, respectively). It is selective for MST1 and 2 over a panel of 468 kinases at a concentration of 1 µM. XMU-MP-1 inhibits phosphorylation of MOB1, LATS1 and 2, and YAP in HepG2 cells as well as MST1 and 2...

Description: XMU-MP-1 is an inhibitor of the pro-apoptotic, sterile 20-like kinases MST1 and 2. Target: Hippo pathway. Smiles: CN1c2ccsc2C(=O)N(C)c2cnc(Nc3ccc(cc3)S(N)(=O)=O)nc12. References: Fan F, et al. Pharmacological targeting of kinases MST1 and MST2 augments tissue repair and regeneration. Sci Transl Med....

Human STK4 (serine/threonine kinase 4), also known as MST-1 (Mammalian STE20-like protein kinase 1) or KRS2, GenBank Accession No. NM_006282, amino acids 2-488(end), with N-terminal GST-tag, MW=81.5 kDa, expressed in Sf9 insect cells via a baculovirus expression system.

Sterile-20 (Ste20) is a serine/threonine kinase in Saccharomyces cerevisiae that is involved in relaying signals from G protein-coupled receptors to cyto-solic MAP kinase cascades. Mammalian protein kinases that display sequence similarity to Ste20 are divided into two groups, the PAK subfamily and the GCK...

In 1X PBS, pH 7.4, with 0.09% sodium azide. MST1 is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A...

Sterile-20 (Ste20) is a serine/threonine kinase in Saccharomyces cerevisiae that is involved in relaying signals from G protein-coupled receptors to cyto-solic MAP kinase cascades. Mammalian protein kinases that display sequence similarity to Ste20 are divided into two groups, the PAK subfamily and the GCK...